LEADER 04907nam 2200709Ia 450 001 9911018924603321 005 20200520144314.0 010 $a9786612914171 010 $a9781444348293 010 $a1444348299 010 $a9781282914179 010 $a1282914170 010 $a9781444327335 010 $a144432733X 010 $a9781444327342 010 $a1444327348 035 $a(CKB)2670000000060751 035 $a(EBL)624715 035 $a(OCoLC)700701783 035 $a(MiAaPQ)EBC624715 035 $a(Perlego)1148944 035 $a(EXLCZ)992670000000060751 100 $a20100317d2011 uy 0 101 0 $aeng 135 $aur|n||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aGenetic and molecular aspects of sport performance /$fedited by Claude Bouchard and Eric P. Hoffman 210 $aChichester, West Sussex [England] ;$aHoboken, NJ $cWiley-Blackwell$d2011 215 $a1 online resource (420 p.) 225 1 $aEncyclopaedia of sports medicine ;$vv. 18 300 $a"An IOC Medical Commission publication." 311 08$a9781444334456 311 08$a144433445X 320 $aIncludes bibliographical references and index. 327 $aGenetic and Molecular Aspects of Sport Performance; Contents; List of Contributors; Foreword; Preface; Part 1 The Science of Genomics and Genetics; 1 The Human Genome and Epigenome; 2 Mitochondrial Medicine in Health and Disease: Interface Between Athletic Performance and Therapeutics; 3 Characterizing the Extent of Human Genetic Variation for Performance-Related Traits; 4 Current Proteome Profiling Methods; 5 Bioinformatics and Public Access Resources; 6 Search for Genes Influencing Complex Traits; Part 2 Evidence from Genetic Epidemiology Studies 327 $a7 Genetic Epidemiology, Physical Activity, and Inactivity8 Role of Genetics Factors in Sport Performance: Evidence from Family Studies; 9 Twin Studies in Sport Performance; 10 Twin and Family Studies of Training Responses; 11 Ethnic Differences in Sport Performance; 12 Selection Experiments in Rodents to Define the Complexity and Diversity of Endurance Capacity; Part 3 Contributions of Specific Genes and Markers; 13 Genes and Endurance Performance; 14 Genes and Strength and Power Phenotypes; 15 Genes and Response to Training 327 $a16 Genetic Determinants of Exercise Performance: Evidence from Transgenic and Null Mouse Models17 The ACE Gene and Performance; 18 The ACTN3 Gene and Human Performance; 19 Mitochondrial DNA Sequence Variation and Performance; 20 Genes, Exercise, and Lipid Metabolism; 21 Genes, Exercise, and Glucose and Insulin Metabolism; 22 Genes, Exercise, and Cardiovascular Phenotypes; 23 Genes, Exercise, and Protein Metabolism; 24 The Regulation of Physical Activity by Genetic Mechanisms: Is There a Drive to Be Active?; 25 Genes, Exercise, and Psychological Factors 327 $aPart 4 Systems Biology of Exercise and Training26 A Primer on Systems Biology, as Applied to Exercise Physiology and Metabolism; 27 Systems Biology Through Time Series Data-A Strength of Muscle Remodeling; 28 Proteomics in Exercise Training Research; 29 The Influence of Physical Exercise on Adult Stem Cells; Part 5 Ethical and Societal Implications; 30 Genetics and Ethics in Elite Sport; 31 Genes and Talent Selection; 32 Performance Enhancement by Gene Doping; 33 Bioethical Concerns in a Culture of Human Enhancement; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W 327 $aXY; Z 330 $aThis is the latest volume in the IOC Encyclopaedia of Sports Medicine series, summarizing the evidence from all relevant sources on the genetic and molecular basis of sports and other human physical performance. The initial chapters address the basic science of genomics and genetics and the regulation of gene expression. Additional chapters provide authoritative information on the genetics of complex performance phenotypes, the contributions of small animal research, family and twin studies, and ethnic comparisons. A final section addresses the issue of the contribution of specific 410 0$aEncyclopaedia of sports medicine ;$vv. 18. 606 $aSports$xPhysiological aspects 606 $aExercise$xPhysiological aspects 606 $aHuman genetics 606 $aAthletic ability 615 0$aSports$xPhysiological aspects. 615 0$aExercise$xPhysiological aspects. 615 0$aHuman genetics. 615 0$aAthletic ability. 676 $a612/.044 701 $aBouchard$b Claude$0939634 701 $aHoffman$b Eric P$092249 712 02$aIOC Medical Commission. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911018924603321 996 $aGenetic and molecular aspects of sport performance$94416592 997 $aUNINA