LEADER 01682nas 2200541- 450 001 9910208860303321 005 20210913213021.0 011 $a0718-2279 035 $a(OCoLC)818948702 035 $a(CKB)1000000000312466 035 $a(CONSER)--2015240222 035 $a(EXLCZ)991000000000312466 100 $a20121106a20059999 --- - 101 0 $aspa 135 $aurmn|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aAnuario de derechos humanos 210 1$aSantiago de Chile :$cCentro de Derechos Humanos, Facultad de Derecho, Universidad de Chile,$d2005- 215 $a1 online resource 300 $aRefereed/Peer-reviewed 311 08$a0718-2058 531 0 $aAnu. derechos hum. 606 $aCivil rights$zChile$vPeriodicals 606 $aCivil rights$zLatin America$vPeriodicals 606 $aHuman rights$zChile$vPeriodicals 606 $aHuman rights$zLatin America$vPeriodicals 606 $aCivil rights$vPeriodicals 606 $aHuman rights$vPeriodicals 606 $aCivil rights$2fast$3(OCoLC)fst00862627 606 $aHuman rights$2fast$3(OCoLC)fst00963285 607 $aChile$2fast 607 $aLatin America$2fast 608 $aPeriodicals.$2fast 615 0$aCivil rights 615 0$aCivil rights 615 0$aHuman rights 615 0$aHuman rights 615 0$aCivil rights 615 0$aHuman rights 615 7$aCivil rights. 615 7$aHuman rights. 712 02$aUniversidad de Chile.$bCentro de Derechos Humanos. 906 $aJOURNAL 912 $a9910208860303321 996 $aAnuario de derechos humanos$92158135 997 $aUNINA LEADER 03584nam 2200685 a 450 001 9910963416303321 005 20251017110118.0 010 $a0-309-20959-5 010 $a1-283-01910-8 010 $a9786613019103 010 $a0-309-15890-7 035 $a(CKB)2550000000032026 035 $a(EBL)3378748 035 $a(SSID)ssj0000507437 035 $a(PQKBManifestationID)11344055 035 $a(PQKBTitleCode)TC0000507437 035 $a(PQKBWorkID)10562131 035 $a(PQKB)10436788 035 $a(MiAaPQ)EBC3378748 035 $a(Au-PeEL)EBL3378748 035 $a(CaPaEBR)ebr10454969 035 $a(CaONFJC)MIL301910 035 $a(OCoLC)923283190 035 $a(DNLM)1559514 035 $a(EXLCZ)992550000000032026 100 $a20110414d2011 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBuilding a national framework for the establishment of regulatory science for drug development $eworkshop summary /$fInstitute of Medicine of the National Academies ; Yeonwoo Lebovitz, Rebecca A. English, and Anne B. Claiborne, rapporteurs 205 $aFirst edition. 210 $aWashington, D.C. $cNational Academies Press$d2011 215 $a1 online resource (95 pages) 300 $a"Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy." 311 08$a0-309-15889-3 320 $aIncludes bibliographical references. 327 $a""Front Matter""; ""Reviewers""; ""Contents""; ""Figures and Boxes""; ""Acronyms""; ""Preface""; ""1 Introduction""; ""2 Defining Regulatory Science""; ""3 The Urgent Need for Regulatory Science""; ""4 Barriers to Enhanced Regulatory Science""; ""5 Potential Models for Building a Regulatory Science Infrastructure""; ""6 Challenges in Engaging the Public Policy Community""; ""7 Envisioning Successful Regulatory Science at FDA""; ""8 Considering Next Steps""; ""References""; ""Appendix A: Agenda""; ""Appendix B: Participant Biographies"" 330 $a"The Food and Drug Administration (FDA) is tasked with ensuring the safety and effectiveness of medicine. FDA's science base must be strong enough to make certain that regulatory decisions are based on the best scientific evidence. The IOM held a public workshop on February 26, 2010, to examine the state of regulatory science and to consider approaches for enhancing it."--Publisher's description. 606 $aPharmaceutical policy$zUnited States$vCongresses 606 $aDrug development$xGovernment policy$zUnited States$vCongresses 606 $aPharmaceutical industry$xGovernment policy$zUnited States$vCongresses 615 0$aPharmaceutical policy 615 0$aDrug development$xGovernment policy 615 0$aPharmaceutical industry$xGovernment policy 676 $a615.1 701 $aLebovitz$b Yeonwoo$01807991 701 $aEnglish$b Rebecca A$01805913 701 $aClaiborne$b Anne B$01805914 712 02$aInstitute of Medicine (U.S.).$bForum on Drug Discovery, Development, and Translation. 712 02$aInstitute of Medicine (U.S.).$bBoard on Health Sciences Policy. 712 12$aBuilding a National Framework for the Establishment of Regulatory Science for Drug Development$f(2010 :$eWashington, D.C.) 