LEADER 05939nam 22007215 450 001 9911007484303321 005 20250603132136.0 010 $a3-031-93848-8 024 7 $a10.1007/978-3-031-93848-1 035 $a(CKB)39160872400041 035 $a(MiAaPQ)EBC32145079 035 $a(Au-PeEL)EBL32145079 035 $a(DE-He213)978-3-031-93848-1 035 $a(OCoLC)1524421040 035 $a(EXLCZ)9939160872400041 100 $a20250603d2025 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aUniversal Access in Human-Computer Interaction $e19th International Conference, UAHCI 2025, Held as Part of the 27th HCI International Conference, HCII 2025, Gothenburg, Sweden, June 22?27, 2025, Proceedings, Part I /$fedited by Margherita Antona, Constantine Stephanidis 205 $a1st ed. 2025. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2025. 215 $a1 online resource (540 pages) 225 1 $aLecture Notes in Computer Science,$x1611-3349 ;$v15780 311 08$a3-031-93847-X 327 $aUniversal Access Theory and Practice Interacting Physically with USB Cables: Are Type-C Connectors more Usable than Type-A? -- Insights into the Practical Implementation of Participation in Work in Sheltered Workshops in Germany: Potentials and Obstacles to Transitions to the General Labour Market -- Enhancing Universal Access to QoL Assessments: Integrating WHODAS 2.0 and Chatbots -- Personas of Autistic Office Workers: A Foundation for Developing Effective Assistive Technologies -- Integrating Automated Perforator Analysis for Breast Reconstruction in Medical Imaging Workflow -- The Universal Design of ICT Maturity Model (UDMM) -- Evaluating Conformance of Video Safety Tools for Photosensitive Epilepsy -- Evaluating Cognitive Accessibility: Tools and Guidelines for Web Design -- Web Accessibility for the Elderly -- Exploring Stakeholder Perspectives on Measuring the Impact and Costs of Universal Design of Workplace ICT and the Consequences of Neglecting It -- Exploring the Technical and Cognitive Accessibility of Cookie Consent Banners for People with Varying Abilities -- Bridging Communication Gaps: Conceptual Enhancements for Video Conferencing with Autistic Users -- Multimodality and UI Adaptation A Proposal for an Adaptive Compiler Architecture and Design for Precision and Scale Aware Compilation Using Data-oriented Design -- Application of Multimodal Information Fusion in Intelligent Pedometers for Visually Impaired Children -- A Method for Selecting Characters by Moving Your Feet Back and Forth -- ?Which Login Method Should I Choose?? A Comparison of User-selectable Two-Factor Authentication Technologies -- Evaluation of Open-Source Upper Limb Prostheses Models for 3D Printing: Grasping Performance using Silicone Fingertips Covers -- Beyond Touchscreens: Dynamic and Multimodal Interaction Needs -- Universal Access and AI Artificial Intelligence and Assistive Technologies: A Systematic Review of Educational Applications for Disabilities -- Enhancing Communication for Individuals with Complex Communication Needs (CCN) through AI and Visual Scene Display Technology -- Clinical Annotation and Medical Image Anonymization for AI Model Training in Lung Cancer Detection -- Integration of Data Fusion and Deep Neural Networks for in-Vehicle Symbiotic HMI Design -- Automated Task Extraction from Emails: Aiding Autistic Individuals in the Workplace -- Design and Evaluation of LLM-Based Conversational Virtual Characters to Assist Adults with ADHD -- Exploring the Inclusive Potential of AI Chatbots: Engagement and Barriers in Foreign Language Training -- Modular Dynamic Neural Network with Swin Transformer and AutoML. 330 $aThis 2-volume set LNCS 15780-15781 constitutes the refereed proceedings of the 19th International Conference on Universal Access in Human-Computer Interaction, UAHCI 2025, held as part of the 27th International Conference, HCI International 2025, in Gothemburg, Sweden during June 22nd to 27th, 2025. The total of 1430 papers and 355 posters included in the HCII 2025 proceedings was carefully reviewed and selected from 7972 submissions. The two volumes cover topics as follows: Universal Access Theory and Practice Multimodality and UI Adaptation Universal Access and AI Inclusive Virtual and Augmented Reality Inclusive Learning and Playing. 410 0$aLecture Notes in Computer Science,$x1611-3349 ;$v15780 606 $aUser interfaces (Computer systems) 606 $aHuman-computer interaction 606 $aComputer engineering 606 $aComputer networks 606 $aImage processing$xDigital techniques 606 $aComputer vision 606 $aArtificial intelligence 606 $aUser Interfaces and Human Computer Interaction 606 $aComputer Engineering and Networks 606 $aComputer Imaging, Vision, Pattern Recognition and Graphics 606 $aArtificial Intelligence 615 0$aUser interfaces (Computer systems) 615 0$aHuman-computer interaction. 