LEADER 04495nam 2200685 a 450 001 9910451469003321 005 20200520144314.0 010 $a1-282-19374-0 010 $a9786612193743 010 $a3-11-019716-2 024 7 $a10.1515/9783110197167 035 $a(CKB)1000000000520534 035 $a(EBL)325657 035 $a(OCoLC)191935487 035 $a(SSID)ssj0000257547 035 $a(PQKBManifestationID)11240295 035 $a(PQKBTitleCode)TC0000257547 035 $a(PQKBWorkID)10253639 035 $a(PQKB)10765384 035 $a(MiAaPQ)EBC325657 035 $a(DE-B1597)32186 035 $a(OCoLC)979761460 035 $a(DE-B1597)9783110197167 035 $a(Au-PeEL)EBL325657 035 $a(CaPaEBR)ebr10194865 035 $a(CaONFJC)MIL219374 035 $a(EXLCZ)991000000000520534 100 $a20040106d2004 uy 0 101 0 $aeng 135 $aur||#|||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aText types and the history of English$b[electronic resource] /$fby Manfred Go?rlach 205 $aReprint 2013 210 $aBerlin ;$aNew York $cMouton de Gruyter$dc2004 215 $a1 online resource (352 p.) 225 1 $aTrends in linguistics. Studies and monographs ;$v139 300 $aDescription based upon print version of record. 311 $a3-11-017372-7 320 $aIncludes bibliographical references (p. [309]-321) and indexes. 327 $tFront matter --$tContents --$t1. Preface --$t2. A history of text types: A componential analysis --$t3. Text types and the linguistic history of modern English --$t4. Text types and language history: The cooking recipe --$t5. A linguistic history of advertising --$t6. The church hymn --$t7. Lexical entries --$t8. Linguistic aspects of jokes --$t9. Text types and the history of Scots --$t10. Text types and Indian English --$t11. Facsimiles --$tBack matter 330 $aThe history of modern European languages has been largely determined by the range of functions they have acquired, particularly after 1500. This development necessitated a notable expansion of their syntax and lexis, but is most characteristically reflected in the conventionalization of text types. Starting from the German concept of Textsorte as developed from the 1960's onwards, the present account is a first comprehensive attempt at charting the field for the history and present-day situation of the English language. In text types, a designation is linked with a more or less stable form which guides the writer's production as well as the reader's expectation, permitting one to recognize straightforward uses as well as deliberate misuses. Some two thousand of such designations are here listed with minimal definitions and dates for first occurrences. The discussion then concentrates on selected types, which are seen as especially illustrative for English: book dedications, cooking recipes, advertisements, church hymns, lexical entries, and jokes. Their functions and development over time are treated in correlation with their specific linguistic characteristics and adaptations to different period styles and social changes in the readership. The functional range of text types in traditions outside England and the consequences of the export of English categories are exemplified by the history of Scots/Scottish English and of English in India. The arguments are accompanied by a lavish supply of textual excerpts and more than fifty pages of facsimiles, which are especially relevant for insights derived from typographical features. A full bibliography and indices are provided at the end. The book will prove useful for decisions on the constitution of representative text corpora and stimulate research into a greater number of individual text types as well as contrastive analyses at least among European languages. 410 0$aTrends in linguistics.$pStudies and monographs ;$v139. 606 $aEnglish language$xHistory 606 $aEnglish language$xVariation 606 $aLiterary form$xHistory 608 $aElectronic books. 615 0$aEnglish language$xHistory. 615 0$aEnglish language$xVariation. 