LEADER 01065nam0-2200361---450- 001 990009924950403321 005 20141211181852.0 010 $a978-3-642-05708-3 035 $a000992495 035 $aFED01000992495 035 $a(Aleph)000992495FED01 035 $a000992495 100 $a20141211d--------km-y0itay50------ba 101 1 $aeng 102 $aDE 105 $aa---a---001yy 200 1 $aElectric contacts$etheory and applications$fRagnar Holm$gwith a new preface by J. Brian, P. Williamson 210 $aBerlin [etc.]$cSpringer$d2010 215 $aXV, 482 p.$cill.$d24 cm 305 $aReprint of the 4. completely rewritten edition 1967, 3rd printing 2000 610 0 $aElettricitą 610 0 $aMagnetism 610 0 $aCampi elettromagnetici 700 1$aHolm,$bRagnar$0524290 702 1$aBrian,$bJ. 702 1$aWilliamson,$bP. 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990009924950403321 952 $a29-194$bDIPFIS 254$fFI1 959 $aFI1 996 $aElectric contacts$9830205 997 $aUNINA LEADER 04989nam 22007455 450 001 9910980481403321 005 20250215115514.0 010 $a9789819602179 010 $a9819602173 024 7 $a10.1007/978-981-96-0217-9 035 $a(MiAaPQ)EBC31909067 035 $a(Au-PeEL)EBL31909067 035 $a(CKB)37548342000041 035 $a(DE-He213)978-981-96-0217-9 035 $a(OCoLC)1500763675 035 $a(EXLCZ)9937548342000041 100 $a20250215d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAsthma-COPD Overlap $eUpdated Concept, Pathophysiology, Diagnosis and Treatment /$fedited by Hiroyuki Nagase, Hisatoshi Sugiura, Toshihiro Shirai 205 $a1st ed. 2024. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024. 215 $a1 online resource (336 pages) 225 1 $aRespiratory Disease Series: Diagnostic Tools and Disease Managements,$x2509-5560 311 08$a9789819602162 311 08$a9819602165 327 $aPart 1 Concept of Asthma COPD overlap -- 1 Concept of Asthma COPD overlap - Japanese guideline and global trends. How was the concept of Asthma COPD overlap developed and moving forward? -- 2 Concept of treatable traits and ACO (2): Can treatable traits approach be applied into practice? -- Part 2 Epidemiology and Prognosis -- 3 Epidemiology of ACO from global data: Does the prevalence of ACO vary among global analyses? -- 4 Epidemiology of ACO defined by the JRS guidelines. What is the prevalence of ACO in Japan? -- 5 Prognosis and characteristics of ACO: What are the specific characteristics of ACO?- 6 Prognosis of COPD with asthma-like features and ACO: Is the prognosis of COPD and ACO different? -- 7 Causes of death in patients with asthma-chronic obstructive pulmonary disease overlap: Is there any difference compared to asthma? -- Part 3 Pathophysiology of ACO -- 8 Inflammatory phenotypes and potential bio-markers of ACO. What is the specific feature of ACO? -- 9 Role of Nitrosative stress: What is the potential clinical implication? -- 10 Radiographic features of ACO. How the feature is applied into practice? -- 11 Pulmonary Function of ACO: What is the role of the forced oscillation technique? -- 12 Underlying mechanism suggested by the ACO model. What is the lesson learned from the model? -- Part 4 Diagnosis of ACO -- 13 Comparison of diagnostic criteria of ACO: What is the point of difference? -- 14 Role of FeNO - How can FeNO be positioned in practice? -- 15 Role of IgE and Eosinophils: The use of type 2 biomarkers in practice -- 16 Rhinosinusitis in ACO: What is the implication of nasal comorbidity? -- Part 5 Treatment -- 17 Current evidence of treatment for asthma-COPD overlap (ACO): Is there emerging evidence of optimal therapy? -- 18 Potential treatment options for ACO, including biologics: Are there any roles of biologics?. 330 $aThis book elucidates the diagnostic criteria and concept of asthma-COPD overlap (ACO) and provides the latest information on its epidemiology, pathophysiology, diagnostic criteria, and treatment options. It discusses the controversy-causing findings of prognosis of ACO, the novel molecular mechanism including nitrosative stress, radiological or physiological features, findings by research that used HRCT or forced oscillation technique. In addition to a recent animal model of ACO, the role of each biomarker, the latest results of ICS/LAMA/LABA combination inhalers or biologics is also debated. Asthma COPD Overlap -Updated Concept, Pathophysiology, Diagnosis, and Treatment is addressed not only to beginners, but also to physicians engaged in clinical practice, supervisors, and many basic researchers. Covering every aspect of ACO, it serves readers to improve diagnosis or treatment for patients with ACO. 410 0$aRespiratory Disease Series: Diagnostic Tools and Disease Managements,$x2509-5560 606 $aAllergy 606 $aRespiratory organs 606 $aPhysiology 606 $aImmunology 606 $aTherapeutics 606 $aDiagnosis 606 $aAllergology 606 $aRespiratory Physiology 606 $aImmunology 606 $aTherapeutics 606 $aDiagnosis 615 0$aAllergy. 615 0$aRespiratory organs. 615 0$aPhysiology. 615 0$aImmunology. 615 0$aTherapeutics. 615 0$aDiagnosis. 615 14$aAllergology. 615 24$aRespiratory Physiology. 615 24$aImmunology. 615 24$aTherapeutics. 615 24$aDiagnosis. 676 $a616.97 700 $aNagase$b Hiroyuki$01788449 701 $aSugiura$b Hisatoshi$01788450 701 $aShirai$b Toshihiro$01788451 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910980481403321 996 $aAsthma-COPD Overlap$94323391 997 $aUNINA