LEADER 02792nam 2200721 a 450 001 9911004820703321 005 20200520144314.0 010 $a9781628701395 010 $a1628701390 010 $a9781847555304 010 $a1847555306 035 $a(CKB)1000000000791710 035 $a(EBL)1186086 035 $a(OCoLC)229137260 035 $a(SSID)ssj0000379650 035 $a(PQKBManifestationID)11258116 035 $a(PQKBTitleCode)TC0000379650 035 $a(PQKBWorkID)10371657 035 $a(PQKB)10028599 035 $a(MiAaPQ)EBC1186086 035 $a(PPN)198474806 035 $a(MiAaPQ)EBC7425044 035 $a(Au-PeEL)EBL7425044 035 $a(Perlego)787522 035 $a(EXLCZ)991000000000791710 100 $a20070109d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSequence-specific DNA binding agents /$fedited by Michael Waring 205 $a1st ed. 210 $aCambridge $cRSC Pub.$dc2006 215 $a1 online resource (271 p.) 225 0$aRSC biomolecular sciences 300 $aDescription based upon print version of record. 311 08$a9780854043705 311 08$a0854043705 320 $aIncludes bibliographical references and index. 327 $aSequence-specific DNA Binding Agents; i_iv; v_vi; vii_xii; 001_028; 029_043; 044_068; 069_095; 096_108; 109_129; 130_151; 152_189; 190_206; 207_232; 233_252; 253_258 330 $aThe binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the subject. Written by experts in the field, this book discusses diverse modes of binding of antibiotics and drugs to DNA, emphasising matters that are important or promising for cancer treatment. Chapters discuss established agents like actinomycin D but also look at novel drugs with strong potential in chemotherapy suc 410 0$aRSC Biomolecular Sciences 606 $aDNA-drug interactions 606 $aDNA-binding proteins 606 $aGene targeting 606 $aDrug targeting 606 $aChemotherapy 615 0$aDNA-drug interactions. 615 0$aDNA-binding proteins. 615 0$aGene targeting. 615 0$aDrug targeting. 615 0$aChemotherapy. 676 $a616.994061 701 $aWaring$b Michael J$0728341 712 02$aRoyal Society of Chemistry (Great Britain) 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911004820703321 996 $aSequence-specific DNA binding agents$94389615 997 $aUNINA