LEADER 03697oam 2200673I 450 001 9910970277203321 005 20251117101429.0 010 $a0-429-09493-0 010 $a981-4411-60-4 024 7 $a10.1201/b15667 035 $a(CKB)2670000000394376 035 $a(EBL)1408057 035 $a(SSID)ssj0001034605 035 $a(PQKBManifestationID)11620428 035 $a(PQKBTitleCode)TC0001034605 035 $a(PQKBWorkID)11017308 035 $a(PQKB)10797125 035 $a(OCoLC)874179793 035 $a(MiAaPQ)EBC1408057 035 $a(OCoLC)870909189 035 $a(EXLCZ)992670000000394376 100 $a20180331h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aBiofunctional surface engineering /$fedited by Martin Scholz 205 $a1st ed. 210 1$aBoca Raton :$cPan Stanford Publishing,$d[2014] 210 4$dİ2014 215 $a1 online resource (339 p.) 300 $aDescription based upon print version of record. 311 08$a981-4411-61-2 320 $aIncludes bibliographical references at the end of each chapters. 327 $aFront Cover; Dedication; Contents; Preface; Acknowledgment; Chapter 1 - Regulatory Requirements for Medical Devices, Including Combinations with Biological Products or Drugs as an Integral Part; Chapter 2 - Terminal Radiation Sterilization of Combination Products; Chapter 3 - Polyelectrolyte Multilayers as Functional Coatings for Controlled Biomolecular Interactions; Chapter 4 - Polyelectrolyte Multilayers as Functional Coatings for Controlled Biomolecular Interactions; Chapter 5 - Surface Characteristics and Biofilms; Chapter 6 - Antimicrobial Implant Coating 327 $aChapter 7 - Small-Angle X-Ray Spectroscopy as a Method to Monitor the Three-Dimensional Structure of Immobilized Biomolecules on Medical Device Scaffolds during ProductionChapter 8 - Aptamers as Biomimetic Surface Coatings for Blood-Contacting Implants; Chapter 9 - Microneedles and Nanopatches for Transdermal Vaccination; Chapter 10 - Autoantibodies as Biomarkers for Disease Diagnosis; Chapter 11 - Biofunctionalized Wound Dressings for Advanced Wound Care; Chapter 12 - Circulating Tumor Cell: Trapping Devices 327 $aChapter 13 - Evidence Generation for Medical Devices: The Case of Cemented Joint Replacement Surgery in Arthroplasty RegistriesBack Cover 330 $aSuccessful biofunctional surface engineering will determine the future of medical devices such as orthopedic implants, stents, catheters, vaccine scaffolds, wound dressings, and extracorporeal circulation devices. Moreover, the biosensor and diagnostic chip technology will evolve rapidly due to the growing medical need for personalized medicine. A major drawback in these technologies is the need for terminally sterilized products. However, novel and safe technologies, including coupling, stabilization, and protection of effector molecules, enable terminal sterilization without functional lo 606 $aBioengineering 606 $aBiomedical engineering 606 $aBiomedical materials 606 $aBiologicals 606 $aSterilization 606 $aCoatings 615 0$aBioengineering. 615 0$aBiomedical engineering. 615 0$aBiomedical materials. 615 0$aBiologicals. 615 0$aSterilization. 615 0$aCoatings. 676 $a620.00420157419 702 $aScholz$b Martin$f1960- 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910970277203321 996 $aBiofunctional surface engineering$94486747 997 $aUNINA