LEADER 04036nam 2200709 a 450 001 9910970520503321 005 20251116232508.0 010 $a0-309-17868-1 010 $a1-281-20935-X 010 $a9786611209353 010 $a0-309-11367-9 035 $a(CKB)1000000000484562 035 $a(EBL)3378867 035 $a(SSID)ssj0000125268 035 $a(PQKBManifestationID)11136730 035 $a(PQKBTitleCode)TC0000125268 035 $a(PQKBWorkID)10026964 035 $a(PQKB)10741170 035 $a(Au-PeEL)EBL3378867 035 $a(CaPaEBR)ebr10495467 035 $a(OCoLC)923284373 035 $a(MiAaPQ)EBC3378867 035 $a(BIP)53858605 035 $a(BIP)14742164 035 $a(EXLCZ)991000000000484562 100 $a20090908d2008 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCombined exposures to hydrogen cyanide and carbon monoxide in army operations $einitial report /$fNational Research Council of the National Academies 205 $a1st ed. 210 $aWashington, D.C. $cNational Academies Press$dc2008 215 $a1 online resource (41 p.) 300 $aDescription based upon print version of record. 311 08$a0-309-11366-0 320 $aIncludes bibliographical references (p. 20-22). 327 $a""Front Matter""; ""Preface""; ""Contents""; ""Summary""; ""1 Introduction""; ""2 Mechanisms of Carbon Monoxide and Hydrogen Cyanide Toxicity""; ""3 A Brief Review of Hydrogen Cyanide and Carbon Monoxide Toxicity""; ""4 Summary of the Effects of Combined Exposure to Carbon Monoxide and Hydrogen Cyanide and Recommendation for Combined-Exposure Risk Assessment""; ""5 Pharmacokinetics and Mathematical Modeling for Assessing Toxicity of Mixtures of Chemicals""; ""6 Appropriateness of Measurement of Blood or Air Levels of Cyanide""; ""7 Conclusions and Recommendations""; ""References"" 327 $a""Appendix: Biographical Information on the Committee on Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations"" 330 $aIn response to a request from the U.S. Army, a committee convened by the National Research Council (NRC) conducted the first in a sequence of studies evaluating the combined health effects of low-level exposure to two chemicals Army personnel are likely to be exposed to in firing tank weapons. The Army sought information on whether the two chemicals, hydrogen cyanide and carbon monoxide, result in similar health impacts and should be assessed together when establishing exposure limits. Based on a review of the scientific literature, the report finds that the biochemical health impacts of the chemicals are similar and that the Army's proposed approach to setting exposure limits is appropriate. Because previous research has focused on high exposures, this initial NRC report recommends that futher neurological studies at low concentrations of exposure to the chemicals be conducted. 606 $aHydrocyanic acid$xToxicology 606 $aCarbon monoxide$xToxicology 606 $aChemical weapons 606 $aHealth risk assessment 615 0$aHydrocyanic acid$xToxicology. 615 0$aCarbon monoxide$xToxicology. 615 0$aChemical weapons. 615 0$aHealth risk assessment. 676 $a358.344 712 02$aNational Research Council (U.S.).$bBoard on Environmental Studies and Technology. 712 02$aNational Research Council (U.S.).$bDivision on Earth and Life Studies. 712 02$aNational Academies Press (U.S.) 712 02$aNational Research Council (U.S.).$bCommittee on Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations. 712 02$aNational Research Council (U.S.).$bCommittee on Technology. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910970520503321 996 $aCombined exposures to hydrogen cyanide and carbon monoxide in army operations$94446251 997 $aUNINA