615 0$aLiterary form$xHistory. 676 $a420/.9 700 $aGo?rlach$b Manfred$0403284 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910451469003321 996 $aText types and the history of english$9543739 997 $aUNINA LEADER 04849nam 2200661 450 001 9910808374903321 005 20200520144314.0 010 $a1-118-89256-9 010 $a1-118-89255-0 010 $a1-118-89257-7 035 $a(CKB)3710000000374806 035 $a(EBL)1964101 035 $a(SSID)ssj0001456758 035 $a(PQKBManifestationID)12620708 035 $a(PQKBTitleCode)TC0001456758 035 $a(PQKBWorkID)11435409 035 $a(PQKB)11158382 035 $a(PQKBManifestationID)16036445 035 $a(PQKB)24869438 035 $a(MiAaPQ)EBC1964101 035 $a(DLC) 2015014108 035 $a(Au-PeEL)EBL1964101 035 $a(CaPaEBR)ebr11032414 035 $a(CaONFJC)MIL770051 035 $a(OCoLC)904959309 035 $a(PPN)200131869 035 $a(EXLCZ)993710000000374806 100 $a20150331h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAntineoplastic drugs $eorganic synthesis /$fDaniel Lednicer 210 1$aChichester, England :$cWiley,$d2015. 210 4$dİ2015 215 $a1 online resource (230 p.) 300 $aDescription based upon print version of record. 311 $a1-118-89254-2 320 $aIncludes bibliographical references at the end of each chapters and indexes. 327 $aTitle Page; Copyright Page; Contents; Preface; Introduction; Chapter 1 Alkylating Agents; 1.1 bis-Chloroethyl Amines; 1.2 Several Other Chloroethyl Agents; 1.3 Platinum-Based Antineoplastic Agents; 1.4 Miscellaneous Alkylating Agents; References; Chapter 2 Antimetabolites; 2.1 Introduction; 2.2 Folate Antagonists; 2.2.1 Compounds with Glutamate Side Chain; 2.2.2 Compounds Lacking the Glutamate Moiety; 2.2.3 Methoxylated Benzenes; 2.3 Pyrimidines and Purines; 2.3.1 Aglycones; 2.3.2 Saccharide-Linked Compounds; References; Chapter 3 Hormone Blocking Anticancer Drugs; 3.1 Introduction 327 $a3.2 Estrogen Antagonists3.2.1 Estrogen Antagonists; 3.2.2 Aromatase Inhibitors; 3.3 Androgen Antagonists; 3.3.1 Non-steroidal Antian drogens; 3.3.2 Steroid Androgen Antagonists; References; Chapter 4 Topoisomerase Inhibitors; 4.1 Introduction; 4.2 Anthracyclines; 4.3 Anthraquinones and Anthrapyrazoles; 4.3.1 Anthraquinones with Two Aminoalkyl Side Chains; 4.3.2 Anthraquinones with a Fused Pyrazole Ring; 4.3.3 Heterocyclic Anthraquinones; 4.4 Camptothecins; 4.4.1 Compounds from Modified Camptothecin; 4.4.2 Camptothecins by Total Synthesis; 4.5 Miscellaneous Topoisomerase Inhibitors; References 327 $aChapter 5 Mitotic Inhibitors5.1 Introduction; 5.2 Taxanes; 5.3 Wholly Synthetic Compounds; 5.3.1 Carbocyclic Compounds; 5.3.2 Peptide-Like Inhibitors; 5.3.3 Monocyclic Heterocyclic Inhibitors; 5.3.4 Bicyclic 5:6 Heterocyclic Inhibitors; 5.3.5 Bicyclic 6:6 Heterocyclic Tubulin Inhibitors; References; Chapter 6 Matrix Metalloproteinase Inhibitors; 6.1 Introduction; 6.2 Hydroxamates; 6.2.1 Agents with an Isobutyl Moiety; 6.2.2 A Thiomorpholine; 6.2.3 Sulfamates; 6.2.4 Miscellaneous Compounds; References; Chapter 7 Histone Deacetylase Inhibitors; 7.1 Introduction; 7.2 Hydroxamates 327 $a7.3 PhenylenediaminesReferences; Chapter 8 Enzyme Inhibitor, Part I, Tyrosine Kinases; 8.1 Introduction; 8.2 Epidermal Growth Factor Inhibitors; 8.3 VEGF; 8.3.1 Fused Ring Compounds; 8.3.2 Linear Arrays; 8.4 SRC Nonreceptor Tyrosine Kinase; 8.5 PDGF; 8.6 EGF; 8.7 Other TKI; 8.7.1 Linear Arrays; 8.7.2 Compounds with Two Fused Rings; 8.8 Janus Kinase Inhibitors; References; Chapter 9 Enzyme Inhibitors: Part II Additional Targets; 9.1 Serine-Threonine Kinase Inhibitors; 9.2 Additional Enzyme Inhibitors; 9.2.1 Farnesyl Transferase Inhibitors; 9.2.2 Cyclin-Dependent Kinase Inhibitors 327 $a9.2.3 Proteasome Inhibitors9.2.4 PARP Inhibitors; 9.2.5 Various Other Enzyme Inhibitors; References; Chapter 10 Miscellaneous Antineoplastic Agents; 10.1 Acyclic; 10.2 Monocyclic; 10.3 Two Linked Rings; 10.4 Rings on a Chain; 10.4.1 Two Rings; 10.4.2 Four and More Rings; 10.5 Fused Rings; 10.5.1 Indoles; 10.5.2 Purine-Like; 10.5.3 Tetralins and a Naphthalene; 10.5.4 Etc.; References; Appendix A; Index of Heterocycle Syntheses; Subject Index; EULA 330 $a"Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations"--$cProvided by publisher. 