LEADER 02601nam0 2200517 i 450 001 VAN00124962 005 20240806100817.733 017 70$2N$a9783319938912 100 $a20191029d2018 |0itac50 ba 101 $aeng 102 $aCH 105 $a|||| ||||| 200 1 $aRecent Advances in Computational Engineering$eProceedings of the 4th International Conference on Computational Engineering (ICCE 2017) in Darmstadt$fMichael Schäfer ... [et al.] editors 210 $aCham$cSpringer$d2018 215 $ax, 199 p.$cill.$d24 cm 410 1$1001VAN00027129$12001 $aLecture notes in computational science and engineering$1210 $aBerlin [etc.]$cSpringer$d1997-$v124 500 1$3VAN00236465$aRecent Advances in Computational Engineering$91563735 606 $a49-XX$xCalculus of variations and optimal control; optimization [MSC 2020]$3VANC019757$2MF 606 $a60-XX$xProbability theory and stochastic processes [MSC 2020]$3VANC020428$2MF 606 $a65-XX$xNumerical analysis [MSC 2020]$3VANC019772$2MF 606 $a68-XX$xComputer science [MSC 2020]$3VANC019670$2MF 606 $a70-XX$xMechanics of particles and systems [MSC 2020]$3VANC021390$2MF 606 $a74-XX$xMechanics of deformable solids [MSC 2020]$3VANC022466$2MF 606 $a76-XX$xFluid mechanics [MSC 2020]$3VANC019858$2MF 606 $a80-XX$xClassical thermodynamics, heat transfer [MSC 2020]$3VANC022357$2MF 610 $aComputational engineering$9KW:K 610 $aEngineering Applications$9KW:K 610 $aMultiphase Flows$9KW:K 610 $aMultiphysics Simulation$9KW:K 610 $aNumerics$9KW:K 610 $aOptimization$9KW:K 610 $aParallel algorithms$9KW:K 610 $aPartial Differential Equations$9KW:K 610 $aSolver Methods$9KW:K 620 $aCH$dCham$3VANL001889 702 1$aSchafer$bMichael$3VANV087870 712 12$aInternational Conference on Computational Engineering$d4.$f2017$eDarmstadt, Germany$3VANV096387 712 $aSpringer $3VANV108073$4650 801 $aIT$bSOL$c20250926$gRICA 856 4 $uhttp://doi.org/10.1007/978-3-319-93891-2$zE-book ? Accesso al full-text attraverso riconoscimento IP di Ateneo, proxy e/o Shibboleth 899 $aBIBLIOTECA DEL DIPARTIMENTO DI MATEMATICA E FISICA$1IT-CE0120$2VAN08 912 $fN 912 $aVAN00124962 950 $aBIBLIOTECA DEL DIPARTIMENTO DI MATEMATICA E FISICA$d08DLOAD e-book 1341 $e08eMF1341 20191029 996 $aRecent Advances in Computational Engineering$91563735 997 $aUNICAMPANIA LEADER 03438nam 2200589 a 450 001 9910973020903321 005 20251117080248.0 010 $a1-61470-207-1 035 $a(CKB)2670000000149002 035 $a(EBL)3019817 035 $a(SSID)ssj0000691226 035 $a(PQKBManifestationID)12225615 035 $a(PQKBTitleCode)TC0000691226 035 $a(PQKBWorkID)10629372 035 $a(PQKB)11478296 035 $a(MiAaPQ)EBC3019817 035 $a(Au-PeEL)EBL3019817 035 $a(CaPaEBR)ebr10671382 035 $a(OCoLC)777549337 035 $a(BIP)25870615 035 $a(EXLCZ)992670000000149002 100 $a20090625d2009 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMannose-binding lectin in the innate immune system /$fIara de Messias-Reason and Angelica B.W. Boldt 205 $a1st ed. 210 $aHauppauge, N.Y. $cNova Biomedical Books$d2009 215 $a1 online resource (99 p.) 300 $aDescription based upon print version of record. 311 08$a1-60692-716-7 320 $aIncludes bibliographical references and index. 327 $aIntro -- MANNOSE-BINDING LECTIN INTHE INNATE IMMUNE SYSTEM -- MANNOSE-BINDING LECTIN INTHE INNATE IMMUNE SYSTEM -- CONTENTS -- PREFACE -- INTRODUCTION -- 1. MANNOSE BINDING LECTIN (MBL)CHARACTERISTICS -- 1a. MBL2 Gene and Protein Structure -- 1b. MBL2 Transcription and Translation -- 2. MBL FUNCTIONS -- 2a. Activation of Complement -- 2b. Opsonophagocytosis -- 2c. Modulation of Inflamation -- 2d. Recognition of Altered Self and Apoptosis -- 2e. Other MBL Functions -- 3. MBL2 GENE POLYMORPHISM -- 3a. MBL2 Variants and Allelic Haplotypes -- 3b. Worldwide Distribution of MBL2 Haplotypes -- MBL2 ASSOCIATION WITH DISEASES -- 1. POSITIVE ASSOCIATION OF MBL DEFICIENCYWITH DISEASES -- 1a. Otitis Media and other Pediatric Infections -- 1b. Meningitis -- 1c. Mycoplasma Infection -- 1d. Emergent Viral Infection -- 1e. Fungal Infections -- 1f. Malaria -- 1g. Neutropenia -- 1h. Hepatitis B -- 1i. HIV Infection -- 1j. Cystic Fibrosis -- 1k. Systemic Inflammatory Response Syndrome -- 1l. Cardiovascular Diseases -- 1m. Systemic Lupus Erythematosus -- 1n. Gastrointestinal Diseases -- 2. NEGATIVE ASSOCIATION OF MBL DEFICIENCYWITH DISEASES -- 2a. Leprosy -- 2b. Tuberculosis -- 2c. Leishmaniasis -- 2d. Hepatitis C -- 2e. Rheumatic Heart Disease -- 2f. Rheumatoid Arthritis -- 2g. Ischemia/Reperfusion Injury -- 2h. Other Diseases -- 3. MBL AND HETEROZYGOTE ADVANTAGE -- 4. MBL THERAPY -- CONCLUSION -- REFERENCES -- INDEX. 330 $aMannose-binding lectin (MBL) is a plasma protein with a role in the innate immune system. This text summarises the understanding of human MBL biology and introduces the general aspects of the structure, function and genetics of MBL, as well as an analysis of the role of MBL in the predisposition to clinically relevant diseases. 606 $aLectins 606 $aNatural immunity 606 $aMannose 615 0$aLectins. 615 0$aNatural immunity. 615 0$aMannose. 676 $a616.079 700 $aDe Messias-Reason$b Iara$01861833 701 $aBoldt$b Angelica B. W$01861834 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910973020903321 996 $aMannose-binding lectin in the innate immune system$94468046 997 $aUNINA