615 0$aComputer engineering. 615 0$aComputer networks. 615 0$aImage processing$xDigital techniques. 615 0$aComputer vision. 615 0$aArtificial intelligence. 615 14$aUser Interfaces and Human Computer Interaction. 615 24$aComputer Engineering and Networks. 615 24$aComputer Imaging, Vision, Pattern Recognition and Graphics. 615 24$aArtificial Intelligence. 676 $a005.437 676 $a004.019 700 $aAntona$b Margherita$01372616 701 $aStephanidis$b Constantine$0851700 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911007484303321 996 $aUniversal Access in Human-Computer Interaction$93403615 997 $aUNINA LEADER 05435nam 2201393z- 450 001 9910585940503321 005 20220812 035 $a(CKB)5600000000483077 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/91184 035 $a(oapen)doab91184 035 $a(oapen)91184 035 $a(EXLCZ)995600000000483077 100 $a20202208d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFrom a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (234 p.) 311 08$a3-0365-4753-3 311 08$a3-0365-4754-1 330 $aThis book collects contributions published in the Special Issue "From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential" and dealing with successful stories of drug improvement or design using classic protocols, quantum mechanical mechanistic investigation, or hybrid approaches such as QM/MM or QM/ML (machine learning). In the last two decades, computer-aided modeling has strongly supported scientists' intuition to design functional molecules. High-throughput screening protocols, mainly based on classical mechanics' atomistic potentials, are largely employed in biology and medicinal chemistry studies with the aim of simulating drug-likeness and bioactivity in terms of efficient binding to the target receptors. The advantages of this approach are quick outcomes, the possibility of repurposing commercially available drugs, consolidated protocols, and the availability of large databases. On the other hand, these studies do not intrinsically provide reactivity information, which requires quantum mechanical methodologies that are only applicable to significantly smaller and simplified systems at present. These latter studies focus on the drug itself, considering the chemical properties related to its structural features and motifs. Overall, such simulations provide necessary insights for a better understanding of the chemistry principles that rule the diseases at the molecular level, as well as possible mechanisms for restoring the physiological equilibrium. 517 $aFrom a Molecule to a Drug 606 $aMedicine and Nursing$2bicssc 606 $aPharmacology$2bicssc 610 $a3-chymotrypsin-like protease 610 $aaffinity chromatography 610 $aalginate 610 $aanti-ACE 610 $aanti-DPP-IV 610 $aanti-inflammatory drugs 610 $aantioxidant activity 610 $abenzoic acid derivatives 610 $abig data 610 $abinding free energy 610 $aBox-Behken 610 $abreast milk 610 $acannabinoid 610 $achemoinformatics 610 $achromatographic descriptors 610 $acisplatin 610 $aclopidogrel 610 $acoronavirus SARS-CoV-2 610 $aCOVID-19 610 $acyclooxygenase 610 $acytoprotection 610 $aDFT calculations 610 $adrug compounding 610 $adrug discovery 610 $aE-selectin 610 $aEucheuma gelatinae 610 $aextraction 610 $afucoidan 610 $agallic acid 610 $agastrointestinal digestion 610 $ahigh performance liquid chromatography 610 $aICAM-1 610 $aimine-enamine 610 $ain silico 610 $aL-selectin 610 $alithium therapy 610 $aM/P ratio 610 $aMCP-1 610 $amethadone hydrochloride 610 $amicrobiology 610 $amolecular descriptors 610 $amolecular docking 610 $amolecular dynamics 610 $amolecular dynamics simulations 610 $amonocyte migration 610 $amultitarget drug 610 $an/a 610 $anephrotoxicity 610 $aneurocytology 610 $aneuropathic pain 610 $aneuroprotection 610 $aNMR study 610 $aone-pot 610 $aoxone 610 $apain management 610 $aparamyosin 610 $aperoxymonosulfate 610 $apharmaceutical solutions 610 $apharmacodynamics 610 $apharmacokinetics 610 $aphysic-chemistry 610 $aprecision medicine 610 $aprotein binding 610 $apyrimidonic pharmaceuticals 610 $aQSAR 610 $aquercetin 610 $aquercetin 3-O-glucuronide 610 $areaction mechanism 610 $areactivity parameters 610 $arheology 610 $aSARS-CoV-2 610 $aseafood 610 $aselenium 610 $aselenoxide elimination 610 $asodium halide 610 $astability study 610 $astatistical modeling 610 $atarget fishing 610 $athienopyridine 610 $aTHP-1 macrophage 610 $atoxicology 610 $a?-carrageenan 615 7$aMedicine and Nursing 615 7$aPharmacology 700 $aRibaudo$b Giovanni$4edt$01288351 702 $aOrian$b Laura$4edt 702 $aRibaudo$b Giovanni$4oth 702 $aOrian$b Laura$4oth 906 $aBOOK 912 $a9910585940503321 996 $aFrom a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential$93020750 997 $aUNINA