606 $aAntineoplastic agents 615 0$aAntineoplastic agents. 676 $a616.994061 686 $aSCI007000$2bisacsh 700 $aLednicer$b Daniel$091622 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910808374903321 996 $aAntineoplastic drugs$93960821 997 $aUNINA LEADER 03773nam 2200733Ia 450 001 9910975403103321 005 20200520144314.0 010 $a9786612932892 010 $a9781282932890 010 $a1282932896 010 $a9780226721873 010 $a0226721876 024 7 $a10.7208/9780226721873 035 $a(CKB)2670000000059465 035 $a(EBL)625219 035 $a(OCoLC)692204526 035 $a(SSID)ssj0000467789 035 $a(PQKBManifestationID)12169074 035 $a(PQKBTitleCode)TC0000467789 035 $a(PQKBWorkID)10496793 035 $a(PQKB)10518629 035 $a(StDuBDS)EDZ0000121923 035 $a(DE-B1597)523100 035 $a(OCoLC)747946399 035 $a(DE-B1597)9780226721873 035 $a(Au-PeEL)EBL625219 035 $a(CaPaEBR)ebr10433756 035 $a(CaONFJC)MIL293289 035 $a(MiAaPQ)EBC625219 035 $a(Perlego)1851040 035 $a(EXLCZ)992670000000059465 100 $a20050811d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe coldest crucible $eArctic exploration and American culture /$fMichael F. Robinson 205 $a1st ed. 210 $aChicago $cUniversity of Chicago Press$d2006 215 $a1 online resource (219 p.) 300 $aDescription based upon print version of record. 311 08$a9780226721842 311 08$a0226721841 320 $aIncludes bibliographical references (p. 181-197) and index. 327 $tFrontmatter -- $tContents -- $tIllustrations -- $tAcknowledgments -- $tIntroduction -- $t1. Building an Arctic Tradition -- $t2. A Man of Science and Humanity -- $t3. An Arctic Divided -- $t4. Dying Like Men -- $t5. The New Machines -- $t6. Savage Campaigns -- $tConclusion -- $tNotes -- $tBibliography -- $tIndex 330 $aIn the late 1800s, "Arctic Fever" swept across the nation as dozens of American expeditions sailed north to the Arctic to find a sea route to Asia and, ultimately, to stand at the North Pole. Few of these missions were successful, and many men lost their lives en route. Yet failure did little to dampen the enthusiasm of new explorers or the crowds at home that cheered them on. Arctic exploration, Michael F. Robinson argues, was an activity that unfolded in America as much as it did in the wintry hinterland. Paying particular attention to the perils facing explorers at home, The Coldest Crucible examines their struggles to build support for the expeditions before departure, defend their claims upon their return, and cast themselves as men worthy of the nation's full attention. In so doing, this book paints a new portrait of polar voyagers, one that removes them from the icy backdrop of the Arctic and sets them within the tempests of American cultural life. With chronological chapters featuring emblematic Arctic explorers-including Elisha Kent Kane, Charles Hall, and Robert Peary-The Coldest Crucible reveals why the North Pole, a region so geographically removed from Americans, became an iconic destination for discovery. 606 $aExplorers$zUnited States$xHistory$y19th century 606 $aScientists$zUnited States$xHistory$y19th century 606 $aScience$zUnited States$xHistory$y19th century 607 $aArctic regions$xDiscovery and exploration$xAmerican 615 0$aExplorers$xHistory 615 0$aScientists$xHistory 615 0$aScience$xHistory 676 $a910/.9163/2 686 $aRY 30026$2rvk 700 $aRobinson$b Michael F$g(Michael Frederick),$f1966-$037662 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910975403103321 996 $aThe coldest crucible$94364723 997 $aUNINA