LEADER 04886nam 22007215 450 001 9910986135903321 005 20250306115249.0 010 $a9783031844416$b(electronic bk.) 010 $z9783031844409 024 7 $a10.1007/978-3-031-84441-6 035 $a(MiAaPQ)EBC31946516 035 $a(Au-PeEL)EBL31946516 035 $a(CKB)37783640400041 035 $a(DE-He213)978-3-031-84441-6 035 $a(OCoLC)1507697997 035 $a(EXLCZ)9937783640400041 100 $a20250306d2025 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAssessing Human Exposure to Key Chemical Carcinogens $eDiagnostic Approaches and Interpretation /$fby Vladan Radosavljevic 205 $a1st ed. 2025. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2025. 215 $a1 online resource (220 pages) 311 08$aPrint version: Radosavljevic, Vladan Assessing Human Exposure to Key Chemical Carcinogens Cham : Springer,c2025 9783031844409 327 $aIntroduction -- Arsenic -- Cadmium -- Nickel -- Beryllium -- Chromium hexavalent -- Aflatoxins -- 4- Aminobiphenyl -- Aristolochic acids -- Benzene -- Benzidine -- Benzo[a]pyrene.-Bis(chloromethyl) ether (BHME) and Chloromethyl methyl ether (HMME) -- 1,3-Butadiene -- Vinyl chloride -- 1,2-dichloropropane -- Ethylene oxide -- Lindane (gamma hexachlorocyclohexane ? ?-HHCH) -- 4,4'-methylenebis(2-chloroaniline) -- 2-naphthylamine (2-NA) -- Orthotoluidine -- Pentachlorophenol -- Polychlorinated biphenyls (PHBs) -- Polycyclic aromatic hydrocarbons (shale oil) -- Polycyclic aromatic hydrocarbons (soot) -- Polycyclic aromatic hydrocarbons (coke production) -- Polycyclic aromatic hydrocarbons (occupational exposure during coal tar distillation) -- Polycyclic aromatic hydrocarbons (emissions from burning coal indoors) -- 2,3,7,8-Tetrachlorodibenzo-para-dioxin -- 2,3,4,7,8-Pentachlorodibenzofuran -- Trichlorethylene. 330 $aThis book introduces an effective, affordable, non-invasive, and quick method to detect exposure to dangerous chemical carcinogens, which cause life-threatening conditions like cardiovascular, endocrine, neurological, hematological, dermatological, and malignant diseases. Nearly 20 million people are diagnosed with cancer annually, with almost 10 million deaths. While eliminating carcinogens completely is impossible, improving detection and monitoring?especially through specialized urine analysis?can help define preventive measures to lower carcinogen levels in the body. The chemical carcinogens discussed have been used for decades without proper evaluation of their health effects, costing millions of lives. Considering the long-term health impacts of current products is critical. Early detection is crucial as most carcinogens have cumulative effects. Identifying urinary markers of exposure can help detect, eliminate, or reduce sources of carcinogens, advancing preventive oncology. The book focuses on Group 1 chemical carcinogens classified by the International Agency for Research on Cancer (IARC). The described methods are highly effective, affordable, and applicable in any location with HPLC (High-Performance Liquid Chromatography) and ICP (Inductively Coupled Plasma) devices. They are non-invasive, requiring only urine samples, quick, and inexpensive. This volume aims to develop, improve, and implement screening methods for malignant diseases. It supports medical professionals in interpreting HPLC and ICP urinary analyses and providing guidance on reducing or avoiding carcinogen exposure. In some cases, doctors may identify sources of exposure and inform authorities to address and eliminate these hazards. 606 $aOncology 606 $aCancer$xPrevention 606 $aHematology 606 $aToxicology 606 $aMedicine, Preventive 606 $aHealth promotion 606 $aEndocrinology 606 $aOncology 606 $aCancer Prevention 606 $aHematology 606 $aMedical Toxicology 606 $aHealth Promotion and Disease Prevention 606 $aEndocrinology 615 0$aOncology. 615 0$aCancer$xPrevention. 615 0$aHematology. 615 0$aToxicology. 615 0$aMedicine, Preventive. 615 0$aHealth promotion. 615 0$aEndocrinology. 615 14$aOncology. 615 24$aCancer Prevention. 615 24$aHematology. 615 24$aMedical Toxicology. 615 24$aHealth Promotion and Disease Prevention. 615 24$aEndocrinology. 676 $a616.994 700 $aRadosavljevic$b Vladan$01752919 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910986135903321 996 $aAssessing Human Exposure to Key Chemical Carcinogens$94327441 997 $aUNINA