LEADER 04799nam 2200373 450 001 9910598170203321 005 20230325100709.0 035 $a(CKB)4100000002152764 035 $a(NjHacI)994100000002152764 035 $a(EXLCZ)994100000002152764 100 $a20230325d2018 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aHybrid Modelling and Multi- Parametric Control of Bioprocesses /$fedited by Christoph Herwig 210 1$aBasel :$cMDPI - Multidisciplinary Digital Publishing Institute,$d2018. 210 4$d©2018 215 $a1 online resource (148 pages) $cillustrations 311 $a3-03842-745-4 320 $aIncludes bibliographical references. 327 $aAbout the Special Issue Editor -- Preface to "Hybrid Modelling and Multi-Parametric Control of Bioprocesses" -- Karen Schwab, Jennifer Lauber and Friedemann Hesse Fluorometric In Situ Monitoring of an Escherichia coli Cell Factory with Cytosolic Expression of Human Glycosyltransferase GalNAcT2: Prospects and Limitations -- Karen Schwab and Friedemann Hesse Estimating Extrinsic Dyes for Fluorometric Online Monitoring of Antibody Aggregation in CHO Fed-Batch Cultivations -- Maike Kuschel, Flora Siebler and Ralf Takors Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in LargeScale Bioreactors -- Dominik Egger, Ivo Schwedhelm, Jan Hansmann and Cornelia Kasper Hypoxic Three-Dimensional Scaffold-Free Aggregate Cultivation of Mesenchymal Stem Cells in a Stirred Tank Reactor -- Dominik Egger, Monica Fischer, Andreas Clementi, Volker Ribitsch, Jan Hansmann and Cornelia Kasper Development and Characterization of a Parallelizable Perfusion Bioreactor for 3D Cell Culture -- Dennis Vier, Stefan Wambach, Volker Schnemann and Klaus-Uwe Gollmer Multivariate Curve Resolution and Carbon Balance Constraint to Unravel FTIR Spectra fromFed-Batch Fermentation Samples -- Julian Kopp, Christoph Slouka, Sophia Ulonska, Julian Kager, Jens Fricke, Oliver Spadiut and Christoph Herwig Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3) -- Rimvydas Simutis and Andreas L ¨ubbert Hybrid Approach to State Estimation for Bioprocess Control -- Thomas Zahel, Lukas Marschall, Sandra Abad, Elena Vasilieva, Daniel Maurer, Eric M. Mueller, Patrick Murphy, Thomas Natschlger, Ccile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Workflow for Criticality Assessment Applied in Biopharmaceutical Process Validation Stage 1 -- Thomas Zahel, Stefan Hauer, Eric M. Mueller, Patrick Murphy, Sandra Abad, Elena Vasilieva, Daniel Maurer, C´ecile Brocard, Daniela Reinisch, Patrick Sagmeister and Christoph Herwig Integrated Process Modeling-A Process Validation Life Cycle Companion. 330 $aThe goal of bioprocessing is to optimize process variables, such as product quantity and quality, in a reproducible, scalable, and transferable manner. However, bioprocesses are highly complex. A large number of process parameters and raw material attributes exist, which are highly interactive, and may vary from batch to batch. Those interactions need to be understood, and the source of variance must be identified and controlled. While purely data-driven correlations, such as chemometric models of spectroscopic data, may be employed for the understanding how process parameters are related to process variables, they can hardly be deployed outside of the calibration space. Currently, mechanistic models, models based on mechanistic links and first principles, are in the focus of development. They are perceived to allow transferability and scalability, because mechanistics can be extrapolated. Moreover, the models deliver a large range of hardly-measureable states and physiological parameters. The current Special Issue wants to display current solutions and case studies of development and deployment of hybrid models and multi-parametric control of bioprocesses. It includes: -Models for Bioprocess Monitoring -Model for Bioreactor Design and Scale Up -Hybrid model solutions, combinations of data driven and mechanistic models. -Model to unravel mechanistic physiological regulations -Implementation of hybrid models in the real-time context -Data science driven model for process validation and product life cycle management. 