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100   $a20121208d2012      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aDesigning multi-target drugs /$fedited by J. Richard Morphy, C. John Harris
205   $a1st ed.
210   $aCambridge [England] $cRSC Pub.$d2012
215   $a1 online resource (395 p.)
225  0$aRSC drug discovery series,$x2041-3203 ;$v21
300   $aDescription based upon print version of record.
311 08$a9781849733625 
311 08$a1849733627 
320   $aIncludes bibliographical references and index.
327   $ai-iv; v-x; xi-xiv; xv-xviii; xix-xxviii; 1-13; 14-31; 32-49; 50-65; 66-85; 86-93; 94-110; 111-129; 130-140; 141-154; 155-180; 181-205; 206-220; 221-242; 243-262; 263-269; 270-289; 290-315; 316-334; 335-352; 353-355; 356-366
330   $aMulti-target drug discovery (MTDD) is an emerging area of increasing interest to the drug discovery community. Drugs that modulate several targets have the potential for an improved balance of efficacy and safety compared to single targets agents. Although there are a number of marketed drugs that are thought to derive their therapeutic benefit by virtue of interacting with multiple targets, the majority of these were discovered accidentally. Written by world renowned experts, this is the first book to gather together knowledge and experiences of the rational discovery of multi-target drugs. I
410  0$aRSC Drug Discovery
606   $aDrug targeting
615  0$aDrug targeting.
676   $a615.19
701   $aMorphy$b J. Richard$01822096
701   $aHarris$b C. John$01822097
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9911007090703321
996   $aDesigning multi-target drugs$94388153
997   $aUNINA