LEADER 02691nam 2200709 a 450 001 9911018907403321 005 20200520144314.0 010 $a9786612784453 010 $a9783527642113 010 $a3527642110 010 $a9781282784451 010 $a1282784455 010 $a9783527630110 010 $a3527630112 010 $a9783527630127 010 $a3527630120 035 $a(CKB)2560000000011809 035 $a(EBL)540114 035 $a(OCoLC)642662062 035 $a(SSID)ssj0000413847 035 $a(PQKBManifestationID)11313091 035 $a(PQKBTitleCode)TC0000413847 035 $a(PQKBWorkID)10385247 035 $a(PQKB)11080743 035 $a(MiAaPQ)EBC540114 035 $a(MiAaPQ)EBC4042293 035 $a(Au-PeEL)EBL4042293 035 $a(CaPaEBR)ebr11114927 035 $a(CaONFJC)MIL278445 035 $a(OCoLC)958543997 035 $a(PPN)198080980 035 $a(Perlego)1012532 035 $a(EXLCZ)992560000000011809 100 $a20100629d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 04$aThe chemical biology of DNA damage /$fedited by Nicholas E. Geacintov and Suse Broyde 205 $a1st ed. 210 $aWeinheim [Germany] $cWiley$d2010 215 $a1 online resource (473 p.) 300 $aDescription based upon print version of record. 311 08$a9783527322954 311 08$a3527322957 320 $aIncludes bibliographical references and index. 327 $apt. 1. Chemistry and biology of DNA lesions -- pt. 2 New frontiers and challenges : understanding structure-function relationships and biological activity. 330 $aBringing the power of biochemical analysis to toxicology, this modern reference explains genotoxicity at the molecular level, showing the links between a DNA lesion and the resulting cellular or organismic response. Clearly divided into two main sections, Part 1 focuses on selected examples of important DNA lesions and their biological impact, while the second part covers current advances in assessing and predicting the genotoxic effects of chemicals, taking into account the biological responses mediated by the DNA repair, replication and transcription machineries.A ready reference for bio 606 $aDNA damage 615 0$aDNA damage. 676 $a572.8 676 $a572.86 22 701 $aGeacintov$b Nicholas E$01837468 701 $aBroyde$b Suse$01837469 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911018907403321 996 $aThe chemical biology of DNA damage$94416208 997 $aUNINA