LEADER 03719nam 22006495 450 001 9910999792903321 005 20250429130221.0 010 $a3-031-85881-6 024 7 $a10.1007/978-3-031-85881-9 035 $a(CKB)38641751500041 035 $a(DE-He213)978-3-031-85881-9 035 $a(MiAaPQ)EBC32062816 035 $a(Au-PeEL)EBL32062816 035 $a(EXLCZ)9938641751500041 100 $a20250429d2025 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNutrigenomics $eHow Science Works /$fby Carsten Carlberg, Ferdinand Molnár 205 $a2nd ed. 2025. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2025. 215 $a1 online resource (XX, 220 p. 102 illus., 101 illus. in color.) 311 08$a3-031-85880-8 327 $aNutrition's Role in Health and Disease -- Diet Driven Genetic Adaptations of Modern Humans -- Mechanisms of Nutrient Detection and Nuclear Receptors -- Interplay Between Environment, Diet, and Genome -- Nutritional Epigenetics -- Nutrition and Aging -- Nutrition and Immune Responses -- Nutrition and Cancer -- Obesity -- Insulin Resistance and Diabetes -- CVD and Metabolic Syndrome. 330 $aNow in its second edition, this concise textbook provides an overview of the field of nutrigenomics, a topic at the intersection of nutrition and genetics that explores how dietary molecules interact with our genome and epigenome to influence health and disease. Substantially updated and expanded, the book offers a fresh perspective on how diet has shaped human evolution and our susceptibility to conditions such as type 2 diabetes and cardiovascular disease. The 11 chapters cover a wide range of topics, beginning with an overview of the role of nutrients in health and disease, basic mechanisms of nutrient sensing and nuclear receptors, and the impact of epigenetic regulation on health. Readers will discover how chromatin-modifying enzymes and energy status-sensing kinases play critical roles in signaling pathways between diet and the genome. The book also explores the influence of diet on cancer prevention, the importance of the microbiome, and low-grade chronic inflammation and aging. Written in an accessible style, this textbook is intended for undergraduate and graduate students in nutrition, biochemistry, molecular biology, and biology as well as for students and practitioners in medicine. Numerous color illustrations aid in the transfer of knowledge by graphically summarizing complex processes. Combined with a glossary that explains key terms, this work is an indispensable resource for anyone interested in how our daily dietary choices interact with our genome. 606 $aMedical genetics 606 $aNutrition 606 $aEpigenetics 606 $aCytology 606 $aMetabolism 606 $aMedical Genetics 606 $aNutrition 606 $aEpigenetics 606 $aCell Biology 606 $aMetabolism 615 0$aMedical genetics. 615 0$aNutrition. 615 0$aEpigenetics. 615 0$aCytology. 615 0$aMetabolism. 615 14$aMedical Genetics. 615 24$aNutrition. 615 24$aEpigenetics. 615 24$aCell Biology. 615 24$aMetabolism. 676 $a616.042 700 $aCarlberg$b Carsten$4aut$4http://id.loc.gov/vocabulary/relators/aut$0849346 702 $aMolna?r$b Ferdinand$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910999792903321 996 $aNutrigenomics$92509301 997 $aUNINA