LEADER 03375nam 2200769Ia 450 001 9910970128803321 005 20251017110057.0 010 $a9786610193196 010 $a9780309176644 010 $a0309176646 010 $a9781280193194 010 $a1280193190 010 $a9780309587792 010 $a0309587794 010 $a9780585143880 010 $a0585143889 035 $a(CKB)110986584751570 035 $a(EBL)3376385 035 $a(SSID)ssj0000111917 035 $a(PQKBManifestationID)11125315 035 $a(PQKBTitleCode)TC0000111917 035 $a(PQKBWorkID)10086234 035 $a(PQKB)10726043 035 $a(MiAaPQ)EBC3376385 035 $a(Au-PeEL)EBL3376385 035 $a(CaPaEBR)ebr10055575 035 $a(CaONFJC)MIL19319 035 $a(OCoLC)923263278 035 $a(Perlego)4735769 035 $a(DNLM)808781 035 $a(BIP)1847313 035 $a(EXLCZ)99110986584751570 100 $a19951020d1995 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBiologic markers in urinary toxicology /$fSubcommittee on Biologic Markers in Urinary Toxicology, Committee on Biologic Markers, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council 205 $a1st ed. 210 $aWashington, D.C. $cNational Academy Press$d1995 215 $a1 online resource (322 p.) 300 $a"B-509."--T.p. verso. 311 08$a9780309052283 311 08$a0309052289 320 $aIncludes bibliographical references (p. 227-309). 327 $aIntroduction -- Toxic exposure of the urinary tract -- Biologic markers of susceptibility and exposure -- Biologic markers of effect -- Biologic markers in extrapolation -- New technologies -- Conclusions and recommendations. 330 $aDiseases of the kidney, bladder, and prostate exact an enormous human and economic toll on the population of the United States. This book examines prevention of these diseases through the development of reliable markers of susceptibility, exposure, and effect and the promise that new technologies in molecular biology and sophisticated understanding of metabolic pathways, along with classical approaches to the study of nephrotoxicants and carcinogens, can be developed and prevention of the diseases achieved. The specific recommendations included in this book complement those made in the previous three volumes on biomarkers, Biologic Markers in Reproductive Toxicology (1989), Biologic Markers in Pulmonary Toxicology (1989), and Biologic Markers in Immunotoxicology (1991). 606 $aNephrotoxicology 606 $aBiochemical markers 606 $aGenitourinary organs$xDiseases$xTreatment 606 $aTumor markers 606 $aXenobiotics$xToxicology 615 0$aNephrotoxicology. 615 0$aBiochemical markers. 615 0$aGenitourinary organs$xDiseases$xTreatment. 615 0$aTumor markers. 615 0$aXenobiotics$xToxicology. 676 $a616.63 712 02$aNational Research Council (U.S.).$bBoard on Environmental Studies and Toxicology. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910970128803321 996 $aBiologic markers in urinary toxicology$94353816 997 $aUNINA