LEADER 03041nam 22005655 450 001 9910987788703321 005 20250708000247.0 010 $a981-9757-42-8 024 7 $a10.1007/978-981-97-5742-8 035 $a(CKB)37916648100041 035 $a(DE-He213)978-981-97-5742-8 035 $a(MiAaPQ)EBC31959371 035 $a(Au-PeEL)EBL31959371 035 $a(EXLCZ)9937916648100041 100 $a20250313d2025 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPreclinical cancer models for translational research and drug development /$fedited by Suresh P.K., Arindam Banerjee 205 $a1st ed. 2025. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2025. 215 $a1 online resource (XI, 168 p. 51 illus., 50 illus. in color.) 311 08$a981-9757-41-X 327 $aPreclinical Models for Cancer Research and Development.-Insight on the Current Advancements in the Diagnosis and Treatment of Head and Neck Cancer -- The role of oral cancer heterogeneity in therapies in various cellular and preclinical models -- In-depth analysis of Self-assembled in-vitro spheroidal and organoid systems -- Preclinical in vivo animal xenograft models -- Heterogeneity and biomarkers of therapeutic response and resistance -- Higher Order in vitro Models of dysregulated bioenergetics mechanisms and drug development -- In Silico Strategies for Cancer Model Development and Anticancer Drug Testing. 330 $aThis book provides updated information on certain in vitro and preclinical in vivo cancer models. The topics covered include an update on advancements in the diagnosis, treatment and heterogeneity in certain cancers; the development of preclinical in vitro and xenograft-based in vivo cancer models as well as their validation based on widely-accepted biomarkers; modelling of aberrations in bioenergetics in cancers. Also, the importance and latest advances of in silico modeling for the design of new and potent anti-cancer drugs has been reviewed. Cutting-edge and resourceful, this book is valuable for researchers, academicians, and professionals involved in cancer research. 606 $aCancer 606 $aCancer$xAnimal models 606 $aTumor markers 606 $aCancers 606 $aCancer Models 606 $aTumour Biomarkers 615 0$aCancer. 615 0$aCancer$xAnimal models. 615 0$aTumor markers. 615 14$aCancers. 615 24$aCancer Models. 615 24$aTumour Biomarkers. 676 $a571.978 676 $a616.994 702 $aP.K$b Suresh$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBanerjee$b Arindam$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910987788703321 996 $aPreclinical cancer models for translational research and drug development$94337474 997 $aUNINA