LEADER 02895oam 2200469K 450 001 9910793554503321 005 20230817192709.0 010 $a1-351-62097-5 010 $a1-351-62096-7 010 $a1-315-11208-6 035 $a(CKB)4100000008045358 035 $a(MiAaPQ)EBC5755752 035 $a(OCoLC)1098280014 035 $a(OCoLC-P)1098280014 035 $a(FlBoTFG)9781315112084 035 $a(EXLCZ)994100000008045358 100 $a20190425d2019 uy 0 101 0 $aeng 135 $aurcnu---unuuu 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aTextbook of clinical trials in oncology $ea statistical perspective /$fedited by Susan Halabi, Stefan Michiels 210 1$aBoca Raton, Florida :$cCRC Press,$d[2019] 215 $a1 online resource (645 pages) 300 $a"A Chapman & Hall Book"--Title page. 311 $a1-138-08377-1 320 $aIncludes bibliographical references and index. 330 $aThere is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for statisticians and investigators with minimal clinical trial experience who are interested in pursuing a career in this area. The advancement in genetic and molecular technologies have revolutionized drug development. In recent years, clinical trials have become increasingly sophisticated as they incorporate genomic studies, and efficient designs (such as basket and umbrella trials) have permeated the field. This book offers the requisite background and expert guidance for the innovative statistical design and analysis of clinical trials in oncology. Key Features: Cutting-edge topics with appropriate technical background Built around case studies which give the work a "hands-on" approach Real examples of flaws in previously reported clinical trials and how to avoid them Access to statistical code on the book's website Chapters written by internationally recognized statisticians from academia and pharmaceutical companies Carefully edited to ensure consistency in style, level, and approach Topics covered include innovating phase I and II designs, trials in immune-oncology and rare diseases, among many others 606 $aCancer$xResearch$xStatistical methods 606 $aClinical trials$xStatistical methods 615 0$aCancer$xResearch$xStatistical methods. 615 0$aClinical trials$xStatistical methods. 676 $a616.99400727 702 $aHalabi$b Susan 702 $aMichiels$b Stefan 801 0$bOCoLC-P 801 1$bOCoLC-P 906 $aBOOK 912 $a9910793554503321 996 $aTextbook of clinical trials in oncology$93834417 997 $aUNINA LEADER 04145nam 2200769Ia 450 001 9910974366903321 005 20251117082851.0 010 $a0-429-91666-3 010 $a0-429-90243-3 010 $a0-429-47766-X 010 $a1-283-07049-9 010 $a9786613070494 010 $a1-84940-632-4 035 $a(CKB)2550000000033090 035 $a(EBL)690171 035 $a(OCoLC)723944598 035 $a(SSID)ssj0000524543 035 $a(PQKBManifestationID)11360359 035 $a(PQKBTitleCode)TC0000524543 035 $a(PQKBWorkID)10546452 035 $a(PQKB)10533567 035 $a(MiAaPQ)EBC690171 035 $a(Au-PeEL)EBL690171 035 $a(CaPaEBR)ebr10463934 035 $a(CaONFJC)MIL307049 035 $a(OCoLC)727951066 035 $a(FlBoTFG)9780429477669 035 $a(OCoLC)228374294 035 $a(FINmELB)ELB148047 035 $a(EXLCZ)992550000000033090 100 $a20080517d2008 uy 0 101 0 $aeng 135 $aur||| ||||| 181 $ctxt 182 $cc 183 $acr 200 00$aObject relations and social relations $ethe implications of the relational turn in psychoanalysis /$fedited by Simon Clarke, Herbert Hahn, and Paul Hoggett 205 $aFirst edition. 210 $aLondon $cKarnac$d2008 215 $a1 online resource (304 p.) 225 1 $aEXPL 300 $aDescription based upon print version of record. 311 08$a0-367-10594-2 311 08$a1-85575-563-7 320 $aIncludes bibliographical references and index. 327 $aCover; Copy Right; ABOUT THE EDITORS AND CONTRIBUTORS; INTRODUCTION; CHAPTER ONE: Relational thinking: from culture to couch and couch to culture; CHAPTER TWO: Democratizing psychoanalysis; CHAPTER THREE: Staying close to the subject; CHAPTER FOUR: Relational thinking and welfare practice; CHAPTER FIVE: Artistic output as intersubjective third; CHAPTER SIX: Psycho-social research: relating self, identity, and otherness; CHAPTER SEVEN: The importance of relational thinking in the practice of psycho-social research: ontology, epistemology, methodology, and ethics 327 $aCHAPTER EIGHT: How does a turn towards relational thinking influence consulting practice in organizations and groups?CHAPTER NINE: Inquiry as relational practice: thinking relationally about the practice of teaching and learning 330 3 $aThis book has two essential aims. First, to introduce some of the key assumptions behind relational psychoanalysis to an international audience and to outline the points where this approach counters, complements, or extends existing object relations (Kleinian and Independent) traditions. Second, to consider some of the implications of the relational turn for the application of psychoanalytic concepts and methods beyond the consulting room. The emergence of what has become known as "the relational turn" in psychoanalysis has interesting implications not just for clinical practice, but for other psychoanalytically informed practices, such as group relations, the human service professions, and social research. Relational forms of psychoanalysis have emerged primarily in the USA, and as a result their core concepts and methods are less well-known in other countries, including the UK. Moreover, even within the USA, few attempts have so far been made to consider the wider implications of this development for social and political theory; intervention in groups and organizations, and the practice of social research. 410 0$aEXPL 606 $aObject relations (Psychoanalysis) 606 $aInterpersonal relations 606 $aPsychoanalysis 615 0$aObject relations (Psychoanalysis) 615 0$aInterpersonal relations. 615 0$aPsychoanalysis. 676 $a150.195 676 $a150.1957 701 $aClarke$b Simon$f1962-$01879035 701 $aHahn$b Herb$01811910 701 $aHoggett$b Paul$0236425 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910974366903321 996 $aObject relations and social relations$94497699 997 $aUNINA