LEADER 03131oam 22005413 450 001 9910964928103321 005 20251017110112.0 010 $a0-309-45029-2 010 $a0-309-45027-6 035 $a(CKB)3710000001064498 035 $a(MiAaPQ)EBC4806755 035 $a(DNLM)1701576 035 $a(EXLCZ)993710000001064498 100 $a20240208d2017 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aDeveloping Multimodal Therapies for Brain Disorders $eProceedings of a Workshop 205 $a1st ed. 210 1$aWashington, D.C. :$cNational Academies Press,$d2017. 210 4$dİ2017. 215 $a1 online resource (97 pages) 311 08$a0-309-45026-8 327 $aIntroduction -- Multimodal therapy: overview of principles, barriers, and opportunities -- Exploring the state of the science -- Exploring the state of the science -- Regulatory and reimbursement considerations -- Trial designs to establish efficacy and safety in multimodal therapies -- Developing multimodal therapies: practical considerations relating to industry -- Role of research funders in multimodal therapy development -- Appendix A: References -- Appendix B: Workshop agenda -- Appendix C: Registered participants. 330 $a"Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potential--and perhaps essential--ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal therapies and to explore challenges, potential barriers, and opportunities for their development, the National Academies of Sciences, Engineering, and Medicine convened a workshop in June 2016. Participants explored scientific, clinical, regulatory, and reimbursement issues related to multimodal approaches and potential opportunities to enhance clinical outcomes for individuals with nervous system disorders. This publication summarizes the presentations and discussions from the workshop"--Publisher's description. 606 $aBrain$xDiseases$xAdjuvant treatment$vCongresses 606 $aCombined modality therapy$vCongresses 606 $aCombined Modality Therapy 606 $aBrain Diseases$xtherapy 615 0$aBrain$xDiseases$xAdjuvant treatment 615 0$aCombined modality therapy 615 12$aCombined Modality Therapy. 615 12$aBrain Diseases$xtherapy. 676 $a616.8/046 700 $aStroud$b Clare$01601279 701 $aKeren$b Noam I$01852304 701 $aBain$b Lisa$01852305 712 02$aNational Academies of Sciences, Engineering, and Medicine (U.S.).$bForum on Neuroscience and Nervous System Disorders, 712 12$aMultimodal Therapies for Brain Disorders (Workshop)$f(2016 :$eWashington, D.C.),$bauthor. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910964928103321 996 $aDeveloping Multimodal Therapies for Brain Disorders$94447274 997 $aUNINA