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100   $a20031126d2004      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aCancer and inflammation $e[Symposium on Cancer and Inflammation, held at the Novartis Foundation, London, 12-14 November 2002 /$feditors, Derek J. Chadwick (organizer) and Jamie A. Goode]
210   $aChichester, U.K. ;$aHoboken, N.J. $cJohn Wiley & Sons$d2004
215   $a1 online resource (292 p.)
225 1 $aNovartis Foundation symposium ;$v256
300   $aDescription based upon print version of record.
311 08$a9780470855102 
311 08$a047085510X 
320   $aIncludes bibliographical references and index.
327   $aCANCER AND INFLAMMATION; Contents; Participants; Chair's introduction; Inflammation and cancer: an epidemiological perspective; Discussion; Chemokine-based pathogenetic mechanisms in cancer; Discussion; General discussion I; Anti-TNFa therapy of rheumatoid arthritis: what can we learn about chronic disease?; Discussion; How do chemokine/chemokine receptor activations affect tumorigenesis?; Discussion; Proinflammatory cytokines, immune response and tumour progression; Discussion; General discussion II; Lymphangiogenesis and tumour metastasis; Discussion
327   $aInfiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytesDiscussion; The influence of CD25(+) cells on the generation of immunity to tumour cell-lines in mice; Discussion; Macrophages: modulators of breast cancer progression; Discussion; Chemokines: angiogenesis and metastases in lung cancer; Discussion; Macrophage infiltration and angiogenesis in human malignancy; Discussion; The role of inflammation in tumour growth and tumour suppression; Discussion; Cyclooxygenase 2: from inflammation to carcinogenesis
327   $aDiscussionThe inflammatory cytokine network of epithelial cancer: therapeutic implications; Discussion; In vivo manipulation of DC migration and activation to elicit anti-tumour immunity; Discussion; Final general discussion; Concluding remarks; Index of contributors; Subject index
330   $aChronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and wound healing. The cells involved in inflammation are detected in a range of common cancers, together with the inflammatory cytokines and members of the chemokine ligand/receptor systems.Neutralization or deletion of the gene for some inflammatory cytokines confers resistance to tumour induction and experimental metastasis. Over-expression of such cytokines in tumour cells may enhance malignant potential. Certain chemokines are likely to subv
410  0$aNovartis Foundation symposium ;$v256.
606   $aCancer$xImmunological aspects$vCongresses
606   $aInflammation$vCongresses
615  0$aCancer$xImmunological aspects
615  0$aInflammation
676   $a616.99/4079
701   $aChadwick$b Derek$091632
701   $aGoode$b Jamie$0283336
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9911018917003321
996   $aCancer and inflammation$94417438
997   $aUNINA