LEADER 01369aam 2200385I 450 001 9910710559903321 005 20160606093148.0 024 8 $aGOVPUB-C13-8271a68db7836d1a3085d0ad1fd515d9 035 $a(CKB)5470000002477697 035 $a(OCoLC)951215304 035 $a(EXLCZ)995470000002477697 100 $a20160606d1985 ua 0 101 0 $aeng 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aResponse behavior of hot-wires and films to flows of different gases /$fWilliam M. Pitts; Bernard J. McCaffrey 210 1$aGaithersburg, MD :$cU.S. Dept. of Commerce, National Institute of Standards and Technology,$d1985. 215 $a1 online resource 225 1 $aNBSIR ;$v85-3203 300 $a1985. 300 $aContributed record: Metadata reviewed, not verified. Some fields updated by batch processes. 300 $aTitle from PDF title page. 320 $aIncludes bibliographical references. 700 $aPitts$b William M$01391461 701 $aMcCaffrey$b Bernard J$01391462 701 $aPitts$b William M$01391461 712 02$aUnited States.$bNational Bureau of Standards. 801 0$bNBS 801 1$bNBS 801 2$bGPO 906 $aBOOK 912 $a9910710559903321 996 $aResponse behavior of hot-wires and films to flows of different gases$93445261 997 $aUNINA LEADER 04196nam 22006495 450 001 9911010533703321 005 20250612130258.0 010 $a981-9668-31-X 024 7 $a10.1007/978-981-96-6831-1 035 $a(MiAaPQ)EBC32153440 035 $a(Au-PeEL)EBL32153440 035 $a(CKB)39256378400041 035 $a(DE-He213)978-981-96-6831-1 035 $a(OCoLC)1523369944 035 $a(EXLCZ)9939256378400041 100 $a20250612d2025 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aDeciphering The Role of Succinate Dehydrogenase in Drug Discovery $eSDH in Drug Discovery /$fedited by Vaishali Manikrao Patil, Dileep Kumar, Satya P. Gupta 205 $a1st ed. 2025. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2025. 215 $a1 online resource (439 pages) 311 08$a981-9668-30-1 327 $aChapter 1. Succinate Dehydrogenase: Structure, Function and Significance -- Chapter 2. The Function of Succinate Dehydrogenase in Maintaining Normal Health -- Chapter 3. Role of Succinate Dehydrogenase in Cellular Respiration -- Chapter 4. Succinate Dehydrogenase: An Important Target in Drug Discovery for Tropical and Neglected Diseases -- Chapter 5. Succinate Dehydrogenase in Mitochondrial Disorders -- Chapter 6. Role of SDH in Cardiovascular Disorders -- Chapter 7. Implication of Succinate Dehydrogenase in Cancer -- Chapter 8. SDH and its Impact on Neurodegenerative Diseases: Autophagy in Neuroinflammation Perspective -- Chapter 9. Neurodegenerative Diseases and Succinate Dehydrogenase: A Therapeutics Avenue for Treatment -- Chapter 10. Fungicidal SDH Inhibitors in Agriculture: Regulation and Future Perspectives -- Chapter 11. Metabolic Disorders and Succinate Dehydrogenase. 330 $aThe book explores various aspects of Succinate Dehydrogenase (SDH) (an enzyme crucial for cellular respiration and energy production) from its assembly and regulation mechanisms to its deficiency and its implications in related disorders. It also encompasses the impact of SDH in obstructive pulmonary disorders, discussing its potential contributions and implications. It explores the design and development of SDH inhibitors as potent agent against fungal infections. It further examines the relationship between SDH mutations and cancer development, linking genetic alterations to tumorigenesis. The book focuses on therapeutic strategies and highlights the role of SDH in managing gastrointestinal tumors, neurodegenerative disorders, and aging-related diseases. It navigates through the challenges and prospects of utilizing SDH as a target for therapeutic interventions. The book also dives into the diagnostic aspects of SDH defects, elucidating their implications and potential diagnosticinvestigations. It serves as a comprehensive guide to unravel SDH's functions, dysfunctions, and therapeutic potentials. By amalgamating diverse areas such as enzymology, genetics, pharmacology, and disease management, this book emerges as an invaluable resource for researchers, clinicians, and students alike. 606 $aPharmacovigilance 606 $aDrug delivery systems 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aPharmacology 606 $aDrug Safety and Pharmacovigilance 606 $aDrug Delivery 606 $aBiomedical Research 606 $aPharmacology 615 0$aPharmacovigilance. 615 0$aDrug delivery systems. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aPharmacology. 615 14$aDrug Safety and Pharmacovigilance. 615 24$aDrug Delivery. 615 24$aBiomedical Research. 615 24$aPharmacology. 676 $a353.998 700 $aPatil$b Vaishali Manikrao$01828543 701 $aKumar$b Dileep$01426826 701 $aGupta$b Satya P$0944589 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911010533703321 996 $aDeciphering the Role of Succinate Dehydrogenase in Drug Discovery$94397460 997 $aUNINA