LEADER 05501nam 2200685 450 001 9910140484103321 005 20170822101630.0 010 $a1-118-85481-0 010 $a1-118-85475-6 010 $a1-118-85477-2 035 $a(CKB)2670000000583823 035 $a(EBL)1873191 035 $a(OCoLC)897448905 035 $a(SSID)ssj0001380985 035 $a(PQKBManifestationID)11803469 035 $a(PQKBTitleCode)TC0001380985 035 $a(PQKBWorkID)11393236 035 $a(PQKB)10549127 035 $a(MiAaPQ)EBC1873191 035 $a(PPN)224476386 035 $a(EXLCZ)992670000000583823 100 $a20140811h20152015 uy| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 04$aThe chemistry of molecular imaging /$fedited by Nicholas Long, Wing-Tak Wong 210 1$aHoboken, New Jersey :$cWiley,$d[2015] 210 4$dİ2015 215 $a1 online resource (434 p.) 300 $aDescription based upon print version of record. 311 $a1-118-09327-5 311 $a1-322-43948-6 320 $aIncludes bibliographical references and index. 327 $aThe Chemistry of Molecular Imaging; Copyright; Contents; Preface; List of Contributors; Chapter 1 An Introduction to Molecular Imaging; 1.1 Introduction; 1.2 What is Positron Emission Tomography (PET)?; 1.2.1 Basic Principles; 1.2.2 Advantages and Limitations; 1.3 What is Single Photon Emission Computed Tomography (SPECT)?; 1.3.1 Basic Principles; 1.3.2 Advantages and Limitations; 1.4 What is Computed Tomography (CT) or Computed Axial Tomography (CAT)?; 1.4.1 Basic Principles; 1.4.2 Advantages and Limitations; 1.5 What is Magnetic Resonance Imaging (MRI)?; 1.5.1 Basic Principles 327 $a1.5.2 Advantages and Limitations1.6 What is Optical Imaging?; 1.6.1 Basic Principles; 1.6.2 Conventional or Wide-Field Fluorescence Microscopy; 1.6.3 Confocal Microscopy or Confocal Laser Scanning Microscopy; 1.6.4 Advantages and Limitations; 1.7 What is Ultrasound (US)?; 1.7.1 Basic Principles; 1.7.2 Advantages and Limitations; 1.8 Conclusions; References; Chapter 2 Chemical Methodology for Labelling and Bioconjugation; 2.1 Introduction; 2.2 Chemical Methods; 2.2.1 Through Reactions with Aldehydes or Ketones; 2.2.2 Through Reactions with Azides; 2.2.3 Through Reactions with Alkenes 327 $a2.2.4 Cross-Coupling Reactions2.3 Site-Specific Modification of Proteins or Peptides; 2.3.1 N-terminal Cysteine; 2.3.2 Aromatic Residues; 2.3.3 N-terminus of Protein; 2.3.4 C-terminus of Protein; 2.3.5 Introduction of Chemical Tags for Site-Specific Labelling on Peptides or Proteins; 2.4 Conclusions; References; Chapter 3 Recent Developments in the Chemistry of [18F]Fluoride for PET; 3.1 Introduction; 3.2 Fluorine-18: The Starting Material; 3.3 Reactive [18F]Fluoride; 3.4 The Radiofluorination; 3.4.1 Electrophilic Reactions; 3.4.2 Nucleophilic Reactions 327 $a3.5 Labelling of Large Biological Molecules3.5.1 The Prosthetic Group Concept; 3.5.2 Prosthetic Entities with Fluorine-18 Bound to Aluminium, Boron, or Silicon; 3.5.3 Click Chemistry; 3.6 Conclusions; References; Chapter 4 Carbon-11, Nitrogen-13, and Oxygen-15 Chemistry: An Introduction to Chemistry with Short-Lived Radioisotopes; 4.1 Introduction; 4.2 Carbon-11 Chemistry; 4.2.1 Synthesis with [11C]Carbon Dioxide; 4.2.2 [11C]methylation Reactions; 4.2.3 [11C]Phosgene Reactions; 4.2.4 [11C]Cyanation Reactions; 4.2.5 [11C]Carbonylation Reactions; 4.3 Nitrogen-13 Chemistry 327 $a4.3.1 Synthesis of 13N-labelled Amines4.3.2 Enzymatic Synthesis of 13N-labelled Amino Acid; 4.3.3 Synthesis of [13N]cisplatin; 4.3.4 Synthesis of [13N] Carbamates and Ureas; 4.3.5 Other 13N-labelling Reactions; 4.4 Oxygen-15 Chemistry; 4.5 Conclusions; References; Chapter 5 The Chemistry of Inorganic Nuclides (86Y, 68Ga, 64Cu, 89Zr, 124I); 5.1 Introduction: Inorganic Nuclide-Based Radiopharmaceuticals; 5.2 Radiopharmaceutical Design; 5.3 Radiopharmaceutical Stability; 5.4 86Yttrium Radiometal Ion Properties; 5.4.1 