LEADER 03078nam 2200625 a 450 001 9910972624403321 005 20251017110056.0 010 $a0-309-22067-X 010 $a1-280-12334-6 010 $a9786613527202 010 $a0-309-22065-3 035 $a(CKB)2670000000176340 035 $a(OCoLC)794491570 035 $a(CaPaEBR)ebrary10554791 035 $a(SSID)ssj0000645747 035 $a(PQKBManifestationID)11380818 035 $a(PQKBTitleCode)TC0000645747 035 $a(PQKBWorkID)10683766 035 $a(PQKB)10169540 035 $a(MiAaPQ)EBC3378946 035 $a(Au-PeEL)EBL3378946 035 $a(CaPaEBR)ebr10554791 035 $a(CaONFJC)MIL352720 035 $a(OCoLC)785373830 035 $a(DNLM)1583262 035 $a(EXLCZ)992670000000176340 100 $a20120509d2012 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aFacilitating collaborations to develop combination investigational cancer therapies $eworkshop summary /$fMargie Patlak, Erin Balogh, and Sharyl J. Nass, rapporteurs ; Institute of Medicine of the National Academies 205 $a1st ed. 210 $aWashington, D.C. $cNational Academies Press$d2012 215 $a1 online resource (117 p.) 300 $a"National Cancer Policy Forum, Board on Health Care Services." 311 08$a0-309-22064-5 320 $aIncludes bibliographical references. 327 $aIntroduction -- Why Combinations and Collaborations Are Necessary -- Scientific Challenges in Developing Investigational Combination Therapies -- Overcoming Cultural Challenges to Collaborations Legal Issues in Collaborations -- Financial Challenges -- Regulatory Issues -- Codevelopment of Therapies for HIV as a Model -- Examples of Collaborations Relevant to Cancer -- Wrapping Up -- Appendix A: Examples of Collaborations -- Appendix B: Workshop Agenda -- References -- Acronyms. 330 $a"Advances in biomedical research have increased our understanding of the complex nature of disease and the interaction of multiple molecular pathways involved in cancer. Combining investigational products early in their development is thought to be a promising strategy for identifying effective therapies. The IOM's National Cancer Policy Forum held a workshop to discuss challenges and identify potential solutions to improve collaboration and advance the development of combination investigational cancer therapies."--Publisher's description. 606 $aCancer$xTreatment 615 0$aCancer$xTreatment. 701 $aPatlak$b Margie$01607028 701 $aBalogh$b Erin$01089066 701 $aNass$b Sharyl J$0857626 712 02$aNational Cancer Policy Forum (U.S.) 712 02$aInstitute of Medicine (U.S.).$bBoard on Health Care Services. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910972624403321 996 $aFacilitating collaborations to develop combination investigational cancer therapies$94446112 997 $aUNINA