LEADER 04317nam 22007695 450 001 9910910497803321 005 20241127115237.0 010 $a9789819746125 010 $a9819746124 024 7 $a10.1007/978-981-97-4612-5 035 $a(CKB)36679664100041 035 $a(MiAaPQ)EBC31806124 035 $a(Au-PeEL)EBL31806124 035 $a(DE-He213)978-981-97-4612-5 035 $a(OCoLC)1474240851 035 $a(EXLCZ)9936679664100041 100 $a20241127d2024 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aProstate Cancer: Molecular Events and Therapeutic Modalities /$fedited by Gautam Sethi, Milad Ashrafizadeh, Nasim Ebrahimi 205 $a1st ed. 2024. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024. 215 $a1 online resource (290 pages) 311 08$a9789819746118 311 08$a9819746116 327 $aChapter 1. Anatomy and function of prostate -- Chapter 2. Epidemiology, risk factors and histopathological profile of prostate cancer -- Chapter 3. Prostate cancer and Inflammation -- Chapter 4. Prostate cancer, apoptosis, autophagy and ferroptosis: Cell death mechanisms and their crosstalk -- Chapter 5. Prostate cancer and metastasis: An emphasis on EMT mechanism -- Chapter 6. Prostate cancer and Wnt/STAT3 signaling -- Chapter 7. Prostate cancer and EZH2 signaling -- Chapter 8. Prostate cancer and PTEN/PI3K/Akt/mTOR signaling -- Chapter 9. Prostate cancer and non-coding RNAs: A focus on miRNAs, lncRNAs and circRNAs -- Chapter 10. Prostate cancer and tumor microenvironment -- Chapter 11. Chemoresistance, radioresistance and androgen-deprivation therapy resistance in prostate cancer -- Chapter 12. Plant derived-natural products in treatment of prostate cancer -- Chapter 13. Gene therapy as a new emerging strategy for prostate cancer -- Chapter 14. Nanoparticle-based therapeutic strategies in prostate cancer suppression. 330 $aThe book covers the various cell signaling pathways responsible for prostate cancer progression, conventional therapies used for prostate cancer treatment, new emerging therapeutics, and challenges in the treatment of cancer patients. It describes the different molecular pathways responsible for prostate cancer progression to improve readers' knowledge about the role of signaling networks, and cellular and molecular aspects of prostate cancer progression. These topics include mechanisms responsible for prostate cancer malignancy with a focus on molecular pathways. It also discusses the current challenges in prostate cancer treatment such as drug resistance and immune evasion and introduces novel therapeutics such as gene therapy and nanotherapeutics for prostate cancer. This book is completely novel and unique and covers all aspects of prostate cancer progression and challenges in therapy while presenting solutions. Written by prestigious researchers around the world, this book will be interesting to researchers and practitioners, especially those working in urological cancers. 606 $aCancer$xTreatment 606 $aMedical genetics 606 $aCancer 606 $aNanomedicine 606 $aOncology 606 $aEpidemiology 606 $aGenetics$xResearch 606 $aCancer Therapy 606 $aClinical Genetics 606 $aCancer Nanotechnology 606 $aOncology 606 $aEpidemiology 606 $aGenetics Research 615 0$aCancer$xTreatment. 615 0$aMedical genetics. 615 0$aCancer. 615 0$aNanomedicine. 615 0$aOncology. 615 0$aEpidemiology. 615 0$aGenetics$xResearch. 615 14$aCancer Therapy. 615 24$aClinical Genetics. 615 24$aCancer Nanotechnology. 615 24$aOncology. 615 24$aEpidemiology. 615 24$aGenetics Research. 676 $a616.9946306 700 $aSethi$b Gautam$01777044 701 $aAshrafizadeh$b Milad$01777045 701 $aEbrahimi$b Nasim$01777046 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910910497803321 996 $aProstate Cancer: Molecular Events and Therapeutic Modalities$94296450 997 $aUNINA LEADER 03592nam 2200529Ia 450 001 9911006534303321 005 20200520144314.0 010 $a0-7844-7701-9 010 $a0-7844-1253-7 035 $a(CKB)2670000000349339 035 $a(EBL)3115633 035 $a(SSID)ssj0000871693 035 $a(PQKBManifestationID)12426576 035 $a(PQKBTitleCode)TC0000871693 035 $a(PQKBWorkID)10822788 035 $a(PQKB)11297054 035 $a(MiAaPQ)EBC3115633 035 $a(ASCE)10.1061/9780784412534 035 $a(EXLCZ)992670000000349339 100 $a20120814d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aInland navigation $echannel training works /$fprepared by the Task Committee on Inland Navigation of the Waterways Committee of the Coasts, Oceans, Ports, and Rivers Institute of the American Society of Civil Engineers ; edited by Thomas J. Pokrefke 210 $aReston, VA $cAmerican Society of Civil Engineers$dc2012 215 $a1 online resource (188 p.) 225 0 $aASCE manuals and reports on engineering practice ;$vno. 124 300 $aDescription based upon print version of record. 320 $aIncludes bibliographical references and index. 327 $aIntroduction; Sedimentation and Sediment Management in River Channels; History; Training Structure Types and Layout; Dikes; Revetments; Other Types of Training Structures; Case Studies; Cost; Environmental Design; Model Studies; Performance, Evaluation, and Inspection; Repair Techniques; Terminology; Development of Channel Contraction Widths; Index 330 3 $aPrepared by the Task Committee on Inland Navigation of the Waterways Committee of the Coasts, Oceans, Ports, and Rivers Institute of ASCE. Inland Navigation: Channel Training Works presents design guidance on structures that reshape a river channel to create reliable depths and widths for safe and dependable vessel transit. This Manual of Practice focuses on training structures used in open-river channels with flow in one direction (non-tidal), and many of the structures are also appropriate for use on low-head (no reservoir storage capacity) lock-and-dam river systems. It describes in detail the proper use of dikes and revetments and explains how to design channel dimensions and alignment so that little or no maintenance dredging is required. Topics include: sediment management in river channels; evolution of training works in the United States; training structure types and layout; dikes; revetments; other types of training works; case studies; costs; environmental design; model studies; performance evaluation and inspection; repair techniques. Includes a glossary and a reprint of a 1991 paper on an analytical method to determine dike length. MOP 124 is a key reference for navigation engineers working on U.S. Army Corps of Engineers projects or in the private sector, as well as state and local government officials charged with managing river systems. 606 $aInland navigation$zUnited States 606 $aStream channelization$zUnited States 615 0$aInland navigation 615 0$aStream channelization 676 $a627/.12 701 $aPokrefke$b Thomas J$01824321 712 02$aCoasts, Oceans, Ports and Rivers Institute (American Society of Civil Engineers).$bTask Committee on Inland Navigation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911006534303321 996 $aInland navigation$94391435 997 $aUNINA