LEADER 05428nam 22006494a 450 001 9911006573103321 005 20230721030307.0 010 $a1-4356-1025-3 010 $a1-60119-362-9 035 $a(CKB)1000000000385082 035 $a(EBL)3382340 035 $a(SSID)ssj0000071725 035 $a(PQKBManifestationID)11969757 035 $a(PQKBTitleCode)TC0000071725 035 $a(PQKBWorkID)10090634 035 $a(PQKB)11047674 035 $a(MiAaPQ)EBC3382340 035 $a(EXLCZ)991000000000385082 100 $a20070810d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDevelopment of a biokinetic model for radionuclide-contaminated wounds and procedures for their assessment, dosimetry, and treatment$b[electronic resource] $erecommendations of the National Council on Radiation Protection and Measurements, December 14, 2006 210 $aBethesda, MD $cNational Council on Radiation Protection and Measurements$dc2007 215 $a1 online resource (428 p.) 225 1 $aNCRP report ;$vno. 156 300 $a"This report was prepared by Scientific Committee 57-17 on Radionuclide Dosimetry Model for Wounds"--Pref. 311 $a0-929600-93-2 320 $aIncludes bibliographical references (p. 346-380) and index. 327 $a""Cover""; ""Preface""; ""Contents""; ""Executive Summary""; ""1. Introduction""; ""1.1 Background""; ""1.2 Purpose and Scope""; ""2. Skin Biology""; ""2.1 Skin Anatomy""; ""2.1.1 The Epidermis""; ""2.1.2 The Dermis""; ""2.1.3 The Subcutis""; ""2.2 Binding and Transport of Injected Materials""; ""2.2.1 Loose Connective Tissue""; ""2.2.2 Tissue Fluids and Their Contents""; ""2.2.3 Connective Tissue Macrophages""; ""2.2.4 Particle Transport by Macrophages""; ""2.3 Wound Healing""; ""2.3.1 Inflammation""; ""2.3.2 Reepithelialization""; ""2.3.3 Formation of Granulation Tissue""; ""2.3.4 Burns"" 327 $a""2.3.5 Foreign-Body Reactions""""3. Etiology of Radionuclide-Contaminated Wounds""; ""3.1 Industrial Experience""; ""3.2 Military Experience with Depleted Uranium""; ""3.2.1 Introduction""; ""3.2.2 Persian Gulf War Experience""; ""3.2.3 Summary of the U.S. Department of Veterans Affairs Follow-Up Program""; ""3.2.4 Embedded Radioactive Particles and Fragments""; ""3.3 Medical Cases""; ""4. Generic Biokinetic Model for Radionuclides in Wounds""; ""4.1 Implementation of the Wound Biokinetic Model""; ""4.2 Modeling Results""; ""4.2.1 Modeling of Individual Radionuclides"" 327 $a""4.2.2 Modeling of Default Categories of Soluble Radionuclides""""4.3 Retention of Soluble Radionuclides in Other Types of Wounds: Quantitative Comparison with Intramuscular Data""; ""4.3.1 Subcutaneous Injection""; ""4.3.2 Lacerated Skin""; ""4.3.3 Abraded Skin""; ""4.3.4 Intact Skin""; ""4.3.5 Thermally-Burned Skin""; ""4.3.6 Acid-Burned Skin""; ""4.3.7 Radiation-Burned Skin""; ""4.4 Modeling of Radioactive Colloids and Particles""; ""4.4.1 Wound Retention of 239Pu4+ Hydroxide Colloids and Polymers Injected Intramuscularly in Rats and Rabbits and Subcutaneously in Dogs"" 327 $a""4.4.2 Wound Retention of 239PuO2 Particles Injected Subcutaneously in Dogs""""4.4.3 Analysis of the Retention of Other Insoluble Radioactive Particles in Wounds""; ""4.4.4 Summary for Insoluble Radionuclides""; ""4.4.5 Application of the Wound Model to Animal Data for Retention of Fine, Insoluble Radioactive Particles Deposited in Wounds""; ""4.5 Retention of Radioactive Solids in Wounds""; ""4.5.1 Depleted Uranium Metal Fragments Implanted Intramuscularly in Rats""; ""4.5.2 Plutonium Metal Wire Implanted Subcutaneously in Rabbits and Rats"" 327 $a""4.5.3 Minispheres of Nuclear Weapons Test Fallout Contaminated with Plutonium and Americium Implanted Subcutaneously in Rats""""4.5.4 Summary for Solid Radioactive Materials""; ""4.5.5 Application of the Wound Model to Animal Data for Retention of Radionuclides in Implanted Solids""; ""4.6 Default Biokinetic Parameters for Radionuclides in Wounds""; ""5. Exposure Assessment and Dosimetry of Radionuclide-Contaminated Wounds""; ""5.1 Wound Assessment""; ""5.1.1 Wound Monitors""; ""5.1.2 Survey Meters""; ""5.1.3 Sequential Measurements""; ""5.2 Local Dosimetry Models"" 327 $a""5.2.1 Skin (Shallow) Dosimetry Models"" 410 0$aNCRP report ;$vno. 156. 606 $aRadiation injuries$xTreatment$xMathematical models 606 $aRadiation dosimetry$xMathematical models 606 $aRadioisotopes$xToxicology$xMathematical models 606 $aWounds and injuries$xComplications 606 $aSkin$xEffect of radiation on 615 0$aRadiation injuries$xTreatment$xMathematical models. 615 0$aRadiation dosimetry$xMathematical models. 615 0$aRadioisotopes$xToxicology$xMathematical models. 615 0$aWounds and injuries$xComplications. 615 0$aSkin$xEffect of radiation on. 676 $a362.196/9897 712 02$aNational Council on Radiation Protection and Measurements.$bScientific Committee 57-17 on Radionuclide Dosimetry Model for Wounds. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911006573103321 996 $aDevelopment of a biokinetic model for radionuclide-contaminated wounds and procedures for their assessment, dosimetry, and treatment$94390942 997 $aUNINA