LEADER 05344nam 22004815 450 001 9910838279503321 005 20240422234818.0 010 $a9789819976911 010 $a981997691X 024 7 $a10.1007/978-981-99-7691-1 035 $a(MiAaPQ)EBC31172457 035 $a(Au-PeEL)EBL31172457 035 $a(DE-He213)978-981-99-7691-1 035 $a(CKB)30481253900041 035 $a(OCoLC)1423106645 035 $a(EXLCZ)9930481253900041 100 $a20240220d2024 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGlycoimmunology in Xenotransplantation /$fby Cheorl-Ho Kim 205 $a1st ed. 2024. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024. 215 $a1 online resource (378 pages) 311 08$a9789819976904 311 08$a9819976901 327 $aPreface -- Table of Contents -- Keywords -- Chapter 1 Origin of Life and Diversity of Glycan -- Chapter 2 Current State of Xenotransplantation -- Chapter 3 Pig as Best Source for Clinical Xenotransplantation -- Chapter 4 Glycan Antigens of Pig Interfering with Xenotransplantation: Three Immune Responses from the Glycans -- Chapter 5 Glycosylation in Eukaryotes -- Chapter 6 Human Red Blood Cell (RBC) Blood Groups System -- Chapter 7 Non-ABO Blood Group Systems -- Chapter 8 Conceptual Aspect of Xenotransplantation from ABO Blood Type-incompatible Organ Allotransplantation -- Chapter 9 Classification of Rejection in Host Recipients in Xenotransplantation -- Chapter 10 Hyper Acute Rejection (HAR) -- Chapter 11 Non-?1,3Gal Carbohydrate Antigenic Epitopes -- Chapter 12. Other non-a1,3Gal Antigens -- Chapter 13 Blood Mediated Inflammatory Reaction (IBMIR) and Prevention of IBMIR -- Chapter 14 Protection of Cellular Antigens from Xenoreactive Responses as Overcoming Strategies -- Chapter 15 Delayed Rejection of Xenograft (DRX) -- Chapter 16 Blood Coagulation as Coagulation Dysregulation -- Chapter 17 Xenogeneic and Allogenic Cellular Rejection (CR) -- Chapter 18 Induction of Xenograft Tolerance and Chimerism as an Alternative Prevention of Xenograft Rejection -- Chapter 19 Genome Editing and Transgenes in Pigs -- Chapter 20 Solid Xenoorgan Xenotransplantation -- Chapter 21 Infectious Risk and Protection -- Chapter 22 Concept of Chimeric Organisms such as Human-non-human chimera (HNH-chimera) -- Chapter 23 Intra-bone Bone Marrow Transplantation -- Chapter 24 The Future of Pig Organ and Cell Xenotransplantation -- Chapter 25 Conclusions. 330 $aThis book describes general glycobiology in emphasizing the structures, biosynthesis, glycosylation and distribution of the glycans and xenogenic glycoantigens in eukaryotic cells of mammals including mouse, swine, chimpanzee and human. In the middle, I have focused on topics in xenotransplantation glycobiology and expand descriptions of allogenic and xenoantigenic transplantation to open the dawn in insights into the origin of life. One of the biological diversity, named species diversity, is a phenomenon environmentally adapted from the evolutionary process for long period. The distinct structures of glycans discriminate each organism and are the essential molecular basis of the discrimination and difference between the organisms, giving an incompatibility between the different species. Diversity and variations in carbohydrate chain structures between family, species, kingdoms and domains mark the global pattern and signs of immune self- and non-self recognition. In human, diversityin ABH blood group antigens is observed in human family and this type pattern distinguishes individuals from a pan-family to non-dividable unit of the family. Blood transfusion and organ transplantation are impossible even in the allogenic cross between humans if carbohydrates are ignored. This explains how and how human beings are a lonely existence. ABH-related antibodies induce hemolysis or hyperacute or allograft rejection due to incompatible graft property even between the same species. The incompatibility is