LEADER 00863nam0-22003011i-450- 001 990000277360403321 005 20001010 035 $a000027736 035 $aFED01000027736 035 $a(Aleph)000027736FED01 035 $a000027736 100 $a20001010d--------km-y0itay50------ba 101 0 $aita 105 $ay-------001yy 200 1 $aNonlinear Programming Analysis and Methodes$fMordecai Avriel. 210 $aEnglewood Cliffs$cPrentice-Hall$d1976 215 $aXV,512 p., 24 cm 225 1 $aPrentice-Hall series in automatic computation 676 $a519 700 1$aAvriel,$bMordecai$014366 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990000277360403321 952 $a04 022-70$bIRC 947/L$fDINCH 959 $aDINCH 996 $aNonlinear Programming Analysis and Methodes$9119674 997 $aUNINA DB $aING01 LEADER 03893nam 22007455 450 001 9910983348603321 005 20250108115241.0 010 $a9783031766688 010 $a3031766687 024 7 $a10.1007/978-3-031-76668-8 035 $a(CKB)37178048200041 035 $a(MiAaPQ)EBC31876217 035 $a(Au-PeEL)EBL31876217 035 $a(DE-He213)978-3-031-76668-8 035 $a(OCoLC)1484013517 035 $a(EXLCZ)9937178048200041 100 $a20250108d2025 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEvolution of Bioenergetics from Elements to Life $eEmergence of High Energy Mitochondria /$fby David F. Stowe 205 $a1st ed. 2025. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Springer,$d2025. 215 $a1 online resource (350 pages) 311 08$a9783031766671 311 08$a3031766679 327 $aChapter 1 Elements of the cosmos as precursors for lifeforms -- Chapter 2 Light metal ions and oxyanions as current carriers for early lifeforms -- Chapter 3 Origin of complex biomolecules on the dawn of lifeforms -- Chapter 4 Genesis of mitochondria to power complex lifeforms -- Chapter 5 Mitochondrial function and bioenergetics -- Chapter 6 Process of oxidative phosphorylation and free radical generation -- Chapter 7 Ionic and molecular regulation of mitochondrial bioenergetics -- Chapter 8 Regulation of bioenergetics in cardiac myocytes -- Chapter 9 Physiology and evolution of the heart. 330 $aThis book begins with the creation of the elements used in life and how these elements, as atoms, bound together into organic compounds and polymerized into lipids, peptides, and nucleotides. The text stresses the role and importance of the elements C, H, O, N, P, S, the univalent and multivalent ions, and the requirement of liquid water to foster prebiotic life. Expert author Dr. David Stowe explains the role of early molecular interactions in developing the first living prokaryote bacteria and their eventual engulfment as organelles to make eukaryotes that allowed their sophistication into specialized cells and large multicellular organisms. The book uniquely traces the genesis of bioenergetics and uses cardiac cell mitochondia as an evolutionary example for modern bioenergetic function. This book is geared toward graduate students, post-doctoral fellows, and other academics interested in evolutionary biochemistry with an emphasis on the early development of bioenergetics leading to modern, high energy mitochondria. 606 $aBiochemistry 606 $aEvolution (Biology) 606 $aCardiovascular system 606 $aPhysiology 606 $aEvolutionary developmental biology 606 $aDevelopmental biology 606 $aBlood-vessels$xGrowth 606 $aBiochemistry 606 $aEvolutionary Biology 606 $aCardiovascular Physiology 606 $aEvolutionary Developmental Biology 606 $aDevelopmental Biology and Stem Cells 606 $aAngiogenesis 615 0$aBiochemistry. 615 0$aEvolution (Biology) 615 0$aCardiovascular system. 615 0$aPhysiology. 615 0$aEvolutionary developmental biology. 615 0$aDevelopmental biology. 615 0$aBlood-vessels$xGrowth. 615 14$aBiochemistry. 615 24$aEvolutionary Biology. 615 24$aCardiovascular Physiology. 615 24$aEvolutionary Developmental Biology. 615 24$aDevelopmental Biology and Stem Cells. 615 24$aAngiogenesis. 676 $a572 700 $aStowe$b David F$01785250 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910983348603321 996 $aEvolution of Bioenergetics from Elements to Life$94316833 997 $aUNINA