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100   $a20100813d2011      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aComputational metabolomics /$fNabil Semmar
205   $a1st ed.
210   $aNew York $cNova Science Publishers$dc2011
215   $a1 online resource (250 p.)
225 1 $aMetabolic diseases--laboratory and clinical research
300   $aDescription based upon print version of record.
311 08$a1-61761-608-7 
320   $aIncludes bibliographical references (p. [213]-232) and index.
327   $aGeneral classification of metabolomic approaches -- Stoichiometry-based approaches -- Correlation-based approaches -- Distances- and similarity indices-based approaches : cluster analysis -- Outliers and extreme cases analysis -- Weighted metabolic profiles analysis -- Time-dependent analysis of metabolic systems.
330   $aMetabolism represents a complex system characterised by a high variability in metabolites' structure, concentration and regulation ratio. Such variability is observed at different metabolic scales going from metabolites to metabolic profiles via chemical reactions and metabolic pathways, as well as under static or dynamic aspects. Variations in these components are due to apparition-disappearance, level increase-decrease and/or relative changes in weights or contributions leading to different structural, functional and evolutive states of the metabolic system. This book presents a variety of different computational approaches of the variability in metabolic systems.
410  0$aMetabolic diseases--laboratory and clinical research series.
606   $aMetabolites
615  0$aMetabolites.
676   $a570.285
700   $aSemmar$b Nabil$01681961
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910964470103321
996   $aComputational metabolomics$94469332
997   $aUNINA