LEADER 02906nam 22005413 450 001 9911007158203321 005 20250707110026.0 010 $a9781523157976 010 $a1523157976 010 $a9781774670439 010 $a1774670437 035 $a(MiAaPQ)EBC31138383 035 $a(Au-PeEL)EBL31138383 035 $a(CKB)30327228300041 035 $a(Exl-AI)31138383 035 $a(FR-PaCSA)88970941 035 $a(FRCYB88970941)88970941 035 $a(OCoLC)1422231934 035 $a(EXLCZ)9930327228300041 100 $a20240215d2024 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHandbook of Solvents, Volume 2 $eUse, Health, and Environment 205 $a4th ed. 210 1$aSan Diego :$cChemTec Publishing,$d2024. 210 4$dİ2024. 215 $a1 online resource (819 pages) 311 08$a9781774670422 311 08$a1774670429 327 $aCover -- Title page -- Copyright page -- Table of Contents -- Chapter 12. SOLVENTS USE IN VARIOUS INDUSTRIES. EXAMPLES -- 12.1 ADHESIVES AND SEALANTS -- References -- 12.2 AEROSPACE -- References -- 12.3 ASPHALT COMPOUNDING -- References -- 12.4 BIOTECHNOLOGY -- References -- 12.5 CARBON DIOXIDE CAPTURE -- References -- 12.6 CLEANING SOLVENTS AND AEROSOLS -- References -- 12.7 COIL COATING -- References -- 12.8 COLORANT SOLVENT -- References -- 12.9 COSMETICS -- References -- 12.10 DECOLORIZATION -- References -- 12.11 DRY CLEANING. TREATMENT OF TEXTILES IN SOLVENTS -- References -- 12.12 ELECTRONICS -- References -- 12.13 FABRICATED METAL PRODUCTS$7Generated by AI. 330 $aThe 'Handbook of Solvents, 4th Edition Volume 2: Use, Health, and Environment' edited by George Wypych provides a comprehensive examination of the application, health, and environmental impact of solvents across various industries. It explores the role of solvents in sectors such as adhesives, aerospace, biotechnology, cosmetics, and pharmaceuticals. The book also addresses environmental concerns, safety regulations, and the toxicological effects of solvent exposure. Intended for professionals and researchers in chemical, environmental, and industrial fields, the handbook aims to inform about the safe and effective use of solvents while highlighting emerging trends and regulatory guidelines.$7Generated by AI. 606 $aSolvents$7Generated by AI 606 $aIndustrial safety$7Generated by AI 615 0$aSolvents 615 0$aIndustrial safety 676 $a661/.807 676 $a661.807 700 $aWypych$b George$019294 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911007158203321 996 $aHandbook of Solvents, Volume 2$94392323 997 $aUNINA LEADER 07167nam 2200637 a 450 001 9910955157003321 005 20251116181733.0 010 $a1-62417-393-4 035 $a(CKB)2550000001042641 035 $a(EBL)3020458 035 $a(SSID)ssj0001177860 035 $a(PQKBManifestationID)11770979 035 $a(PQKBTitleCode)TC0001177860 035 $a(PQKBWorkID)11155952 035 $a(PQKB)10377220 035 $a(MiAaPQ)EBC3020458 035 $a(Au-PeEL)EBL3020458 035 $a(CaPaEBR)ebr10677500 035 $a(OCoLC)839699426 035 $a(BIP)42956779 035 $a(BIP)41826309 035 $a(EXLCZ)992550000001042641 100 $a20130405d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aEstrogen prevention for breast cancer /$fZsuzsanna Suba, editor 205 $a1st ed. 210 $aNew York $cNova Science Publishers$d2013 215 $a1 online resource (170 p.) 225 1 $aCancer etiology, diagnosis and treatments 300 $a"Nova biomedical." 311 08$a1-62417-378-0 320 $aIncludes bibliographical references and index. 327 $aIntro -- ESTROGEN PREVENTION FOR BREAST CANCER -- ESTROGEN PREVENTION FOR BREAST CANCER -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Acknowledgements -- Chapter I: Discovery of Estrogen Deficiency as Common Cancer Risk Factor for Highly and Moderately Estrogen Dependent Organs -- Abstract -- Introduction -- Risk Factors for Cancers of Highly Hormone Related Organs -- Controversial Associations of Hormone Replacement Therapy and Cancer Risk -- Shortcomings of Studies on the Correlations between HRT Use and Cancer Risk -- Estrogen Deficiency and Cancer Risk in Postmenopausal Women -- Moderate Estrogen Deficiency and Cancer Risk in Premenopausal Women -- Conspicuous Differences between Cancer Epidemiology of Highly and Moderately Estrogen Dependent Organs -- Extraovarian Estrogen Synthesis -- Estrogen Deficiency in Men -- Conclusion -- References -- Chapter II: Interaction between Insulin and Estrogen in the Regulation of Cell Proliferation and Carcinogenesis -- Abstract -- Introduction -- Correlations between Insulin Resistance and Cancer Risk -- Historical Review of Associations between Estrogen and Cancer Development -- Molecular Mechanism of Interplay between the Actions of Estrogen and Insulin -- Clinical Correlations between Estrogen Deficiency, Insulin Resistance and Cancer Risk -- Conclusion -- References -- Chapter III: Dose Dependent Biphasic Effect of Alcohol on Estrogen Level and Cancer Risk -- Abstract -- Introduction -- Ambiguous Biphasic Metabolic and Hormonal Effects of Moderate and Excessive Alcohol Consumption -- Associations of Alcohol Consumption, Estrogen Level and Breast Cancer Risk -- Alcohol Consumption, Hormonal Changes and Risk for Oral Cancer -- Conclusion -- References -- Chapter IV: Estrogen Level May Be Protective for Breast Cancer in Obese Women -- Abstract -- Introduction. 