LEADER 05363nam 2200649Ia 450 001 9911006524503321 005 20200520144314.0 010 $a1-282-48172-X 010 $a9786612481727 010 $a0-8155-2026-3 010 $a0-08-095187-2 035 $a(CKB)2560000000004117 035 $a(EBL)535187 035 $a(OCoLC)635293558 035 $a(SSID)ssj0000386335 035 $a(PQKBManifestationID)11291705 035 $a(PQKBTitleCode)TC0000386335 035 $a(PQKBWorkID)10399376 035 $a(PQKB)11549495 035 $a(MiAaPQ)EBC535187 035 $a(PPN)182566722 035 $a(EXLCZ)992560000000004117 100 $a20090625d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHandbook of non-invasive drug delivery systems $escience and technology /$fVitthal S. Kulkarni 205 $a1st ed. 210 $aNorwich, N.Y. $cWilliam Andrew ;$aOxford $cElsevier Science [distributor]$d2009 215 $a1 online resource (327 pages) 225 1 $aPersonal Care and Cosmetic Technology 311 0 $a0-8155-2025-5 327 $aFront Cover; Handbook of NON-INVASIVE DRUG DELIVERY SYSTEMS; Copyright; CONTENTS; PREFACE; EDITOR BIOGRAPHY; CONTRIBUTORS; ACKNOWLEDGEMENT; CHAPTER 1Topical and Transdermal Drug Delivery; 1.1 STRUCTURE OF THE SKIN; 1.2 TOPICAL vs. TRANSDERMAL DRUG DELIVERY; 1.3 PERCUTANEOUS ABSORPTION PATHWAYS; 1.4 APPROACHES TO ENHANCE PASSIVE CUTANEOUSDRUG ABSORPTION; 1.5 CONCLUSIONS; REFERENCES; CHAPTER 2 Micellar Nanoparticles: Applications for Topical and Passive Transdermal Drug Delivery; 2.1 INTRODUCTION; 2.2 TRANSDERMAL DRUG DELIVERY APPLICATIONS OF MNPTECHNOLOGY 327 $a2.3 TOPICAL DRUG DELIVERY APPLICATIONS OF MNPTECHNOLOGY; 2.4 CONCLUSION; REFERENCES; CHAPTER 3Emulsions and Microemulsions for Topical and Transdermal Drug Delivery; 3.1 OVERVIEW OF BASIC ASPECTS OF EMULSIONSAND MICROEMULSIONS; 3.2 APPLICATION OF EMULSIONS FOR TOPICALAND TRANSDERMAL DRUG DELIVERY; 3.3 ADVANCES IN USING MICROEMULSIONS AS TOPICALAND TRANSDERMAL DRUG DELIVERY SYSTEMS; REFERENCES; CHAPTER 4Iontophoretic Transdermal Drug Delivery; 4.1 INTRODUCTION; 4.2 HISTORY AND DEVELOPMENT OF IONTOPHORESIS; 4.3 ADVANTAGES AND LIMITATIONS OF IONTOPHORESIS 327 $a4.4 IONTOPHORETIC DELIVERY PRINCIPLES AND SYSTEM COMPONENTS; 4.5 DRUG TRANSPORT IN IONTOPHORESIS; 4.6 PATHWAYS FOR IONTOPHORETIC TRANSPORTAND FACTORS AFFECTING THE SAME; 4.7 PROPERTIES OF THE DRUG/ION: CONCENTRATION,COMPETING IONS, AND MOLECULAR SIZE; 4.8 PROPERTIES OF THE IONTOPHORETIC SYSTEM: pH, CURRENT; 4.9 COMBINATION STRATEGIES TO IMPROVETRANSDERMAL IONTOPHORETIC DRUG DELIVERY; 4.10 REVERSE IONTOPHORESIS; 4.11 APPLICATIONS OF IONTOPHORESIS; 4.12 CURRENT AND FUTURE DEVELOPMENT; REFERENCES; CHAPTER 5 Ultrasound-based Technology for Skin Barrier Permeabilization; 5.1 INTRODUCTION 327 $a5.2 WHAT IS ULTRASOUND?; 5.3 ULTRASOUND BIOEFFECTS; 5.4 HISTORICAL BACKGROUND; 5.5 SONOPHORESIS FOR ENHANCED DRUG DELIVERY; 5.6 ONGOING DEVELOPMENTS; 5.7 CURRENT CHALLENGES AND TRENDS; REFERENCES; CHAPTER 6Microneedles - Minimally Invasive Transdermal Delivery Technology; 6.1 INTRODUCTION; 6.2 MICRONEEDLE GEOMETRY; 6.3 TYPES OF APPROACH; 6.4 FACTORS INFLUENCING TRANSDERMAL PERMEATION; 6.5 MICRONEEDLE TECHNOLOGY IN DRUG DELIVERY; 6.6 COMMERCIALIZATION OF MICRONEEDLE TECHNOLOGY; 6.7 CONCLUSION; REFERENCES; CHAPTER 7 Recent Advances in Ophthalmic Drug Delivery; 7.1 INTRODUCTION 327 $a7.2 THE ANATOMY OF THE EYE; 7.3 DELIVERY SYSTEMS FOR THE ANTERIOR SEGMENT; 7.4 RETINAL DRUG DELIVERY SYSTEMS; 7.5 CONCLUSIONS; REFERENCES; CHAPTER 8 Nasal Delivery of Micro- and Nano-encapsulated Drugs; 8.1 INTRODUCTION; 8.2 PHYSIOLOGY OF THE NOSE; 8.3 DRUG DELIVERY FORMULATION; 8.4 MICRO- AND NANO-ENCAPSULATION; 8.5 SUMMARY; REFERENCES; CHAPTER 9 Pulmonary Drug Delivery; 9.1 GENERAL INTRODUCTION; 9.2 PULMONARY DRUG DEPOSITION MECHANISMS; 9.3 PULMONARY DRUG DELIVERY METHODS; 9.4 ANALYTICAL METHODS; 9.5 CHALLENGES AND ADVANTAGES; 9.6 CONCLUSIONS; REFERENCES; CHAPTER 10 Regulatory Aspects of Nasal and Pulmonary Spray Drug; nbsp; Products 330 $aWith the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery. The Handbook of Non-Invasive Drug Delivery Systems encompasses the broad field of non-invasive drug delivery systems that include drug delivery via topical, transdermal-passive, transdermal-active (device- aided enhanced penetration), trans-mucosal membrane, trans-ocular membrane as well as delivery via alveolar membrane from inhaled medication. Patient complianc 410 0$aPersonal Care and Cosmetic Technology 606 $aDrug delivery systems 606 $aTransdermal medication 606 $aOral medication 615 0$aDrug delivery systems. 615 0$aTransdermal medication. 615 0$aOral medication. 676 $a615.6 676 $a615.6 700 $aKulkarni$b Vitthal S$01724104 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911006524503321 996 $aHandbook of non-invasive drug delivery systems$94388975 997 $aUNINA