LEADER 05699nam 2200745 a 450 001 9911018841003321 005 20200520144314.0 010 $a9786611032333 010 $a9781281032331 010 $a1281032336 010 $a9780470090244 010 $a0470090243 010 $a9780470090237 010 $a0470090235 035 $a(CKB)1000000000377484 035 $a(EBL)316224 035 $a(SSID)ssj0000234814 035 $a(PQKBManifestationID)11208130 035 $a(PQKBTitleCode)TC0000234814 035 $a(PQKBWorkID)10243127 035 $a(PQKB)11273833 035 $a(MiAaPQ)EBC316224 035 $a(OCoLC)181349678 035 $a(Perlego)2767436 035 $a(EXLCZ)991000000000377484 100 $a20070316d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aRegio- and stereo-controlled oxidations and reductions /$fedited by Stanley M. Roberts, John Whittall 210 $aChichester, England ;$aHoboken, NJ $cJohn Wiley$dc2007 215 $a1 online resource (336 p.) 225 1 $aCatalysts for fine chemical synthesis ;$vv. 5 300 $aDescription based upon print version of record. 311 08$a9780470090220 311 08$a0470090227 320 $aIncludes bibliographical references and index. 327 $aCatalysts for Fine Chemical Synthesis; Contents; Series Preface.; Preface to Volume 5; Abbreviations; 1 Industrial Catalysts for Regio- or Stereo-Selective Oxidations and Reductions A Review of Key Technologies and Targets; 1.1 Introduction; 1.2 Reduction of Carbon-Carbon Double Bonds; 1.2.1 Privileged structures: a-amino acids and itaconic acids; 1.2.2 b-Amino acids; 1.2.3 a-Alkyl substituted acids; 1.2.4 a-Alkoxy substituted acids; 1.2.5 Unsaturated nitriles; 1.2.6 Alkenes and allyl alcohols; 1.2.7 a,b-Unsaturated aldehyde reduction.; 1.3 Ketone and Imine Reduction 327 $a1.3.1 Catalytic hydrogenation of ketones and imines1.3.2 Asymmetric transfer hydrogenation (ATH) catalysts; 1.3.3 Modified borane reagents; 1.3.4 Biocatalysts (alcohol dehydrogenases and ketoreductases); 1.4 Oxidation; 1.4.1 Sharpless chiral epoxidation of allyl alcohols; 1.4.2 Dioxirane catalyzed epoxidation; 1.4.3 Amines and iminium salts; 1.4.4 Phase transfer catalysts; 1.4.5 The Julia ?-Colonna method (polyleucine oxidation); 1.4.6 Organocatalytic alfa-hydroxylation of ketones; 1.4.7 Baeyer-Villiger oxidation.; 1.4.8 Chiral sulfoxides.; References 327 $a2 Asymmetric Hydrogenation of Alkenes, Enones, Ene-Esters and Ene-Acids2.1 (S)-2,20-Bis{[di(4-methoxyphenyl)phosphinyl]oxy}-5,50,6,60,7,70,8,80-octahydro-1,10-binaphthyl as a ligand for rhodium-catalyzed asymmetric hydrogenation; 2.1.1 Synthesis of (S)-5,50,6,60,7,70,8,80-Octahydro-1,10-bi-2-naphthol; 2.1.2 Synthesis of (S)-2,20-Bis{[di(4-methoxyphenyl)phosphinyl]oxy}-5,50,6,60,7,70,8,80-octahydro-1,10-binaphthyl.; 2.1.3 Asymmetric hydrogenation of Dimethyl itaconate; Conclusion; References 327 $a2.2 Synthesis and application of phosphinite oxazoline iridium complexes for the asymmetric hydrogenation of alkenes2.2.1 Synthesis of (4S,5S)-2-(5-Methyl-2-phenyl-4,5-dihydro-oxazol-4-yl)-1,3-diphenyl-propan-2-ol; 2.2.2 Synthesis of (4S,5S)-O-[1-Benzyl-1-(5-methyl-2-phenyl-4,5-dihydro-oxazol-4-yl)-2-phenyl-ethyl]-diphenylphosphinite; 2.2.3 Synthesis of (4S,5S)-[(Z4-1,5-Cyclooctadiene)-{2-(2-phenyl-5-methyl-4,5-dihydro-oxazol-4-yl)-1,3-diphenyl-2-diphenylphosphinite-propane}iridium(I)]-tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; 2.2.4 Asymmetric hydrogenation of trans-a-Methylstilbene 327 $aConclusion.References; 2.3 Synthesis and application of heterocyclic phosphine oxazoline (HetPHOX) iridium complexes for the asymmetric hydrogenation of alkenes; 2.3.3 Synthesis of (4S)-[(Z4-1,5-Cyclooctadiene)-{4-tert-butyl-2-(3-diphenylphosphino-thiophene-2-yl)-4,5-dihydrooxazole}iridium(I)]-tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; 2.3.4 Asymmetric hydrogenation of trans-a-Methylstilbene; Conclusion; 2.3.1 Synthesis of (4S)-tert-Butyl-2-(thiophene-2-yl)-4,5-dihydrooxazole; 2.3.2 Synthesis of (4S)-tert-Butyl-2-(3-diphenylphosphinothiophene-2-yl)-4,5-dihydrooxazole; References 327 $a2.4 (R)-2,20,6,60-Tetramethoxy-bis[di(3,5-dimethylphenyl)phosphino]-3,30-bipyridine [(R)-Xyl-P-Phos] as a ligand for rhodiumcatalyzed asymmetric hydrogenation of a-dehydroamino acids. 330 $aVolume 5 in the Catalysts for Fine Chemical Synthesis series describes new procedures for the regio- and stereo-controlled transformations of compounds involving oxidation or reduction reactions. It describes a wide range of catalysts, including organometallic systems, biocatalysts and biomimetics. This volume also includes descriptions of a variety of conversions, including: Baeyer-Villiger oxidations; Epoxidation reactions; Hydroxylation reactions; Oxidation of alcohols to aldehydes, ketones and carboxylic acids; Reduction of ketones; and Reduction of alkenes including a, ß-unsaturate 410 0$aCatalysts for fine chemical synthesis ;$vv. 5. 606 $aOxidation 606 $aReduction (Chemistry) 606 $aOrganic compounds$xSynthesis 606 $aCatalysts 615 0$aOxidation. 615 0$aReduction (Chemistry) 615 0$aOrganic compounds$xSynthesis. 615 0$aCatalysts. 676 $a547/.23 701 $aRoberts$b Stanley M$0754844 701 $aWhittall$b John$01626846 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911018841003321 996 $aRegio- and stereo-controlled oxidations and reductions$94422070 997 $aUNINA