327 $aGrade and Distribution of Fat Deposition and Breast Cancer Risk -- Age-Related Role of Obesity in the Prediction of Breast Cancer Risk -- Effects of Reproductive Data and Menstrual Factors on Obesity-Associated Breast Cancer Risk -- Effects of Exogenous Hormone Treatment on Breast Cancer Risk -- Obesity Related Metabolic and Hormonal Disorders as Mediators of Breast Cancer Risk -- Counteraction between Obesity Associated Insulin Resistance and Protective Circulatory Estrogen Level -- Conclusion -- References -- Chapter V: Newly Recognized Player in Breast Cancer Risk: Light Deficiency -- Abstract -- Introduction -- Differences in Breast Cancer Incidence and Mortality between African-American and White American Women -- Excessive Cancer Risk of African-Americans and Dark Skinned Immigrants in Northern Geographic Regions -- Traditional Concept Concerning the Oncostatic Capacity of Melatonin Hormone -- Correlations between Excessive Melatonin Level, Other Endocrine Functions and Cancer Risk -- Correlations among Light Exposure, Melatonin Level and Breast Cancer Risk -- Conclusion -- References -- Chapter VI: Estrogen Prevention of Breast Cancer: A Critical Review -- Abstract -- Background: Randomized HRT WHI Trials -- Critique of the WHI HRT Trial Reporting -- Estrogen and the Rates of Invasive Breast Cancer -- Estrogen Benefit in Human Breast Cancer - Clinical Stage IV Breast Cancer -- Estrogen Benefit in Breast Cancer: Basic Research Data and Mechanism of Action -- Estrogen in Prevention of Breast Cancer? The Final 2000 - 2012 Reports -- Conclusion -- References -- Chapter VII: Failures and Controversies of the Antiestrogen Treatment of Breast Cancer -- Abstract -- Introduction -- Molecular Mechanisms of Estrogen Action -- Estrogen Receptors and Their Actions. 327 $aInterplay between Alpha and Beta Estrogen Receptor Isoforms in the Regulation of Cell Proliferation and of Apoptotic Cell Death -- Cross Talk between Receptor Signals of Estrogen and Growth Factors -- Estrogen Receptors and Human Cancers -- Estrogen Synthesis in Tumors -- Antiestrogen and Estrogen in Cancer Therapy -- Conclusion -- References -- Chapter VIII: Evolution of Estrogen Action in Breast Cancer: From Culprit to Killer -- Abstract -- Introduction -- Evolution of Fashions in Breast Cancer Treatment and Prevention -- Selective ER Modulation: Translation from the Laboratory to Clinical Practice -- A Roadmap to Use SERMS to Prevent Multiple Diseases in Women -- Raloxifene in Clinical Practice -- Summary of SERMs -- The Evolution of Acquired Resistance to Antihormonal Therapies -- Molecular Mechanisms of the Apoptotic Action of Estrogens -- Clinical Significance of Estrogen Induced Apoptosis -- Conclusion -- Acknowledgments -- References -- Index. 330 $aFrom the early 80s of the past century, clinical and epidemiological studies have increasingly pointed to an elevated breast, endometrial and ovarian cancer risk from high circulating estrogen levels. Estrogen deficiency as a cancer risk factor emerged first in 2007 in a study on Hungarian oral cancer cases based on the gender and age- related differences in tumor prevalence. Critical reevaluation of the contradictory results of hormone replacement therapy yielded a complete conversion that estrogen deficiency may confer cancer initiation. This book examines the deleterious interactions between estrogen deficiency and further hormonal disorders which illuminate the apparently controversial associations of obesity, light exposure and alcohol intake with breast cancer risk. 410 0$aCancer etiology, diagnosis, and treatments. 606 $aCancer$xHormone therapy 606 $aEstrogen 606 $aBreast$xCancer 615 0$aCancer$xHormone therapy. 615 0$aEstrogen. 615 0$aBreast$xCancer. 676 $a616.99/449 701 $aSuba$b Zsuzsanna$01866360 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910955157003321 996 $aEstrogen prevention for breast cancer$94473751 997 $aUNINA