LEADER 03759nam 22005655 450 001 9910999787903321 005 20250417130324.0 010 $a3-662-70745-4 024 7 $a10.1007/978-3-662-70745-6 035 $a(CKB)38485089400041 035 $a(DE-He213)978-3-662-70745-6 035 $a(MiAaPQ)EBC32012001 035 $a(Au-PeEL)EBL32012001 035 $a(EXLCZ)9938485089400041 100 $a20250417d2025 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMastering the Patch Clamp Technique: A Practical Guide /$fby Fabian Christoph Roth, Markus Numberger, Andreas Draguhn 205 $a1st ed. 2025. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2025. 215 $a1 online resource (XIV, 162 p. 43 illus., 20 illus. in color.) 311 08$a3-662-70744-6 327 $aThe History of the Patch Clamp Technique -- Bioelectrical Phenomena and their Measurement -- Technical Basics of the Patch Clamp Method -- The Patch Clamp Rig and Technical Components -- The Practice of Patch Clamp Experiments -- Special Applications -- Data Handling and Documentation. 330 $aThe patch clamp technique is one of the most important electrophysiological methods in use today. Its application in basic biomedical research has provided significant insights into the function and properties of ion channels, making it equally indispensable in applied pharmacological research. This book is the English edition of the popular German introduction to the patch clamp technique. This introductory book serves as a practical guide for teachers and students, offering clear and practical instructions on patch clamp recordings. The authors provide essential information to establish and successfully apply this method in the laboratory. The book covers the basics of measurements, the detailed setup of a patch clamp rig and how to carry out typical recordings. It also includes concrete tips and tricks to help with troubleshooting, making it an indispensable resource. The book not only highlights the enormous potential of the method for the study of ion channels and cell signaling, but also provides an introduction to the major developments and variations of the technique. The book is aimed at advanced students of biology, biochemistry, medicine, pharmacy and related disciplines as well as scientists who want to better understand and/or acquire the technique. About the Authors Fabian Roth is a neurobiologist who researches and teaches at the Institute of Basic Medical Sciences (IMB) at the University of Oslo, Norway. Markus Numberger is a biologist and works as a freelance science writer in the fields of medicine, pharmacy and biology. Andreas Draguhn is a medical doctor and lecturer at the University of Heidelberg, Germany. 606 $aNeurosciences 606 $aCytology 606 $aMolecular biology 606 $aNeuroscience 606 $aCell Biology 606 $aMolecular Biology 615 0$aNeurosciences. 615 0$aCytology. 615 0$aMolecular biology. 615 14$aNeuroscience. 615 24$aCell Biology. 615 24$aMolecular Biology. 676 $a612.8 700 $aRoth$b Fabian Christoph$4aut$4http://id.loc.gov/vocabulary/relators/aut$01817599 702 $aNumberger$b Markus$4aut$4http://id.loc.gov/vocabulary/relators/aut 702 $aDraguhn$b Andreas$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910999787903321 996 $aMastering the Patch Clamp Technique: A Practical Guide$94375507 997 $aUNINA LEADER 01063nam0 22002651i 450 001 UON00307934 005 20231205104042.313 010 $a85-7402-720-0 100 $a20080212d2006 |0itac50 ba 101 $apor 102 $aBR 105 $a|||| ||||| 200 1 $aAntologia comentada da poesia brasileira do século 21$fManuel da Costa Pinto. Sao Paulo$ePublifolha, 2006 210 $a382 p.$a22 cm. 606 $aLetteratura brasiliana$xAntologie$3UONC041508$2FI 620 $aBR$dSão Paulo$3UONL002145 676 $a869.9$cLetteratura brasiliana. Biografia. Critica$v21 700 1$aPINTO$bManuel da Costa$3UONV181678$0696938 712 $aPublifolha$3UONV274889$4650 801 $aIT$bSOL$c20251107$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00307934 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI VIII 029 $eSI DA 2011 5 029 996 $aAntologia comentada da poesia brasileira do século 21$91376585 997 $aUNIOR