LEADER 02546nam 2200625 a 450 001 9910962608403321 005 20251117063834.0 010 $a9781788018302 010 $a1788018303 010 $a9781847550927 010 $a1847550924 035 $a(CKB)1000000000791329 035 $a(EBL)1185543 035 $a(SSID)ssj0000379365 035 $a(PQKBManifestationID)11271602 035 $a(PQKBTitleCode)TC0000379365 035 $a(PQKBWorkID)10366565 035 $a(PQKB)11751198 035 $a(MiAaPQ)EBC1185543 035 $a(Au-PeEL)EBL1185543 035 $a(CaPaEBR)ebr10621251 035 $a(OCoLC)843641287 035 $a(PPN)198478321 035 $a(MiAaPQ)EBC7423245 035 $a(Au-PeEL)EBL7423245 035 $a(Perlego)787341 035 $a(iGPub)CSPLUS0082225 035 $a(EXLCZ)991000000000791329 100 $a20040702d2003 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aFree energy relationships in organic and bio-organic chemistry /$fAndrew Williams 205 $a1st ed. 210 $aCambridge, U.K. $cRSC$dc2003 215 $a1 online resource (313 p.) 300 $aDescription based upon print version of record. 311 08$a9780854046768 311 08$a0854046763 320 $aIncludes bibliographical references and index. 327 $a01PRELIM; 02PREFA; 03CONT; 04CHAP01; 05CHAP02; 06CHAP03; 07CHAP04; 08CHAP05; 09CHAP06; 10CHAP07; 11APPEN1; 12APPEN2; 13APPEN3; 14APPEN4; 15INDEX 330 $aIntroducing the application of free energy correlations to elucidating the mechanisms of organic and bio-organic reactions, this book provides a new and illuminating way of approaching a potentially complex topic. The idea of how free energy correlations derive from polar substituent change is introduced, and common pitfalls encountered in the application of free energy relationships are described, along with the use of these anomalies in mechanistic studies. The concept of effective charge is described in detail, with examples of its application. Throughout, worked answers are provided for th 606 $aLinear free energy relationship 615 0$aLinear free energy relationship. 676 $a547.139 700 $aWilliams$b Andrew$f1937-$01896520 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910962608403321 996 $aFree energy relationships in organic and bio-organic chemistry$94551205 997 $aUNINA