LEADER 00739nam0-2200289 --450 001 9910744996203321 005 20231011171112.0 010 $a88-18-01041-7 100 $a20231011d1988----kmuy0itay5050 ba 101 $aita 102 $aIT 105 $a 001yy 200 1 $a<>sufismo$fSeyyed Hossein Nasr 210 $aMilano$cRusconi$d1988 215 $a195 p.$d22 cm 225 1 $aProblemi attuali 300 $aTrad. di Donatella Venturi 610 0 $aSufismo 676 $a297.4$v21 700 1$aNasr,$bSeyyed Hossein$0202682 801 0$aIT$bUNINA$gREICAT$2UNIMARC 901 $aBK 912 $a9910744996203321 952 $aDFT G20 HONS 01$fFLFBC 959 $aFLFBC 996 $aSufismo$93568887 997 $aUNINA LEADER 06314nam 22007094a 450 001 9910973813403321 005 20251017110112.0 010 $a9786610185344 010 $a9780309171717 010 $a0309171717 010 $a9781280185342 010 $a1280185341 010 $a9780309569705 010 $a0309569702 035 $a(CKB)110986584753150 035 $a(EBL)3377375 035 $a(SSID)ssj0000284928 035 $a(PQKBManifestationID)11912606 035 $a(PQKBTitleCode)TC0000284928 035 $a(PQKBWorkID)10261691 035 $a(PQKB)10380620 035 $a(MiAaPQ)EBC3377375 035 $a(Au-PeEL)EBL3377375 035 $a(CaPaEBR)ebr10071402 035 $a(CaONFJC)MIL18534 035 $a(OCoLC)923270163 035 $a(Perlego)4733837 035 $a(DNLM)970968 035 $a(BIP)6812457 035 $a(EXLCZ)99110986584753150 100 $a20000829d2000 ua 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aToxicological effects of methylmercury /$fCommittee on the Toxicological Effects of Methylmercury, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council 205 $a1st ed. 210 $aWashington, DC $cNational Academy Press$dc2000 215 $a1 online resource (368 p.) 300 $aDescription based upon print version of record. 311 08$a9780309071406 311 08$a0309071402 320 $aIncludes bibliographical references. 327 $a""Toxicological Effects of Methylmercury""; ""Copyright""; ""PREFACE""; ""Contents""; ""EXECUTIVE SUMMARY""; ""THE CHARGE TO THE COMMITTEE""; ""THE COMMITTEE'S APPROACH TO ITS CHARGE""; ""THE COMMITTEE'S EVALUATION""; ""Health Effects of Methylmercury""; ""Determination of the Critical Study for the RfD""; ""Estimation of Dose and Biological Variability""; ""Modeling the Dose-Response Relationships""; ""Public Health Implications""; ""RESEARCH NEEDS""; ""RECOMMENDATIONS""; ""1 INTRODUCTION""; ""SOURCES OF HG""; ""FATE AND TRANSPORT""; ""HEALTH EFFECTS""; ""EXPOSURE EVENTS AND STUDIES"" 327 $a""SUMMARY OF RISK ASSESSMENTS FOR MEHG""""SCIENTIFIC CONTROVERSIES AND SOURCES OF UNCERTAINTY""; ""ORGANIZATION OF THE REPORT""; ""REFERENCES""; ""2 CHEMISTRY, EXPOSURE, TOXICOKINETICS, AND TOXICODYNAMICS ""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""METHODS OF CHEMICAL ANALYSIS""; ""EXPOSURES TO MEHG IN THE U.S. POPULATION""; ""TOXICOKINETICS""; ""Absorption and Distribution""; ""Methylmercury""; ""Dimethylmercury""; ""Elemental Mercury""; ""Inorganic Mercury""; ""Biotransformation""; ""Excretion""; ""MOBILIZATION OF BODY HG""; ""CHEMICAL FORMS OF HG IN TOXICITY"" 327 $a""TOXIC EFFECTS AND TARGET ORGANS""""BIOCHEMICAL MECHANISMS OF TOXICITY""; ""SUMMARY AND CONCLUSIONS""; ""RECOMMENDATIONS""; ""REFERENCES""; ""3 BIOLOGICAL VARIABILITY ""; ""AGE-RELATED SUSCEPTIBILITY""; ""GENDER DIFFERENCES""; ""GENETICS""; ""MECHANISMS