LEADER 00917nam0-22003011i-450- 001 990000101450403321 035 $a000010145 035 $aFED01000010145 035 $a(Aleph)000010145FED01 035 $a000010145 100 $a20011111d--------km-y0itay50------ba 101 0 $aita 105 $ay-------001yy 200 1 $aHorizontal wells$ea new application of geological principles to effects the solution of the problem of supplyng Londonwith pure water$fJ. Lucas. 210 $aLondon$cE. Stanford$d1874 215 $aVIII, 86 p., 5 tav.$cill.$d26 cm 610 0 $aAcque potabili$aApprovigionamento 610 0 $aPozzi d'acqua 676 $a628.114 700 1$aLucas,$bJ.$0332997 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990000101450403321 952 $a13 AR 21 E 19$b4075$fFINBC 959 $aFINBC 996 $aHorizontal wells$9116233 997 $aUNINA DB $aING01 LEADER 03584nam 2200685 a 450 001 9910963416303321 005 20251017110118.0 010 $a0-309-20959-5 010 $a1-283-01910-8 010 $a9786613019103 010 $a0-309-15890-7 035 $a(CKB)2550000000032026 035 $a(EBL)3378748 035 $a(SSID)ssj0000507437 035 $a(PQKBManifestationID)11344055 035 $a(PQKBTitleCode)TC0000507437 035 $a(PQKBWorkID)10562131 035 $a(PQKB)10436788 035 $a(MiAaPQ)EBC3378748 035 $a(Au-PeEL)EBL3378748 035 $a(CaPaEBR)ebr10454969 035 $a(CaONFJC)MIL301910 035 $a(OCoLC)923283190 035 $a(DNLM)1559514 035 $a(EXLCZ)992550000000032026 100 $a20110414d2011 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBuilding a national framework for the establishment of regulatory science for drug development $eworkshop summary /$fInstitute of Medicine of the National Academies ; Yeonwoo Lebovitz, Rebecca A. English, and Anne B. Claiborne, rapporteurs 205 $aFirst edition. 210 $aWashington, D.C. $cNational Academies Press$d2011 215 $a1 online resource (95 pages) 300 $a"Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy." 311 08$a0-309-15889-3 320 $aIncludes bibliographical references. 327 $a""Front Matter""; ""Reviewers""; ""Contents""; ""Figures and Boxes""; ""Acronyms""; ""Preface""; ""1 Introduction""; ""2 Defining Regulatory Science""; ""3 The Urgent Need for Regulatory Science""; ""4 Barriers to Enhanced Regulatory Science""; ""5 Potential Models for Building a Regulatory Science Infrastructure""; ""6 Challenges in Engaging the Public Policy Community""; ""7 Envisioning Successful Regulatory Science at FDA""; ""8 Considering Next Steps""; ""References""; ""Appendix A: Agenda""; ""Appendix B: Participant Biographies"" 330 $a"The Food and Drug Administration (FDA) is tasked with ensuring the safety and effectiveness of medicine. FDA's science base must be strong enough to make certain that regulatory decisions are based on the best scientific evidence. The IOM held a public workshop on February 26, 2010, to examine the state of regulatory science and to consider approaches for enhancing it."--Publisher's description. 606 $aPharmaceutical policy$zUnited States$vCongresses 606 $aDrug development$xGovernment policy$zUnited States$vCongresses 606 $aPharmaceutical industry$xGovernment policy$zUnited States$vCongresses 615 0$aPharmaceutical policy 615 0$aDrug development$xGovernment policy 615 0$aPharmaceutical industry$xGovernment policy 676 $a615.1 701 $aLebovitz$b Yeonwoo$01807991 701 $aEnglish$b Rebecca A$01805913 701 $aClaiborne$b Anne B$01805914 712 02$aInstitute of Medicine (U.S.).$bForum on Drug Discovery, Development, and Translation. 712 02$aInstitute of Medicine (U.S.).$bBoard on Health Sciences Policy. 712 12$aBuilding a National Framework for the Establishment of Regulatory Science for Drug Development$f(2010 :$eWashington, D.C.) 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910963416303321 996 $aBuilding a national framework for the establishment of regulatory science for drug development$94447240 997 $aUNINA