LEADER 06310nam 2200637Ia 450 001 9910974207503321 005 20251116221035.0 010 $a1-61761-914-0 035 $a(CKB)2560000000067903 035 $a(EBL)3017772 035 $a(SSID)ssj0000417830 035 $a(PQKBManifestationID)12110638 035 $a(PQKBTitleCode)TC0000417830 035 $a(PQKBWorkID)10380210 035 $a(PQKB)10866897 035 $a(MiAaPQ)EBC3017772 035 $a(Au-PeEL)EBL3017772 035 $a(CaPaEBR)ebr10654743 035 $a(OCoLC)923653658 035 $a(BIP)26942014 035 $a(EXLCZ)992560000000067903 100 $a20090414d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aFlavonoids $ebiosynthesis, biological effects and dietary sources /$fRaymond B. Keller, editor 205 $a1st ed. 210 $aNew York $cNova Science Publishers$dc2009 215 $a1 online resource (363 p.) 225 0$aNutrition and diet research progress series 300 $aDescription based upon print version of record. 311 08$a1-60741-622-0 320 $aIncludes bibliographical references and index. 327 $a""FLAVONOIDS: BIOSYNTHESIS, BIOLOGICAL EFFECTS AND DIETARY SOURCES ""; ""FLAVONOIDS: BIOSYNTHESIS, BIOLOGICAL EFFECTS AND DIETARY SOURCES""; ""CONTENTS""; ""PREFACE ""; ""BIOAVAILABILITY AND METABOLISM OF DIETARY FLAVONOIDS a??? MUCH KNOWN a??? MUCH MORE TO DISCOVER ""; ""ABSTRACT""; ""INTRODUCTION ""; ""FLAVONOID ABSORPTION AND METABOLISM IN THE GASTROINTESTINAL TRACT ""; ""The Oral Cavity ""; ""The Stomach ""; ""The Small Intestine ""; ""The Colon and Microflora""; ""DISTRIBUTION OF FLAVONOID METABOLITES ROUND THE BODY ""; ""FLAVONOID BIOAVAILABILITY TO THE CENTRAL NERVOUS SYSTEM "" 327 $a""BIOLOGICAL ACTIVITY OF FLAVONOID METABOLITES """"Quercetin/Flavonols ""; ""Isoflavones ""; ""Catechins ""; ""Other Flavonoids""; ""CONCLUSION ""; ""REFERENCES ""; ""CYTOPROTECTIVE ACTIVITY OF FLAVONOIDS IN RELATION TO THEIR CHEMICAL STRUCTURES AND PHYSICOCHEMICAL PROPERTIES ""; ""ABSTRACT ""; ""INTRODUCTION""; ""CHEMICAL STRUCTURE OF FLAVONOIDS ""; ""PHYSICOCHEMICAL PROPERTIES OF FLAVONOIDS ""; ""The UV Absorption of Flavonoids ""; ""Physical Properties of Flavonoids ""; ""Bond Dissociation Energy (BDE)""; ""Lipophilicity (Log P) ""; ""HEALTH EFFECTS OF FLAVONOIDS "" 327 $a""CYTOPROTECTION ASSAY """"MATERIALS AND METHODS ""; ""Materials ""; ""Assessment of Cell Viability ""; ""Culture and Treatment of HT-29 Cells ""; ""Annexin V Staining and Flow Cytometric Analysis ""; ""Calculation of Results""; ""Cell Death Index (CDI)""; ""Quantum Chemical Calculations ""; ""Calculation of Heat of Formation ""; ""Calculation of Log P ""; ""RESULTS AND DISCUSSION""; ""Cytotoxic Effects of H2O2 ""; ""Cytotoxicity of Flavonoids ""; ""The Influence of Trolox on Cytotoxic Effects of H2O2 ""; ""Structural Related Cytoprotective Activity of Flavonoids "" 327 $a""Effects of Hydroxyl Groups in the B Ring """"Effect of the 3-OH Group, 2,3-Double Bond and 4-Keto Group ""; ""Effect of the Carbohydrate Moieties""; ""Cytoprotective Activities and Physicochemical Properties of Flavonoids ""; ""Correlation between O-H Bond Dissociation Enthalpy (BDE) and Cytoprotective Activity (EC50) of Flavonoids ""; ""Correlation between Partition Coefficient (Log P) and Cytoprotective Activity (EC50) of Flavonoids ""; ""Quantitative Structure-Activity Relationship (QSAR) Model ""; ""CONCLUSION""; ""ACKNOWLEDGMENTS ""; ""REFERENCES "" 327 $a"" OLIGOMERIC NATURE, COLLOIDAL STATE, RHEOLOGY, ANTIOXIDANT CAPACITY AND ANTIVIRAL ACTIVITY OF POLYFLAVONOIDS""""ABSTRACT""; ""INTRODUCTION""; ""THE OLIGOMERIC NATURE OF POLYFLAVONOIDS ""; "" Profisetinindin and Prorobinetinidin Type Polyflavonoids ""; ""Procyanidin and Prodelphinidin Type Polyflavonoids ""; ""Colloidal State of Polyflavonoid Extracts""; ""RHEOLOGY OF INDUSTRIAL POLYFLAVONOIDS ""; ""ANTI-OXYDANT CAPABILITY OF POLYFLAVONOIDS ""; ""ANTIVIRAL ACTIVITY OF POLYFLAVONOIDS ""; ""REFERENCES""; ""GRAPEFRUIT FLAVONOIDS: NARINGIN AND NARINGININ ""; ""ABSTRACT ""; ""INTRODUCTION "" 327 $a""REFERENCES "" 330 $aFlavonoids, also referred to as bioflavonoids, are polyphenol antioxidants found naturally in plants. They are secondary metabolites, meaning they are organic compounds that have no direct involvement with the growth or development of plants. Flavonoids are plant nutrients that when consumed in the form of fruits and vegetables are non-toxic as well as potentially beneficial to the human body. Flavonoids are widely disbursed throughout plants and are what give the flowers and fruits of many plants their vibrant colours. They also play a role in protecting the plants from microbe and insect attacks. More importantly, the consumption of foods containing flavonoids has been linked to numerous health benefits. Though research shows flavonoids alone provide minimal antioxidant benefit due to slow absorption by the body, there is indication that they biologically trigger the production of natural enzymes that fight disease. Recent research indicates that flavonoids can be nutritionally helpful by triggering enzymes that reduce the risk of certain cancers, heart disease, and age-related degenerative diseases. Some research also indicates flavonoids may help prevent tooth decay and reduce the occurrence of common ailments such as the flu. These potential health benefits, many of which have been proven, have become of particular interest to consumers and food manufacturers. Foods that contain high amounts of flavonoids include blueberries, red beans, cranberries, and blackberries. Many other foods, including red and yellow fruits and vegetables and some nuts, also contain flavonoids. Red wine and certain teas also are rich in flavonoids. 410 0$aNutrition and Diet Research Progress 606 $aFlavonoids 606 $aPlant pigments 615 0$aFlavonoids. 615 0$aPlant pigments. 676 $a612/.0154 701 $aKeller$b Raymond B$01864930 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910974207503321 996 $aFlavonoids$94471909 997 $aUNINA