LEADER 05349nam 2200673Ia 450 001 9911018976103321 005 20200520144314.0 010 $a9786610520442 010 $a9781280520440 010 $a1280520442 010 $a9783527605354 010 $a3527605355 010 $a9783527602605 010 $a3527602607 035 $a(CKB)1000000000019334 035 $a(EBL)481738 035 $a(OCoLC)85820421 035 $a(SSID)ssj0000195513 035 $a(PQKBManifestationID)11169273 035 $a(PQKBTitleCode)TC0000195513 035 $a(PQKBWorkID)10130115 035 $a(PQKB)11570404 035 $a(MiAaPQ)EBC481738 035 $a(Perlego)2770719 035 $a(EXLCZ)991000000000019334 100 $a20030307d2004 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMain group metals in organic synthesis /$fedited by Hisahi Yamamoto and Koichiro Oshima 210 $aWeinheim, Germany $cWiley-VCH$d2004 215 $a1 online resource (907 p.) 300 $aDescription based upon print version of record. 311 08$a9783527305087 311 08$a3527305084 320 $aIncludes bibliographical references and index. 327 $aMain Group Metals in Organic Synthesis; Contents; Preface; List of Contributors; Volume 1; 1 Lithium in Organic Synthesis; 1.1 Introduction; 1.2 Nature of Organolithium Compounds; 1.2.1 Overview; 1.2.2 Structural Features; 1.2.3 Configurational Stability; 1.2.4 Titration of Organolithium Compounds; 1.3 Methods for the Preparation of Organolithium Compounds; 1.3.1 Overview; 1.3.2 Reductive Lithiation using Lithium Metal; 1.3.3 Preparation of Organolithium Compounds from Another Organolithium Compounds; 1.3.3.1 Deprotonation; 1.3.3.2 Halogen-Lithium Exchange; 1.3.3.3 Transmetallation 327 $a1.3.3.4 Carbolithiation1.3.3.5 Miscellaneous; 1.4 Methods for Construction of Carbon Frameworks by Use of Organolithium Compounds; 1.4.1 Overview; 1.4.2 Stereospecificity; 1.4.3 Synthetic Application; 1.4.3.1 C-C Bond Formation: Conversion of C-Li to Halogen-Li; 1.4.3.2 C-C Bond Formation: Conversion of C-Li to O-Li; 1.4.3.3 C-C Bond Formation: Conversion of C-Li to N-Li; 1.5 References; 2 Rubidium and Cesium in Organic Synthesis; 2.1 Introduction; 2.2 Organo-, Silyl-, Germyl-, and Stannylmetal; 2.3 Fluoride Ion Source; 2.3.1 Nucleophilic Fluorination; 2.3.2 Desilylation Reactions 327 $a2.3.2.1 Carbanion Equivalent Formation2.3.2.2 Desilylation-Elimination; 2.4 Electrophilic Fluorination - Cesium Fluorosulfate; 2.5 Cesium Salts as Bases; 2.6 Cesium Enolate; 2.7 Catalytic Use; 2.8 Conclusion; 2.9 References; 3 Magnesium in Organic Synthesis; 3.1 Introduction; 3.2 Preparation of Organomagnesium Compounds; 3.2.1 Preparation from Alkyl Halides and Mg Metal; 3.2.2 Preparation with Rieke Magnesium; 3.2.3 Transmetalation; 3.2.4 Sulfoxide-Magnesium Exchange (Ligand Exchange Reaction of Sulfoxides with Grignard Reagent); 3.2.5 Hydromagnesation 327 $a3.2.6 Metalation (Deprotonation from Strong Carbon Acids)3.2.7 Other Preparative Methods; 3.3 Reaction of Organomagnesium Compounds; 3.3.1 Reaction with Organomagnesium Amides; 3.3.1.1 Preparation of Magnesium Monoamides and Bisamides; 3.3.1.2 Reaction with Organomagnesium Amide; 3.3.2 Cp(2)TiCl(2)- or Cp(2)ZrCl(2)-catalyzed Reaction with Grignard Reagents; 3.3.3 Substitution at Carbon by Organomagnesium Compounds; 3.3.4 Addition to Carbon-Carbon Multiple Bonds; 3.3.5 Addition of Organomagnesium Compounds to Carbonyl Groups; 3.4 Halogen-Magnesium Exchange Reactions 327 $a3.4.1 Practical Examples of Halogen-Magnesium Exchange Reactions3.4.1.1 Perfluoro Organomagnesium Reagents; 3.4.1.2 Polyhalogenated Arylmagnesium Reagents; 3.4.1.3 Exchange of Polyhalomethane Derivatives; 3.4.1.4 Preparation of Magnesiated Nitrogen-Heterocycles; 3.4.1.5 Formation of Enolates by Halogen-Magnesium Exchange; 3.4.1.6 Miscellaneous Reactions; 3.4.2 iPrMgBr-induced Halogen-Magnesium Exchange for the Preparation of Polyfunctional Organomagnesium Reagents; 3.4.2.1 Exchange Reaction of Aryl Halides; 3.4.2.2 Exchange Reaction of Heterocyclic Halides 327 $a3.4.2.3 Exchange Reaction of Alkenyl Halides 330 $aThis is the first handbook to cover in detail all aspects of this fascinating field of chemistry. In this handy two-volume set, readers will instantly find the information they need, clearly structured according to the individual metals in the main groups, hitherto only accessible after much time-consuming research. The result is in indispensable aid for everyday work in the lab.Alongside all the classical organic reactions, this book focuses on the modern variations as well as novel, current reactions in organic synthesis that are closely linked to main group elements - both stoechiometri 606 $aOrganometallic compounds$xSynthesis 606 $aOrganic compounds 615 0$aOrganometallic compounds$xSynthesis. 615 0$aOrganic compounds. 676 $a547.05 701 $aYamamoto$b Hisashi$066610 701 $aOshima$b Koichiro$f1947-$01838002 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911018976103321 996 $aMain group metals in organic synthesis$94416884 997 $aUNINA