Clinical Trials Based on 86Yttrium; 5.4.2 Recent 86Yttrium Work 327 $a5.4.3 Stability of 86Yttrium-Based Radiopharmaceuticals 330 $a"Covering all the fundamentals of modern imaging methodologies, including their techniques and application within medicine and industry, The Chemistry of Molecular Engineering focuses primarily on the chemistry of probes and imaging agents, as well as chemical methodology for labelling and bioconjugation. Written by an interdisciplinary team of experts, this book investigates the chemistry of molecular imaging and helps to educate non-chemists already involved in the area of molecular imaging. It addresses all the major modalities and techniques, such as MRI, positron emission tomography, single photon emission computed tomography, ultrasound, and fluorescence/optical imaging"--$cProvided by publisher. 606 $aImaging systems 606 $aImaging systems in medicine 606 $aMolecular probes 615 0$aImaging systems. 615 0$aImaging systems in medicine. 615 0$aMolecular probes. 676 $a616.07 676 $a616.07540154 686 $aTEC015000$2bisacsh 702 $aLong$b Nicholas J.$f1965- 702 $aWong$b Wing-Tak 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910140484103321 996 $aThe chemistry of molecular imaging$92006636 997 $aUNINA LEADER 03011nam 2200649Ia 450 001 9910963775803321 005 20200520144314.0 010 $a9781438415178 010 $a1438415176 010 $a9780585088365 010 $a0585088365 035 $a(CKB)111004365683598 035 $a(OCoLC)43475808 035 $a(CaPaEBR)ebrary10588670 035 $a(SSID)ssj0000184314 035 $a(PQKBManifestationID)11183711 035 $a(PQKBTitleCode)TC0000184314 035 $a(PQKBWorkID)10200081 035 $a(PQKB)11099231 035 $a(MdBmJHUP)muse13960 035 $a(Au-PeEL)EBL3408123 035 $a(CaPaEBR)ebr10588670 035 $a(MiAaPQ)EBC3408123 035 $a(DE-B1597)735577 035 $a(DE-B1597)9781438415178 035 $a(Perlego)2673812 035 $a(EXLCZ)99111004365683598 100 $a19801007d1981 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aIsraeli humor $ethe content and structure of the chizbat of the Palmah /$fElliott Oring 205 $a1st ed. 210 $aAlbany $cState University of New York Press$dc1981 215 $a1 online resource (ix, 295 pages) 225 0 $aSUNY series in Modern Jewish Literature and Culture 225 0$aSUNY series in modern Jewish literature and culture 311 08$a9780873955133 311 08$a0873955137 311 08$a9780873955126 311 08$a0873955129 320 $aIncludes bibliographical references and indexes. 327 $aHa-Palmah Ha-Chizbat The argument of humor The content The structure The message Kezavim 330 $aDerived from the Arabic word for "lie," the word "chizbat" was chosen by members of the Palmah to designate the particular form of narrative joke exchanged by these volunteer defenders of Jewish settlements in Israel during the uncertain years 1941-48. Elliott Oring concentrates his attention on how the chizbat represents the expression of a distinctly Israeli identity and the disparate elements of this identity: sabra/European, Arab/Israeli, East/West. He shows how chizbat humor depends, not so much on novelty or punch line, as on displaying these incongruities of Israeli identity. Oring also discusses the sociocultural context in which the chizbat developed and examines how various theories of humor apply to understanding the chizbat. In an appendix invaluable for the folklorist, Oring has translated hundreds of chizbat into English. some are from written sources and others are verbal accounts he obtained during his months of research in Israel. 606 $aIsraeli wit and humor$xHistory and criticism 615 0$aIsraeli wit and humor$xHistory and criticism. 676 $a398.2/095694 700 $aOring$b Elliott$f1945-$0449883 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910963775803321 996 $aIsraeli humor$94344671 997 $aUNINA