LEADER 04768nam 2200793Ia 450 001 9910971290503321 005 20251116220544.0 010 $a9786611093570 010 $a9780309179621 010 $a0309179629 010 $a9781281093578 010 $a1281093572 010 $a9780309111683 010 $a0309111684 035 $a(CKB)1000000000479986 035 $a(EBL)3378301 035 $a(SSID)ssj0000169497 035 $a(PQKBManifestationID)11924666 035 $a(PQKBTitleCode)TC0000169497 035 $a(PQKBWorkID)10203383 035 $a(PQKB)11469700 035 $a(MiAaPQ)EBC3378301 035 $a(Au-PeEL)EBL3378301 035 $a(CaPaEBR)ebr10197085 035 $a(CaONFJC)MIL109357 035 $a(OCoLC)923277699 035 $a(Perlego)4734452 035 $a(BIP)14594007 035 $a(EXLCZ)991000000000479986 100 $a20070927d2007 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHealth effects of beryllium exposure $ea literature review /$fCommittee on Beryllium Alloy Exposures, Committee on Toxicology, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council of the National Academies 205 $a1st ed. 210 $aWashington, DC $cNational Academies Press$dc2007 215 $a1 online resource (109 p.) 300 $aDescription based upon print version of record. 311 08$a9780309111676 311 08$a0309111676 320 $aIncludes bibliographical references. 327 $a""Front Matter""; ""Preface""; ""Contents""; ""Abbreviations""; ""Summary""; ""1 Introduction""; ""2 Exposure Assessment""; ""3 Sensitization and Chronic Beryllium Disease""; ""4 Genotoxicity and Carcinogenicity""; ""5 Assessment of Other Health End Points""; ""References""; ""Appendix: Biographic Information on the Committee on Beryllium Alloy Exposures"" 330 $aBeryllium is an important metal that is used in a number of industries-including the defense, aerospace, automotive, medical, and electronics industries-because of its exceptional strength, stability, and heat-absorbing capability. It is found in a variety of technologies, including nuclear devices, satellite systems, missile systems, radar systems, bushings and bearings in aircraft and heavy machinery, x-ray machines used for mammography, cellular telephone components, computer components, and connectors for fiber optics. To help determine the steps necessary to protect its workforce from the adverse effects of exposure to beryllium used in military aerospace applications, the U.S. Air Force requested that the National Research Council's Committee on Toxicology (COT) conduct an independent evaluation of the scientific literature on beryllium, provide risk estimates for cancer and noncancer health end points, and make recommendations about specific tests for surveillance and biomonitoring of workers. The request specified that two reports be produced to accomplish those tasks. The first is to provide a review of the scientific literature on beryllium, and the second will expand more critically on the review in considering the maximum chronic inhalation exposure levels that are unlikely to produce adverse health effects, in estimating carcinogenic risks, and in providing guidance on testing methods for surveillance and monitoring of worker populations and other specific issues detailed in the statement of task. In response to the U.S. Air Force request, COT convened the Committee on Beryllium Alloy Exposures, which prepared this first report. Health Effects of Beryllium Exposure: A Literature Review identifies the available toxicologic, epidemiologic, and other literature on beryllium that is most relevant for addressing the statement of task, focusing primarily on beryllium sensitization, CBD, and cancer. 606 $aBeryllium$xToxicology$vBibliography 606 $aBeryllium$xHealth aspects$vBibliography 606 $aRisk assessment 606 $aBeryllium$xtoxicity 606 $aBerylliosis 606 $aOccupational Exposure 606 $aRisk Assessment 608 $aReview. 615 0$aBeryllium$xToxicology 615 0$aBeryllium$xHealth aspects 615 0$aRisk assessment. 615 2$aBeryllium$xtoxicity. 615 2$aBerylliosis. 615 2$aOccupational Exposure. 615 2$aRisk Assessment. 676 $a615.9 712 02$aNational Research Council (U.S.).$bCommittee on Beryllium Alloy Exposures. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910971290503321 996 $aHealth effects of beryllium exposure$94353940 997 $aUNINA