an immunologic rejection when the recipient host receives the tissues or organs from the different species of donors, as well-known in pig-to-human xenotransplantation. The immunologic incompatibility between the donor pigs and the recipient human are based on the evolutionary distance between pigs and humans. This distance allows a xenograft rejection between the 2 mammals. Modification or deletion of the specific gene locus for immune rejection on genome of donor animals disrupts the immunological recognition ligands of the donor organs, consequently preventing the immune rejection of the human recipient and xenograft rejection. This book helps undergraduate and graduate students, researcher and professors who are involved in the glycobiology and xenoantigenic biology with recent advances in the xenotransplantation basic and clinic. 606 $aBiology 606 $aBiological Sciences 615 0$aBiology. 615 14$aBiological Sciences. 676 $a617.954 700 $aKim$b Cheorl-Ho$01062709 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910838279503321 996 $aGlycoimmunology in Xenotransplantation$94132048 997 $aUNINA LEADER 03299nam 2200745Ia 450 001 9910975209303321 005 20240313031554.0 010 $a979-82-16-34787-3 010 $a9786613911995 010 $a1-283-59954-6 010 $a0-7391-6999-8 035 $a(CKB)2670000000241768 035 $a(EBL)1021910 035 $a(OCoLC)855502137 035 $a(SSID)ssj0000751658 035 $a(PQKBManifestationID)12308404 035 $a(PQKBTitleCode)TC0000751658 035 $a(PQKBWorkID)10752626 035 $a(PQKB)10350019 035 $a(SSID)ssj0000745325 035 $a(PQKBManifestationID)12367705 035 $a(PQKBTitleCode)TC0000745325 035 $a(PQKBWorkID)10852744 035 $a(PQKB)10757715 035 $a(Au-PeEL)EBL1021910 035 $a(CaPaEBR)ebr10602255 035 $a(CaONFJC)MIL391199 035 $a(OCoLC)835886267 035 $a(MiAaPQ)EBC1021910 035 $a(EXLCZ)992670000000241768 100 $a20100416d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aInternet policy in China $ea field study of internet cafe?s /$fHelen Sun 205 $a1st ed. 210 $aLanham, Md. $cLexington Books$dc2010 215 $a1 online resource (334 p.) 225 0$aLexington studies in political communication 300 $aDescription based upon print version of record. 311 08$a0-7391-1922-2 311 08$a0-7391-1921-4 320 $aIncludes bibliographical references (p. 297-304) and index. 327 $aCover; Title Page; Copyright Page; Dedication Page; Table of Contents; Figures and Tables; Abbreviations and Acronyms; A Note to the Reader; Acknowledgments; Introduction; Part I: Issues at The Macro Level; Chapter One: Techno-Socio Relationships; Chapter Two: The Evolution of Statism in China; Chapter Three: Media Development and Communication Policy; Chapter Four: The State's Response to Internet Technology; Part II: Issues at The Micro Level; Chapter Five: The Public Sphere and the Regulability of Cyberspace; Chapter Six: Internet Cafes and Their Environment 327 $aChapter Seven: Net Bar Visitors and Their Reaction to RegulationChapter Eight: Net Bar Owners and Their Interaction with the State; Conclusion; A Note on Method; Bibliography; Index; About the Author 330 $a Internet Policy in China: A Field Study of Internet Cafe?s reports the results of a multi-layered study of the Internet cafe? phenomenon in the People's Republic of China. Helen Sun investigates how the Internet has been used by the state and individuals, as well as the implications of Chinese Internet policies and regulations. 410 0$aLexington Studies in Political Communication 606 $aCybercafes$zChina$vCase studies 606 $aInternet$xGovernment policy$zChina 606 $aInternet$xSocial aspects$zChina 615 0$aCybercafes 615 0$aInternet$xGovernment policy 615 0$aInternet$xSocial aspects 676 $a025.0420951 676 $a384.330951 700 $aSun$b Helen$01855138 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910975209303321 996 $aInternet policy in China$94453109 997 $aUNINA