LEADER 04062nam 22006253 450 001 9910968952803321 005 20241007163914.0 010 $a9781788010009 010 $a1788010000 010 $a9781788019316 010 $a1788019318 035 $a(MiAaPQ)EBC6816747 035 $a(Au-PeEL)EBL6816747 035 $a(CKB)19948214600041 035 $a(OCoLC)1287135754 035 $a(MiAaPQ)EBC7422958 035 $a(Au-PeEL)EBL7422958 035 $a(EXLCZ)9919948214600041 100 $a20241007d2022 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBionanodesign $eOld Forms for New Functions /$fMaxim Ryadnov 205 $aSecond edition. 210 1$aLondon, England :$cThe Royal Society of Chemistry,$d[2022] 210 4$dİ2022 215 $a1 online resource (214 pages) 225 1 $aISSN Series 311 08$aPrint version: Ryadnov, Maxim Bionanodesign Cambridge : Royal Society of Chemistry,c2021 9781782628163 320 $aIncludes bibliographical references. 327 $aCover -- Bionanodesign: Old Forms for New Functions 2nd Edition -- Preface to the First Edition -- Preface to the Second Edition -- Contents -- Chapter 1 - Introductory Notes -- References -- Chapter 2 - DNA as a Self- programming Module for Nanodesigns -- 2.1 Introduction -- 2.2 Chemistry of DNA -- 2.3 DNA Topology Motifs -- 2.3.1 Primary DNA Motifs -- 2.3.2 Secondary DNA Motifs -- 2.3.3 Secondary Motifs Without Sticky- ended Cohesion -- 2.4 DNA Tiles -- 2.5 Programmed DNA Assembly -- 2.5.1 DNA Origami -- 2.5.2 DNA Nanotubes: Intermediate Scaffolds for 2D and 3D Systems -- 2.5.3 Biofunctional 3D DNA Origami -- 2.6 Outlook -- References -- Chapter 3 - Bioinspired Nanodesigns for Molecular Encapsulation -- 3.1 Introduction -- 3.2 Old Forms of Macromolecular Encapsulation Inspire Nanoscale Designs -- 3.2.1 Triskelion Topology as a Template for Cage- like Assemblies -- 3.2.2 Cage- like Encapsulation for Nanomaterial Synthesis -- 3.2.3 Native Protein Shell and Virus Templates -- 3.3 The Challenge of Gene Therapy: Towards an Artificial Virus -- 3.3.1 Synthetic Polymer Particles for Gene Encapsulation Via Complexation -- 3.3.2 Cationic Peptides Condensing Genes for Intracellular Delivery -- 3.3.3 Lipid, Glyco and Peptide Amphiphiles for Vesicular Nanodesigns -- 3.4 Regular Geometric Forms for Virus- like Designs -- 3.5 Outlook -- References -- Chapter 4 - Nanoscale Designs for Tissue Regeneration -- 4.1 Introduction -- 4.2 The Extracellular Matrix (ECM) - Its Role and Composition -- 4.2.1 Structural ECM Constituents -- 4.2.2 Fibrillogenesis as the Mechanism of Building the ECM -- 4.2.3 ECM Materials from Biological Sources -- 4.3 Mimicking ECM by Design -- 4.3.1 Polymer Mimetics of the ECM -- 4.3.2 Fibrous Mimetics of the ECM -- 4.3.3 Non- collagenous Assembly Mimetics of the ECM -- 4.3.4 Monomorphic Fibre Mimetics versus Matrix Formation. 327 $a4.3.5 Minimalist Fibrous Gelators for an Artificial ECM -- 4.4 Non- matrix Mimetics of the ECM -- 4.5 Outlook -- References -- Chapter 5 - Concluding Remarks -- Subject Index. 330 $aThis new edition highlights contemporary approaches for designing nanostructures that employ naturally derived self-assembling motifs as synthetic platforms. 410 0$aISSO (Series) 606 $aNanobiotechnologie 606 $aNanobiotechnology 606 $aRecombinant molecules 606 $aStructure$xActivity$xRelationship 606 $aStructure-activity relationships (Biochemistry) 615 0$aNanobiotechnologie. 615 0$aNanobiotechnology. 615 0$aRecombinant molecules. 615 0$aStructure$xActivity$xRelationship. 615 0$aStructure-activity relationships (Biochemistry) 676 $a530 700 $aRyadnov$b Maxim$01808483 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910968952803321 996 $aBionanodesign$94358739 997 $aUNINA