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910963416303321 996 $aBuilding a national framework for the establishment of regulatory science for drug development$94447240 997 $aUNINA LEADER 04598nam 2200721Ia 450 001 9910958552903321 005 20250704110113.0 010 $a9781611926705 010 $a161192670X 010 $a9781611922684 010 $a1611922682 035 $a(CKB)2670000000185636 035 $a(EBL)3115154 035 $a(SSID)ssj0000674603 035 $a(PQKBManifestationID)12347125 035 $a(PQKBTitleCode)TC0000674603 035 $a(PQKBWorkID)10669356 035 $a(PQKB)11597464 035 $a(Au-PeEL)EBL3115154 035 $a(CaPaEBR)ebr10555592 035 $a(OCoLC)922965527 035 $a(MiAaPQ)EBC3115154 035 $a(MiFhGG)9781611922684 035 $a(Perlego)2968725 035 $a(NyNyDIG)DIGARTEP0059 035 $a(EXLCZ)992670000000185636 100 $a20080410d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aRecovering the U.S. Hispanic linguistic heritage $esociohistorical approaches to Spanish in the United States /$fedited by Alejandra Balestra, Glenn Martinez and Maria Irene Moyna 205 $a1st ed. 210 $aHouston, Tex. $cArte Publico Press$dc2008 215 $a1 online resource (225 p.) 225 1 $aRecovering the U.S. Hispanic literary heritage 300 $aDescription based upon print version of record. 311 08$a9781558855281 311 08$a1558855289 320 $aIncludes bibliographical references. 327 $a""Espinosaa???s Diary Chronicling the 1716 RamA?³n Expedition into Texas: Notes on the Translations*""""La expresiA?³n de la pasividad en California en el siglo XIX""; ""Language Wars on the Texas Frontier""; ""How the Californio Girls (and Boys) Lost Their Accents""; ""Dialect Death:The Case of AdaeseA?±o Spanish in Northwest Louisiana""; ""Contributors"" 330 8 $aContrary to popular belief, the first European language spoken on American soil was not English, but Spanish. Explorer Alvar Nu?n?ez Cabeza de Vaca and his shipmates landed on the Florida coast in 1513, almost 100 years before the British established a permanent settlement in Virginia. In this fascinating exploration of the development of the Spanish language from a sociohistorical perspective in the territory that has become the United States, linguists and editors Balestra, Marti?nez, and Moyna draw attention to the long tradition of multilingualism in the United States in the hope of putting to rest the myth that the U.S. was ever a monolingual nation. The book is divided into two parts: an extensive introduction and a collection of seven articles about various aspects of the sociohistorical development of Spanish. The in-depth introduction gives the reader a historical overview of the areas of the U.S. previously occupied by Spain and Mexico, from the arrival of the earliest settlers to the Mexican-American War and the Treaty of Guadalupe Hidalgo. The introduction also reviews language policies during the colonial and Mexican periods as well as current linguistic approaches, census data, and sociolinguistic research. In addition to shedding light on the linguistic evolution of Spanish in the U.S., the seven papers included in the second section of this volume offer the reader a fascinating glimpse into historical ideologies and beliefs in the territory that has become the United States. A truly multidisciplinary book that touches on a number of related fields, Recovering the U.S. Hispanic Linguistic Heritage will be a must-read for scholars of history, sociology, and linguistics and anyone interested in the evolution of the Spanish influence and language in the U.S. 410 0$aRecovering the U.S. Hispanic Literary Heritage Project publication. 606 $aHispanic Americans$xLanguages 606 $aSpanish language$xSocial aspects$zUnited States 606 $aSpanish language$xStudy and teaching$zUnited States$xHistory 606 $aSpanish language$zUnited States$xHistory 615 0$aHispanic Americans$xLanguages. 615 0$aSpanish language$xSocial aspects 615 0$aSpanish language$xStudy and teaching$xHistory. 615 0$aSpanish language$xHistory. 676 $a467/.973 701 $aBalestra$b Alejandra$01787358 701 $aMarti?nez$b Glenn A.$f1971-$01787359 701 $aMoyna$b Mari?a Irene$01787357 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910958552903321 996 $aRecovering the U.S. Hispanic linguistic heritage$94320749 997 $aUNINA