LEADER 01199nam 2200373 450 001 9910798684103321 005 20230808194809.0 010 $a1-78635-793-3 035 $a(CKB)3710000000831040 035 $a(MiAaPQ)EBC4649499 035 $a(EXLCZ)993710000000831040 100 $a20160904h20162016 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aEngineering computations $einternational journal for computer-aided engineering and software : ICASI 2015 /$fguest editor Dr Teen-Hang Meen 210 1$a[West Yorkshire, England] :$cEmerald Group Publishing Limited,$d2016. 210 4$d©2016 215 $a1 online resource (253 pages) $cillustrations 225 0 $aEngineering Computations,$x0264-4401 ;$vVolume 33, Number 6 311 $a1-78635-791-7 606 $aComputer-aided design$xStandards 615 0$aComputer-aided design$xStandards. 676 $a620.00420285 702 $aMeen$b Teen-Hang 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910798684103321 996 $aEngineering computations$9794717 997 $aUNINA LEADER 05051nam 2200649 a 450 001 9910965693103321 005 20251017110112.0 010 $a9786610195701 010 $a9781280195709 010 $a1280195703 010 $a9780309573146 010 $a0309573149 010 $a9780585155289 010 $a0585155283 035 $a(CKB)110986584753404 035 $a(SSID)ssj0000106823 035 $a(PQKBManifestationID)11114201 035 $a(PQKBTitleCode)TC0000106823 035 $a(PQKBWorkID)10133232 035 $a(PQKB)10936946 035 $a(MiAaPQ)EBC3376661 035 $a(Au-PeEL)EBL3376661 035 $a(CaPaEBR)ebr10056937 035 $a(OCoLC)923264831 035 $a(Perlego)4734312 035 $a(DNLM)764191 035 $a(BIP)101208 035 $a(EXLCZ)99110986584753404 100 $a19940323d1993 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 13$aAn assessment of the NIH Women's Health Initiative /$fCommittee to Review the NIH Women's Health Initiative, Food and Nutrition Board, and Board on Health Sciences Policy, Institute of Medicine ; Susan Thaul and Dana Hotra, editors 205 $a1st ed. 210 $aWashington, D.C. $cNational Academy Press$d1993 215 $axv, 142 p 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a9780309049894 311 08$a030904989X 320 $aIncludes bibliographical references (p. 91-93). 327 $aAn Assessment of the NIH Women's Health Initiative -- Copyright -- Preface -- Contents -- List of Figures -- Executive Summary -- THE WOMEN'S HEALTH INITIATIVE -- THE IOM STUDY -- FINDINGS AND SUGGESTIONS -- Clinical Trial -- Factorial Design -- Sample Characteristics -- Proposed Analytic Techniques -- Ethics -- Minority Analysis Plan -- Specificity of Intervention and Effect -- Outcome Definition and Measurement -- Recruitment, Retention, and Adherence -- Secular Trends -- Provision of Health Care Services to Participants -- Cost -- Observational Study -- Community Prevention Study -- RECOMMENDATIONS -- Clinical Trial -- Observational Study -- Community Prevention Study -- RESPONSES TO THE STATEMENT OF TASK -- 1 Introduction -- DESCRIPTION OF THE NIH WOMEN'S HEALTH INITIATIVE -- HISTORY OF INSTITUTE OF MEDICINE INVOLVEMENT -- COMMITTEE SELECTION AND PARTICIPATION -- STATEMENT OF TASK -- COMMITTEE ACTIVITIES -- 2 Clinical Trial -- INTRODUCTION -- RATIONALE -- General Issues -- Integration of the CT with Other Components of the WHI -- 3 Observational Study -- RATIONALE -- DESIGN AND METHODS -- COST -- RECOMMENDATIONS -- 4 Community Prevention Study -- INTRODUCTION -- RATIONALE -- DESIGN AND METHODS -- COST -- RECOMMENDATIONS -- 5 Concluding Remarks -- RESPONSE TO THE STATEMENT OF TASK -- SOCIETAL CONTEXT -- Efficacy and Effectiveness -- Public Health Choice versus Individual Choice -- Considerations beyond Science -- References -- Appendixes -- A Clinical Trial Exclusion Criteria (June 28, 1993, WHI Protocol) -- A.  EXCLUSION CRITERIA FOR ALL COMPONENTS -- B.  ADDITIONAL EXCLUSION CRITERIA FOR ALL CLINICAL TRIAL COMPONENTS -- C.  ADDITIONAL EXCLUSION CRITERIA FOR HORMONE REPLACEMENT COMPONENT -- D.  ADDITIONAL EXCLUSION CRITERIA FOR DIETARY MODIFICATION COMPONENT -- E.  ADDITIONAL EXCLUSION CRITERIA FOR CALCIUM/VITAMIN D COMPONENT. 327 $aB U.S. House of Representatives Appropriations Committee -- C Statement of Task -- D Documents Received by the Institute of Medicine from the National Institutes of Health -- E Meeting Participants June, July, and August 1993 -- F Primary and Subsidiary Hypotheses of the Women's Health Initiative Clinical Trial -- G Women's Health Initiative Committees -- H NIH-Sponsored Women's Health Studies -- I NIH Cost and FTE Summary for Vanguard Clinical Centers -- J NIH Power Calculations -- K Women's Health Initiative Clinical Coordinating Center and Vanguard Clinical Centers Principal Investigators -- M Committee and Staff Biographies -- IOM STAFF. 330 $aThe National Institutes of Health Women's Health Initiative (WHI) is the largest research study ever funded by NIH ($625 million over 14 years) and is designed to test strategies to prevent cardiovascular disease, breast cancer, and osteoporotic fractures--leading causes of death, disability, and decreased quality of life for older women. Although the WHI has already begun, serious questions remain about its design, cost, and the likelihood that it can answer the questions it asks. This book evaluates whether the effort can be justified scientifically. 606 $aWomen$xHealth and hygiene$zUnited States 615 0$aWomen$xHealth and hygiene 676 $a613/.04244/0973 701 $aThaul$b Susan$01806764 701 $aHotra$b Dana$01806765 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910965693103321 996 $aAn assessment of the NIH Women's Health Initiative$94356127 997 $aUNINA