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100   $a20091203d2009      uy         0
101 0 $aeng
135   $aurcn|||||||||
181   $ctxt
182   $cc
183   $acr
200 00$aSystems for research and evaluation for translating genome-based discoveries for health $eworkshop summary /$fTheresa Wizemann, rapporteur ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
205   $a1st ed.
210   $aWashington, D.C. $cNational Academies Press$dc2009
215   $a1 online resource (103 p.)
300   $aDescription based upon print version of record.
311 08$a0-309-13983-X 
320   $aIncludes bibliographical references.
327   $a""Front Matter""; ""Reviewers""; ""Acknowledgments""; ""Contents""; ""1 Introduction""; ""2 Generating Evidence for Decision Making""; ""3 Creating Evidence Systems""; ""4 Current Practices in Moving from Evidence to Decision""; ""5 Panel: Where Are the Gaps?""; ""6 Closing Remarks""; ""References""; ""Appendix A: Workshop Agenda""; ""Appendix B: Speaker Biosketches""
330   $aWith the advent of genome-wide association studies, numerous associations between specific gene loci and complex diseases have been identified-for breast cancer, coronary artery disease, and asthma, for example. This rapidly advancing field of genomics has stirred great interest in "personalized" health care from both the public and private sectors. The hope is that using genomic information in clinical care will lead to reduced health care costs and improved health outcomes as therapies are tailored to the genetic susceptibilities of patients.  A variety of genetically based health care innovations have already reached the marketplace, but information about the clinical use of these treatments and diagnostics is limited. Currently data do not provide information about how a genomic test impacts clinical care and patient health outcomes-other approaches are needed to garner such information.  This volume summarizes a workshop to address central questions related to the development of systems to evaluate clinical use of health care innovations that stem from genome-based research: What are the practical realities of creating such systems? What different models could be used? What are the strengths and weaknesses of each model? How effectively can such systems address questions about health outcomes?
606   $aGenomics$vCongresses
606   $aGenomics$xData processing$vCongresses
606   $aGenomics$xResearch$vCongresses
615  0$aGenomics
615  0$aGenomics$xData processing
615  0$aGenomics$xResearch
676   $a572.8
701   $aWizemann$b Theresa M$0890630
712 02$aInstitute of Medicine (U.S.).$bRoundtable on Translating Genomic-Based Research for Health.
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910974163403321
996   $aSystems for research and evaluation for translating genome-based discoveries for health$94447661
997   $aUNINA