LEADER 03793nam 22006135 450 001 9911010529503321 005 20250612130300.0 010 $a3-031-87919-8 024 7 $a10.1007/978-3-031-87919-7 035 $a(MiAaPQ)EBC32153425 035 $a(Au-PeEL)EBL32153425 035 $a(CKB)39256374100041 035 $a(DE-He213)978-3-031-87919-7 035 $a(OCoLC)1523375684 035 $a(EXLCZ)9939256374100041 100 $a20250612d2025 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPhysiology and Pathophysiology of Oligodendroglia /$fedited by Chenju Yi, Arthur Butt, Alexei Verkhratsky, Jianqin Niu 205 $a1st ed. 2025. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2025. 215 $a1 online resource (676 pages) 225 1 $aAdvances in Neurobiology,$x2190-5223 ;$v43 311 08$a3-031-87918-X 327 $aPreface -- Chapter 1: Oligodendroglial lineage, myelin and white matter: defining the connectome of the human brain -- Part I: Physiology of oligodendroglia -- Chapter 2: Evolution of myelin and oligodendroglia -- Chapter 3: Development of oligodendroglia and myelin -- Chapter 4: Seeing is believing: insights into myelination and remyelination in zebrafish -- Chapter 5: Morphology of oligodendroglial cells and myelin -- Chapter 6: Physiology of oligodendroglial cells -- Chapter 7: Biochemistry and structure of myelin -- Chapter 8: Plasticity of myelination -- Part II: Pathophysiology of oligodendroglia -- Chapter 9: Demyelination and remyelination: General principles -- Chapter 10: Leukomalacia -- Chapter 11: White matter injury in the brain and spinal cord -- Chapter 12: Multiple sclerosis -- Chapter 13: Ageing and neurodegeneration of oligodendroglia -- Chapter 14: Protein pathologies in oligodendroglia in neurodegenerative diseases -- Chapter 15: Mental disorders -- Chapter 16: Neuromyelitis Optica -- Epilogue. 330 $aThis single volume provides a comprehensive description of oligodendroglia, the neural cells responsible for myelination of axons throughout the central nervous system. Myelinated axons create the white matter (connectome) of the human brain and spinal cord, which connect and synchronize hundreds of billions of neurons, thus defining the information processing function of the central nervous system. Oligodendrocytes and myelination play an essential role in regulating every bodily function and behavior. Damage to white matter, myelin, and oligodendrocytes results in severe diseases of the CNS. Pathology and Pathophysiology of Oligodendroglia, presented by the major authorities in the field, is the very first reference to combine, under a single cover, a full and detailed description of the physiology and pathophysiology of oligodendroglia, with a particular emphasis on neurodegenerative diseases. 410 0$aAdvances in Neurobiology,$x2190-5223 ;$v43 606 $aNeurophysiology 606 $aNeurons 606 $aNeurosciences 606 $aCellular Neuroscience 606 $aNeuroscience 606 $aNeurophysiology 615 0$aNeurophysiology. 615 0$aNeurons. 615 0$aNeurosciences. 615 14$aCellular Neuroscience. 615 24$aNeuroscience. 615 24$aNeurophysiology. 676 $a612.81046 700 $aYi$b Chenju$01828715 701 $aButt$b Arthur$01344575 701 $aVerkhratskii?$b A. N$g(Aleksei? Nestorovich)$0917755 701 $aNiu$b Jianqin$01828716 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911010529503321 996 $aPhysiology and Pathophysiology of Oligodendroglia$94397630 997 $aUNINA