LEADER 03262nam 22007214a 450 001 9910972079303321 005 20251116215721.0 010 $a9786611730475 010 $a9781281730473 010 $a1281730475 010 $a9780300129700 010 $a030012970X 024 7 $a10.12987/9780300129700 035 $a(CKB)1000000000472014 035 $a(StDuBDS)AH23049610 035 $a(SSID)ssj0000233951 035 $a(PQKBManifestationID)11202524 035 $a(PQKBTitleCode)TC0000233951 035 $a(PQKBWorkID)10235606 035 $a(PQKB)10705938 035 $a(MiAaPQ)EBC3419998 035 $a(DE-B1597)484980 035 $a(OCoLC)952732441 035 $a(DE-B1597)9780300129700 035 $a(Au-PeEL)EBL3419998 035 $a(CaPaEBR)ebr10170024 035 $a(OCoLC)923589448 035 $a(Perlego)1089361 035 $z(OCoLC)952732441 035 $a(EXLCZ)991000000000472014 100 $a20051114d2006 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aReconceiving the gene $eSeymour Benzer's adventures in phage genetics /$fFrederic Lawrence Holmes ; edited by William C. Summers 205 $a1st ed. 210 $aNew Haven $cYale University Press$dc2006 215 $a1 online resource (352 p.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a9780300110784 311 08$a0300110782 320 $aIncludes bibliographical references (p. [303]-329) and index. 327 $aClassical mendelian genetics -- Genetics and the phage biologists -- The physicist becomes a phage biologist -- To Paris and back -- Teaching and research at Purdue -- Entering the rII region -- Crossing into the fine structure -- Is gene a dirty word? -- The survival of the "gene". 330 $aThis book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer's accomplishments are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age. Drawing on Benzer's remarkably complete record of his experiments, his correspondence, and published sources, this book reconstructs how the former physicist initiated his work in phage biology and achieved his landmark investigation. The account of Benzer's creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise. 606 $aGeneticists$zUnited States$vBiography 606 $aBacteriophages$xGenetics 606 $aViral genetics$xHistory 615 0$aGeneticists 615 0$aBacteriophages$xGenetics. 615 0$aViral genetics$xHistory. 676 $a576.5092 676 $aB 700 $aHolmes$b Frederic Lawrence$0726772 701 $aSummers$b William C$01809769 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910972079303321 996 $aReconceiving the gene$94360720 997 $aUNINA