OF NUTRITIONAL INFLUENCE ON MEHG HEALTH EFFECTS""; ""Dietary Interactions and Confounding""; ""Selenium""; ""Garlic""; ""Omega-3 Fatty Acids""; ""Protein""; ""Alcohol""; ""Other Foods That Might Influence Hg Uptake""; ""Vitamin E""; ""Nutrient Enhancement of Toxicity""; ""Beneficial Effects of Fish Consumption""; ""TOXICOKINETIC VARIABILITY"" 327 $a""CONCLUSIONS""""RECOMMENDATIONS""; ""REFERENCES""; ""4 DOSE ESTIMATION ""; ""DIETARY ASSESSMENT""; ""BIOMARKERS OF EXPOSURE""; ""Methylmercury in Blood""; ""Methylmercury in Hair""; ""Comparison of Biomarkers of Exposure""; ""ANALYTICAL ERROR IN BIOMARKER MEASUREMENTS""; ""EXPOSURE AND DOSE ASSESSMENT IN THE SEYCHELLES, FAROE ISLANDS, AND NEW ZEALAND STUDIES""; ""SUMMARY AND CONCLUSIONS""; ""RECOMMENDATIONS""; ""REFERENCES""; ""5 HEALTH EFFECTS OF METHYLMERCURY ""; ""CARCINOGENICITY""; ""Human Studies""; ""Animal Studies""; ""GENOTOXICITY""; ""Human Studies""; ""Animal Studies"" 327 $a""In Vitro Studies""""IMMUNOTOXICITY""; ""Human Studies""; ""Animal Studies""; ""Effects on the Adult Immune System""; ""Effects on the Developing Immune System""; ""In Vitro Studies""; ""Autoimmune Response""; ""Human Studies""; ""Animal Studies""; ""REPRODUCTIVE EFFECTS""; ""Human Studies""; ""Animal Studies""; ""RENAL TOXICITY""; ""Human Studies""; ""Animal Studies""; ""CARDIOVASCULAR EFFECTS""; ""Human Studies""; ""Animal Studies""; ""HEMATOLOGICAL EFFECTS""; ""DEVELOPING CENTRAL-NERVOUS-SYSTEM TOXICITY""; ""Human Studies""; ""High-Dose Poisonings""; ""Poisoning Episode in Japan"" 327 $a""Poisoning Episode in Iraq"" 330 $aMercury is widespread in our environment. Methylmercury, one organic form of mercury, can accumulate up the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Combustion processes, especially coal-fired power plants, are major sources of mercury contamination in the environment. The U.S. Environmental Protection Agency (EPA) is considering regulating mercury emissions from those plants. Toxicological Effects of Methylmercury reviews the health effects of methylmercury and discusses the estimation of mercury exposure from measured biomarkers, how differences between individuals affect mercury toxicity, and appropriate statistical methods for analysis of the data and thoroughly compares the epidemiological studies available on methylmercury. Included are discussions of current mercury levels on public health and a delineation of the scientific aspects and policy decisions involved in the regulation of mercury. This report is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report also provides an excellent example of the implications of decisions in the risk assessment process for a larger audience. 606 $aMethylmercury$xToxicology 615 0$aMethylmercury$xToxicology. 676 $a615.9/25663 712 02$aNational Research Council (U.S.).$bCommittee on the Toxicological Effects of Methylmercury. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910973813403321 996 $aToxicological effects of methylmercury$94361573 997 $aUNINA