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100   $a20100623d2010      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aInteractions of herbicide atrazine with DNA /$fMaria Hepel and Magdalena Stobiecka
205   $a1st ed.
210   $aNew York $cNova Science Publishers$dc2010
215   $a1 online resource (76 p.)
225 1 $aDNA: properties and modifications, functions and interactions, recombination and applications.
225 1 $aEnvironmental science, engineering and technology.
300   $aDescription based upon print version of record.
311 08$a1-61728-908-6 
320   $aIncludes bibliographical references and index.
327   $aIntro -- INTERACTIONS OF HERBICIDE ATRAZINE WITH DNA -- INTERACTIONS OF HERBICIDE ATRAZINE WITH DNA -- Contents -- Preface -- Chapter I   Introduction -- Chapter II    Materials and Methods -- 2.1. Chemicals -- 2.2. APPARATUS -- 2.3. PREPARATION OF BIOSENSORS -- QC/Au/Cit/PLL/ctDNA Sensor -- QC/Au/MPA/DNA20 bp -- QC/Au/AET/AuNP@MPA/dsDNA20 bp -- 2.4. PROCEDURES -- Cleaning of Gold Disk Electrodes -- Synthesis of Gold Nanoparticles -- DNA Damage Testing -- Voltammetric Measurements -- Ab-Initio Calculations -- Chapter III   Results and Discussion -- 3.1. Design of Hybridization Biosensors for Investigations of DNA Damage by Toxicants -- 3.2. INTERACTIONS OF ATRAZINE  WITH DNA IN SOLUTION -- 3.3. Vertical Short-Chain DNA Biosensors for Atrazine Intercalation Measurements -- 3.4. Interactions of Atrazine with  DNA-Modified Gold Nanoparticles -- 3.5. Interactions of Atrazine with DNA-Modified Nanostructured Piezosensors -- 3.6. New Ferrocene-Modified DNA Biosensors for Comparative Analysis of DNA Damage Caused by Herbicides and Pesticides -- 3.7. Kinetics of DNA Damage  and Unwinding -- 3.8. Theoretical Bases of Atrazine Interactions with DNA Double-Helix -- Chapter IV   Conclusion -- References -- Index -- Blank Page.
330   $aNew methods used for the detection of DNA hybridization process, including electrochemical, optical scattering, surface plasmon resonance, nanogravimetric, and fluorimetric are described and their application in assays assessing DNA damage is discussed in this book. The analyses of damage and alterations for the DNA in solution as well as for the DNA immobilized on core-shell gold nanoparticles and solid electrodes are presented. These methods enable evaluating the degree of DNA damage caused by toxicants and can be applied to studies of the interactions of atrazine and other herbicides and pesticides with DNA.
410  0$aDNA--properties and modifications, functions and interactions, recombination and applications series.
410  0$aEnvironmental science, engineering and technology series.
606   $aDNA-drug interactions
606   $aAtrazine$xToxicology
606   $aBiosensors
606   $aEnvironmental monitoring$xMethodology
615  0$aDNA-drug interactions.
615  0$aAtrazine$xToxicology.
615  0$aBiosensors.
615  0$aEnvironmental monitoring$xMethodology.
676   $a572.8/6
700   $aHepel$b Maria$01871693
701   $aStobiecka$b Magdalena$01871694
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910965265403321
996   $aInteractions of herbicide atrazine with DNA$94480612
997   $aUNINA