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100   $a20080102d2007      uy         0
101 0 $aeng
135   $aurcn|||||||||
181   $ctxt
182   $cc
183   $acr
200 10$aApplications of toxicogenomic technologies to predictive toxicology and risk assessment /$fCommittee on Applications of Toxicogenomic Technologies to Predictive Toxicology ; Board on Environmental Studies and Toxicology ; Board on Life Studies ; Division on Earth and Life Studies ; National Research Council of the National Academies
205   $a1st ed.
210   $aWashington, D.C. $cNational Academies Press$dc2007
215   $a1 online resource (299 p.) 
300   $aBibliographic Level Mode of Issuance: Monograph
311 08$a9780309112987 
311 08$a0309112982 
320   $aIncludes bibliographical references.
327   $aIntroduction -- Toxicogenomic technologies -- Experimental design and data analysis -- Application to exposure assessment -- Application to hazard screening -- Application to analyzing variation in human susceptibility -- Application to the study of mechanisms of action -- Other potential applications of toxicogenomic technologies to risk assessment -- Validation -- Sample and data collection and analysis -- Ethical, legal, and social issues -- Conculsions and recommendations.
330   $aThe new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new ways--an effort requiring funding, interagency coordination, and data management strategies.
606   $aGenetic toxicology
606   $aDNA microarrays$xStatistical methods
606   $aHealth risk assessment
606   $aCarcinogenesis
615  0$aGenetic toxicology.
615  0$aDNA microarrays$xStatistical methods.
615  0$aHealth risk assessment.
615  0$aCarcinogenesis.
676   $a616/.042
712 02$aNational Academies Press (U.S.)
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910967991303321
996   $aApplications of toxicogenomic technologies to predictive toxicology and risk assessment$94368603
997   $aUNINA