LEADER 05959nam 2200721 a 450 001 9910973132003321 005 20251017110214.0 010 $a9786612948558 010 $a9780309185349 010 $a0309185343 010 $a9781282948556 010 $a1282948555 010 $a9780309156127 010 $a0309156122 035 $a(CKB)2560000000070083 035 $a(SSID)ssj0000466958 035 $a(PQKBManifestationID)11293086 035 $a(PQKBTitleCode)TC0000466958 035 $a(PQKBWorkID)10490106 035 $a(PQKB)10746876 035 $a(MiAaPQ)EBC3378721 035 $a(Au-PeEL)EBL3378721 035 $a(CaPaEBR)ebr10439406 035 $a(CaONFJC)MIL294855 035 $a(OCoLC)703274056 035 $a(Perlego)4739391 035 $a(DNLM)1554855 035 $a(EXLCZ)992560000000070083 100 $a20110114d2010 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAntibiotic resistance $eimplications for global health and novel intervention strategies : workshop summary /$fEileen R. Choffnes, David A. Relman, and Alison Mack, rapporteurs ; Institute of Medicine of the National Academies 205 $a1st ed. 210 $aWashington, D.C. $cNational Academies Press$d2010 215 $axxii, 473 p. $cill. (some col.) 300 $a"Forum on Microbial Threats, Board on Global Health." 311 08$a9780309156110 311 08$a0309156114 320 $aIncludes bibliographical references. 327 $gWorkshop overview.$gOrganization of the workshop summary ;$gAntimicrobial drug resistance in context ;$gMicrobial evolution and the origins of resistance ;$gAnthropogenic influences on AMR ;$gStaying ahead of AMR ;$gWorkshop overview references --$gAppendix A: Contributed manuscripts.$tThe case for pathogen-specific therapy /$rArturo Casadevall ;$tWaves of resistance : Staphylococcus aureus in the antibiotic era /$rHenry F. Chambers and Frank R. DeLeo ;$tSublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis /$rMichael A. Kohanski, Mark A. DePristo, and James J. Collins ;$tAntibiotic-induced resistance flow /$rPatrice Courvalin ;$tActinobacteria : the good, the bad, and the ugly /$rVivan Miao and Julian Davies ;$tAntibiotics for emerging pathogens /$rMichael A. Fischbach and Christopher T. Walsh ;$tAverting a potential post-antibiotic era /$rShelley Hearne ;$tAntibiotic effectiveness : new challenges in natural resource management /$rMarkus Herrmann and Ramanan Laxminarayan ;$tThe role of health care facilities /$rRamanan Laxminarayan ;$tResponding to the global antibiotic resistance crisis : the APUA chapter network /$rStuart B. Levy ;$tChallenges and opportunities in antibiotic discovery /$rKim Lewis ;$tPopulation mobility, globalization, and antimicrobial resistance /$rDouglas W. MacPherson ... [et al.] ;$tThe bacterial challenge : a time to react, executive summary /$rEuropean Centre for Disease Prevention and Control and European Medicines Agency Joint Working Group--Dominique L. Monnet ;$tThe effects of antibiotic and pesticide resistance on public health /$rDavid Pimentel ;$tClinical issues and outcomes associated with rising antimicrobial resistance /$rLouis B. Rice ;$tWorld Health Organization activities for control of antimicrobial resistance due to use of antimicrobials in animals intended for food /$rJørgen Schlundt and Awa Aidara-Kane ;$tThe antibacterial pipeline : why is it drying up, and what must be done about it? /$rBrad Spellberg ;$tChallenges in antimicrobial susceptibility testing of clinical and environmental isolates /$rFred C. Tenover ;$tMeasuring the cost of antimicrobial-resistant infections : the feasibility and accuracy of economic analysis using electronic medical record databases /$rRebecca R. Roberts ... [et al.] ;$tThe antibiotic resistome /$rGerard D. Wright --$gAppendix B: Agenda --$gAppendix C: Acronyms --$gAppendix D: Glossary --$gAppendix E: Forum member biographies --$gAppendix F: Speaker biographies. 330 $aFor decades it seemed as if modern medicine had conquered many of the infectious diseases that once threatened human and animal health. But years of using, misusing, and overusing antibiotics and other antimicrobial drugs have led to the emergence of multidrug-resistant "superbugs." Some strains of bacteria and viruses are now resistant to all but a single drug, while others have no effective treatments at all. The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant bacteria and viruses and their implications for global health. Speakers explored the evolutionary, genetic, and ecological origins of antimicrobial drug resistance and its effects on human and animal health worldwide. Participants discussed the causes of drug resistance; strategies for extending the life of antimicrobial drugs; alternative approaches for treating infections; incentives and disincentives for prudent antimicrobial drug use; and prospects for the next generation of antimicrobial treatments. This document summarizes the workshop--$cSource other than Library of Congress. 606 $aDrug resistance in microorganisms$xResearch$vCongresses 606 $aAntibiotics$vCongresses 606 $aPublic health$vCongresses 615 0$aDrug resistance in microorganisms$xResearch 615 0$aAntibiotics 615 0$aPublic health 676 $a615.7/922 701 $aChoffnes$b Eileen R$01086319 701 $aRelman$b David A$01806597 701 $aMack$b Alison$01085987 712 02$aInstitute of Medicine (U.S.).$bForum on Microbial Threats. 712 02$aInstitute of Medicine (U.S.).$bBoard on Global Health. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910973132003321 996 $aAntibiotic resistance$94360842 997 $aUNINA