606 $aBiotechnological process control 615 0$aBiotechnological process control. 676 $a660.6 702 $aHerwig$b Christoph 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910598170203321 996 $aHybrid Modelling and Multi- Parametric Control of Bioprocesses$92948857 997 $aUNINA LEADER 03789oam 2200565I 450 001 9910973155203321 005 20190826145055.0 010 $a9789004307094 010 $a9004307095 024 7 $a10.1163/9789004307094 035 $a(CKB)3710000000647732 035 $a(EBL)4514049 035 $a(SSID)ssj0001662686 035 $a(PQKBManifestationID)16447374 035 $a(PQKBTitleCode)TC0001662686 035 $a(PQKBWorkID)14826265 035 $a(PQKB)11268793 035 $a(MiAaPQ)EBC4514049 035 $a(nllekb)BRILL9789004307094 035 $a(EXLCZ)993710000000647732 100 $a20151002d2016 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aApproaches to complex predicates /$fedited by Le?a Nash ; Pollet Samvelian 210 1$aLeiden ;$aBoston :$cBrill,$d[2016] 215 $a1 online resource (301 p.) 225 0 $aSyntax & Semantics ;$v41 300 $aIncludes index. 311 08$a9789004306981 311 08$a9004306986 320 $aIncludes bibliographical references and index. 327 $tFront Matter /$rLéa Nash and Pollet Samvelian -- $tIntroduction: Approaches to Complex Predicates /$rLéa Nash and Pollet Samvelian -- $tFrom Adpositions to Events: The Case of Location Verbs in Basque /$rAne Berro -- $tUniverbation of Light Verb Compounds and the Obligatory Coding Principle /$rDenis Creissels -- $tVariation and Grammaticalisation in Bantu Complex Verbal Constructions: The Dynamics of Information Growth in Swahili, Rangi and SiSwati /$rHannah Gibson and Lutz Marten -- $tTuning in to the Verb-Particle Construction in English /$rAdele E. Goldberg -- $tNoun-Verb Complex Predicates in Hindi and the Rise of Non-Canonical Subjects /$rAnnie Montaut -- $tMalayalam Ceyy-Support and Its Relation to Event and Argument Structure /$rPooja Paul -- $tComplex Predicates as Complementation Structures /$rPeter Svenonius -- $tComplex Predicate Formation via Voice Incorporation /$rSusanne Wurmbrand -- $tIndex /$rLéa Nash and Pollet Samvelian. 330 $aComplex predicates can be loosely defined as a sequence of items that behave as a single predicate, projecting a single argument structure within a clause. Each of the members of the predicate contributes part of the information ordinarily associated with a single head. The present volume presents a collection of theoretical linguistic results on the study of complex predicates in different perspectives and with a variety of approaches. Important empirical and theoretical issues cutting across various subfields of linguistics are being addressed in this book, such as : ? Syntactic and semantic modeling of complex predicate formation: compositionality, argument structure, event structure. ? Differences between syntactic and morphological processes of lexeme formation. ? Typological and diachronic issues in complex predicate formation. ? Neo-Davidsonian analyses of abstract predicate decomposition and its morphological correlates Contributors are: Ane Berro, Denis Creissels, Hannah Gibson, Adele Goldberg, Lutz Marten, Annie Montaut, Léa Nash, Pooja Paul, Pollet Samvelian, Peter Svenonius, and Susanne Wurmbrand. 410 0$aSyntax and Semantics$v41. 606 $aGrammar, Comparative and general$xVerb phrase 606 $aGrammar, Comparative and general$xSyntax 615 0$aGrammar, Comparative and general$xVerb phrase. 615 0$aGrammar, Comparative and general$xSyntax. 676 $a415/.6 701 $aNash$b Le?a$01787354 701 $aSamvelian$b Pollet$01787355 801 0$bNL-LeKB 801 1$bNL-LeKB 906 $aBOOK 912 $a9910973155203321 996 $aApproaches to complex predicates$94320745 997 $aUNINA