LEADER 01056nam--2200349---450- 001 990001750050203316 005 20050608085346.0 035 $a000175005 035 $aUSA01000175005 035 $a(ALEPH)000175005USA01 035 $a000175005 100 $a20040611d1971----km-y0itay0103----ba 101 0 $afre 102 $aFR 105 $a||||||||001yy 200 1 $aMersenne ou la naissance du mécanisme$fRobert Lenoble 210 $aParis$cVrin$d1971 215 $aLXIII; 633 p.$d24 cm 225 2 $a<>Histoire des Sciences textes et études$v3 410 0$12001$a<>Histoire des Sciences textes et études$v3 454 1$12001 461 1$1001-------$12001 700 1$aLENOBLE,$bRobert$0169133 801 0$aIT$bsalbc$gISBD 912 $a990001750050203316 951 $aII.1.D. 1439(IV C Coll. 35/3)$b79905 L.M.$cIV C 959 $aBK 969 $aUMA 979 $aSIAV2$b10$c20040611$lUSA01$h1725 979 $aCOPAT3$b90$c20050608$lUSA01$h0853 996 $aMersenne ou La naissance du mécanisme$9780603 997 $aUNISA LEADER 05840nam 2200781Ia 450 001 9911018920503321 005 20250604201344.0 010 $a9786610935109 010 $a9781280935107 010 $a1280935103 010 $a9780470114209 010 $a0470114207 010 $a9780470114193 010 $a0470114193 035 $a(CKB)1000000000355502 035 $a(EBL)312187 035 $a(OCoLC)173621245 035 $a(SSID)ssj0000146714 035 $a(PQKBManifestationID)11137545 035 $a(PQKBTitleCode)TC0000146714 035 $a(PQKBWorkID)10186608 035 $a(PQKB)10456289 035 $a(MiAaPQ)EBC312187 035 $a(Perlego)2758917 035 $a(EXLCZ)991000000000355502 100 $a20060815d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aEncyclopedia of infectious diseases $emodern methodologies /$fedited by Michel Tibayrenc 210 $aHoboken, N.J. $cWiley-Liss$dc2007 215 $a1 online resource (807 p.) 300 $aDescription based upon print version of record. 311 08$aPrint version: Encyclopedia of infectious diseases. Hoboken, N.J. : Wiley-Liss, ©2007 0471657328 9780471657323 (DLC) 2006026966 (OCoLC)71044505 311 08$a9780471657323 311 08$a0471657328 320 $aIncludes bibliographical references and index. 327 $aENCYCLOPEDIA OF INFECTIOUS DISEASES; Contents; Contributors; Biographical; Introduction: Infectious Diseases, the Major Challenge of Twenty-First Century Medicine; 1. Pulmonary Tuberculosis and Mycobacterium Tuberculosis: Modern Molecular Epidemiology and Perspectives; 1.1. Introduction; 1.2. General Points on Mycobacterium Tuberculosis (MTB) and Pulmonary Tuberculosis (PTB); 1.2.1. Classification and Cellular Characteristics; 1.2.2. Transmission and Multiplication of MTB; 1.2.3. Clinical and Subclinical TB; 1.2.4. Diagnosis of MTB Species; 1.2.5. Treatment, Drug Resistance, and Control 327 $a1.3. Genetics of MTB, Molecular Tools, and Population Structure1.3.1. Genome and Genetic Diversity of MTB; 1.3.2. Genetic Tools for Molecular Epidemiology; 1.3.3. How Should the Most Appropriate Molecular Marker be Chosen?; 1.3.4. Population Structure of MTB and Epidemiological Consequences; 1.4. Use of Molecular Epidemiology for Understanding Tuberculosis Transmission and Pathogenesis; 1.4.1. MTB Families and Worldwide Distribution; 1.4.2. MTB in Developing Versus Developed Countries; 1.4.3. Clinical and Epidemiological Relevance of Molecular Epidemiology at the Local Level 327 $a1.4.4. Use of Genotyping to Study the Impact of HIV/AIDS and Drug Resistance on Pathogenesis and Transmission1.5. Urgent Needs for TB Control, Limitations, and New Issues for Molecular Epidemiology; 1.5.1. Urgent Needs for TB Control and Molecular Epidemiology; 1.5.2. Limitations of Modern Molecular Tools; 1.5.3. Promising New Technologies; 1.6. Conclusion and Perspectives; Acknowledgments; Abbreviations; Glossary; References; 2. Diseases that Threaten Livestock; 2.1. Introduction; 2.2. Animal Diseases Under Control; 2.2.1. General Considerations; 2.2.2 Description of the Diseases 327 $a2.3. Diseases that Are an Economic Burden and Hamper International Trade in Animals and Animal Products2.3.1. General Considerations; 2.3.2. Description of the Diseases; 2.4. Animal Diseases that may Threaten Human Health; 2.4.1. Description of the Diseases; 2.5. Surveillance and Control of Transmissible Animal Diseases: Progress Expected from Modern Technologies; 2.6. Conclusion; References; 3. HIV/AIDS Infection in the World with a Special Focus on Africa; 3.1. Introduction; 3.2. Current State of the Epidemic; 3.2.1. Prevalences and Incidences in the World; 3.2.2. Mode of Transmission 327 $a3.2.3. Impact of HIV Infection on Other Endemic Diseases3.2.4. Demographic, Social, and Economic Consequences; 3.3. Molecular Epidemiology; 3.3.1. Classification of HIV; 3.3.2. Distribution of HIV-1 in Africa; 3.3.3. Implications of Recombination; 3.4. Implication of HIV Variability on Pathogenesis, Treatment, Diagnosis, and Vaccine Development in Africa; 3.4.1. Impact of HIV Variability on Diagnosis; 3.4.2. Impact of HIV Variability and Antiretroviral Therapy; 3.4.3. Impact of HIV Variability on Transmissibility and Pathogenesis; 3.4.4. Impact of HIV Variability on Vaccine Development 327 $a3.5. Access to Treatment 330 $aDiscover how the application of novel multidisciplinary, integrative approaches and technologies are dramatically changing our understanding of the pathogenesis of infectious diseases and their treatments. Each article presents the state of the science, with a strong emphasis on new and emerging medical applications. The Encyclopedia of Infectious Diseases is organized into five parts. The first part examines current threats such as AIDS, malaria, SARS, and influenza. The second part addresses the evolution of pathogens and the relationship between human genetic diversity and the spre 606 $aCommunicable diseases$vEncyclopedias 606 $aCommunicable diseases$xResearch$vEncyclopedias 606 $aResearch 606 $aCommunicable Diseases$3(DNLM)D003141 606 $aResearch$3(DNLM)D012106 608 $aEncyclopedia. 615 0$aCommunicable diseases 615 0$aCommunicable diseases$xResearch 615 0$aResearch. 615 2$aCommunicable Diseases. 615 2$aResearch. 676 $a362.196/9003 676 $a362.1969003 676 $a616.903 701 $aTibayrenc$b Michel$0889901 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911018920503321 996 $aEncyclopedia of infectious diseases$94416576 997 $aUNINA