LEADER 03507nam 2200577 a 450 001 9910969164803321 005 20251116181731.0 010 $a1-61470-905-X 035 $a(CKB)2550000001042510 035 $a(EBL)3020298 035 $a(SSID)ssj0000874083 035 $a(PQKBManifestationID)12467055 035 $a(PQKBTitleCode)TC0000874083 035 $a(PQKBWorkID)10878395 035 $a(PQKB)10639367 035 $a(MiAaPQ)EBC3020298 035 $a(Au-PeEL)EBL3020298 035 $a(CaPaEBR)ebr10676515 035 $a(OCoLC)828868938 035 $a(BIP)35284245 035 $a(BIP)35284321 035 $a(EXLCZ)992550000001042510 100 $a20111003d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAcute lymphoblastic leukemia $eetiology, pathogenesis and treatments /$fSevero Vecchione and Luigi Tedesco, editors 205 $a1st ed. 210 $aNew York $cNova Science Publishers, Inc.$dc2012 215 $a1 online resource (251 p.) 225 1 $aCancer etiology diagnosis and treatments 300 $a"Nova biomedical." 311 08$a1-61470-872-X 320 $aIncludes bibliographical references and index. 327 $aGenome wide association studies in pediatric acute lymphoblastic leukemia : pathogenesis and therapy / Kyriaki Hatziagapiou ... [et al.] -- Mice deficient for the Slp65 signaling protein : a model for Pre-B cell acute lymphoblastic leukemia / Van B.T. Ta, Rudi W. Hendriks -- Childhood acute lymphoblastic leukemia / Adriana Za?mecni?kova -- Systems approaches to childhood leukemogenesis / George I. Lambrou -- Histone deacetylase inhibitors : pre-clinical and clinical evidence in treating acute lymphoblastic leukemia / Ana Lucia Abujamra -- A therapeutic target in leukemia : the NK-1 receptor / Miguel Mun?oz, Ana Gonza?lez-Ortega, Rafael Coven?as -- Minimal residual disease monitoring in childhood acute lymphoblastic leukemia / Katerina Katsibardi -- Clinical relevance and application of cytogenetic approaches in pediatric acute lymphoblastic leukaemia / Maria Braoudaki -- Maintenance therapy in Ph negative adult acute lymphoblastic leukemia / Michael Doubek, Jiri? Mayer -- The role of innate and adaptive immunity in childhood acute lymphoblastic leukemia / Maria Hatzistilianou, Agiou Ioannou. 330 $aAcute lymphoblastic leukemia (ALL) is a malignant disorder of the bone marrow in which a lymphoid precursor cell becomes genetically altered resulting in dysregulated proliferation and clonal expansion of neoplastic cells. It is the most common malignancy in children, representing nearly one third of all pediatric cancers. In this book, the authors present topical research in the study of acute lymphoblastic leukemia including genome wide association studies in pediatric acute lymphoblastic leukemia; mice deficient for the Slp65 signaling protein which is a model for ALL; histone deacetylase inhibitors and maintenance therapy in Ph negative adult acute lymphoblastic leukemia. 410 0$aCancer etiology, diagnosis, and treatments. 606 $aLymphoblastic leukemia 615 0$aLymphoblastic leukemia. 676 $a616.99/419071 701 $aVecchione$b Severo$01865620 701 $aTedesco$b Luigi$01865621 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910969164803321 996 $aAcute lymphoblastic leukemia$94472767 997 $aUNINA