LEADER 03302nam  2200661Ia 450 
001 9911006645003321
005 20200520144314.0
010   $a1-107-15623-8
010   $a1-280-34706-6
010   $a9786610347063
010   $a0-511-79051-1
010   $a0-511-14661-2
010   $a0-511-14603-5
010   $a0-511-14705-8
010   $a0-511-56882-7
010   $a1-60119-760-8
010   $a0-511-14647-7
024 3 $z9780521859035
035   $a(CKB)1000000000352238
035   $a(EBL)255015
035   $a(SSID)ssj0000073090
035   $a(PQKBManifestationID)11116052
035   $a(PQKBTitleCode)TC0000073090
035   $a(PQKBWorkID)10103661
035   $a(PQKB)10183344
035   $a(UkCbUP)CR9780511790515
035   $a(MiAaPQ)EBC255015
035   $a(PPN)261338552
035   $a(EXLCZ)991000000000352238
100   $a20051130d2006      uy         0
101 0 $aeng
135   $aur|||||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aSystems biology $eproperties of reconstructed networks /$fBernhard . Palsson
210   $aCambridge ;$aNew York $cCambridge University Press$d2006
215   $a1 online resource (xii, 322 pages) $cdigital, PDF file(s)
300   $aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
311   $a0-521-85903-4 
320   $aIncludes bibliographical references (p. 299-315) and index.
327   $aCover; Half-title; Title; Copyright; Dedication; Contents; Preface; CHAPTER 1 Introduction; CHAPTER 2 Basic Concepts in Systems Biology; PART ONE Reconstruction of Biochemical Networks; PART TWO Mathematical Representation of Reconstructed Networks; PART THREE Capabilities of Reconstructed Networks; APPENDIX A Nomenclature and Abbreviations; APPENDIX B Escherichia coli Core Metabolic Network; Bibliography; Index
330   $aGenome sequences are now available that enable us to determine the biological components that make up a cell or an organism. The discipline of systems biology examines how these components interact and form networks, and how the networks generate whole cell functions corresponding to observable phenotypes. This 2006 textbook devoted to systems biology describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites are some knowledge of linear algebra and biochemistry. Though the links between the mathematical ideas and biological processes are made clear, the book reflects the irreversible trend of increasing mathematical content in biology education. Therefore to assist both teacher and student, in an associated web site Palsson provides problem sets, projects and Powerpoint slides, and keeps the presentation in the book concrete with illustrative material and experimental results.
606   $aComputational biology
606   $aGenomics
606   $aBioinformatics
615  0$aComputational biology.
615  0$aGenomics.
615  0$aBioinformatics.
676   $a572.80285
700   $aPalsson$b Bernhard$0501629
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9911006645003321
996   $aSystems biology$9726520
997   $aUNINA