LEADER 04347nam 22005895 450 001 9910978382503321 005 20250209115235.0 010 $a9783031698002 010 $a3031698002 024 7 $a10.1007/978-3-031-69800-2 035 $a(MiAaPQ)EBC31900416 035 $a(Au-PeEL)EBL31900416 035 $a(CKB)37498920200041 035 $a(DE-He213)978-3-031-69800-2 035 $a(OCoLC)1499722522 035 $a(EXLCZ)9937498920200041 100 $a20250209d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aDrug Interactions in Gastroenterology $eA Clinical Guide /$fedited by Marko Bani?, Damir Erceg 205 $a1st ed. 2024. 210 1$aCham :$cSpringer Nature Switzerland :$cImprint: Humana,$d2024. 215 $a1 online resource (964 pages) 225 1 $aClinical Gastroenterology,$x2197-7704 311 08$a9783031697999 311 08$a3031697995 327 $aLegal Aspects of Drug Use -- Discovery and Preclinical Research -- Clinical Research and Regulatory Review -- Drug Development and Drug Interactions -- Antisecretory Drugs -- Motility Drugs -- Mucosal Protective Agents -- Antibiotics -- Antiinflammatory Drugs -- Adverse Drug Reactions and Drug Interactions -- Types of Drug Interactions -- Enzymes and Transporters Involved in Drug Interactions -- Pharmacogenomics -- Drug-Herbal Interactions -- Drug-Food Ineractions -- How to Avoid Drug Interactions -- Influence of Age on Drug Interactions -- Functional State of Digestive System and Oral Drug Absorption Infections -- Cardiorespiratory Disorders -- Renal Insufficiency -- Hepatal Insufficiency -- Irritable Bowel Syndrome -- Metabolic Disorders -- Immune Mediated Disorders -- CNS Disorders -- Acid Related Disorders -- Intestinal Inflammation -- Liver Disorders -- Pancreato-biliary Disorders -- Motility Disorders. 330 $aThe risk of clinically significant drug interaction rises when a patient increases his intake of medication. While drug interaction can be a prominent cause of illness, in many cases, it can be avoided with proper knowledge and care. This text provides a concise yet comprehensive review of common drug interactions in gastroenterology. The book begins with a preliminary overview of GI drugs, focusing on legal aspects of drug use, clinical research and regulatory review, and drug development. The next section goes over the basic pharmacology of GI drugs, specifically profiling antisecretory drugs, motility drugs, mucosal protective agents, antibiotics, and anti-inflammatory drugs. The third section of the text reviews important aspects of drug interaction; topics covered in this section include the different types of drug interactions, adverse drug reactions and interactions, enzymes and transporters involved in drug interactions, pharmacogenomics, drug-herbal interactions, drug-food interactions, and ways to avoid drug interactions altogether. The book moves on to examine comorbidity and digestive diseases that can result from drug interactions, with particular emphasis on infections, cardiorespiratory disorders, renal insufficiency, IBS, metabolic disorders, and CNS disorders. This section also discusses the influence of age on drug interactions. The final section spotlights comedication that can be used to mitigate disorders caused by drug interactions, specifically reviewing comedication used to treat acid-related disorders, intestinal inflammation, liver disorders, pancreato-biliary disorders, and motility disorders. The text also includes over 100 high-yield illustrations, photographs, and tables. 410 0$aClinical Gastroenterology,$x2197-7704 606 $aInternal medicine 606 $aPsychiatry 606 $aInternal Medicine 606 $aPsychiatry 606 $aInternal Medicine 615 0$aInternal medicine. 615 0$aPsychiatry. 615 14$aInternal Medicine. 615 24$aPsychiatry. 615 24$aInternal Medicine. 676 $a615.7045 700 $aBani?$b Marko$01788565 701 $aErceg$b Damir$01788566 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910978382503321 996 $aDrug Interactions in Gastroenterology$94323592 997 $aUNINA