LEADER 03214nam 2200661 a 450 001 9910962058303321 005 20251017110115.0 010 $a0-309-20961-7 010 $a1-283-01913-2 010 $a9786613019134 010 $a0-309-16183-5 035 $a(CKB)2550000000032005 035 $a(SSID)ssj0000536379 035 $a(PQKBManifestationID)11325251 035 $a(PQKBTitleCode)TC0000536379 035 $a(PQKBWorkID)10549347 035 $a(PQKB)10134841 035 $a(MiAaPQ)EBC3378741 035 $a(Au-PeEL)EBL3378741 035 $a(CaPaEBR)ebr10454959 035 $a(CaONFJC)MIL301913 035 $a(OCoLC)923283111 035 $a(DNLM)1559226 035 $a(EXLCZ)992550000000032005 100 $a20110408d2011 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aEstablishing precompetitive collaborations to stimulate genomics-driven product development $eworkshop summary /$fInstitute of Medicine of the National Academies ; Steve Olson and Adam C. Berger, rapporteurs 205 $a1st ed. 210 $aWashington, D.C. $cNational Academies Press$d2011 215 $axv, 74 p. $cill. (some col.) 300 $a"Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy." 311 08$a0-309-16182-7 320 $aIncludes bibliographical references. 327 $aIntroduction -- A lesson about precompetitive collaboration -- Requisites for successful precompetitive collaboration -- Frameworks for collaboration -- The use of biospecimens in precompetitive collaborations -- Ethical challenges in the use of biospecimens -- Toward developing a cultural, legal, and behavioral framework for precompetitive collaboration. 330 $a"Despite the many basic research discoveries in genetics, relatively few gene-based treatments, drugs, or preventative measures have been developed. One way to bridge this gap may be for industry, academia, and government to develop partnerships that share resources while distributing risk. However, intellectual property protections and other barriers can inhibit collaborative efforts. The Institute of Medicine held a workshop on July 22, 2010, to explore these issues and develop solutions."--Publisher's description. 606 $aPharmacogenetics$vCongresses 606 $aDrug development$vCongresses 606 $aGenomics$vCongresses 615 0$aPharmacogenetics 615 0$aDrug development 615 0$aGenomics 676 $a576.5 701 $aOlsen$b Steven$01602366 701 $aBerger$b Adam C$01120088 712 02$aInstitute of Medicine (U.S.).$bRoundtable on Translating Genomic-Based Research for Health. 712 02$aInstitute of Medicine (U.S.).$bBoard on Health Sciences Policy. 712 12$aEstablishing Precompetitive Collaborations to stimulate genomics-driven product development$f(2010 :$eWashington, D.C.) 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910962058303321 996 $aEstablishing precompetitive collaborations to stimulate genomics-driven product development$94446262 997 $aUNINA LEADER 04747nam 22005415 450 001 9910253898603321 005 20200702131354.0 010 $a3-319-42004-6 024 7 $a10.1007/978-3-319-42004-2 035 $a(CKB)3710000000829701 035 $a(DE-He213)978-3-319-42004-2 035 $a(MiAaPQ)EBC4648170 035 $a(PPN)19480464X 035 $a(EXLCZ)993710000000829701 100 $a20160816d2016 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAllergy and Respiration /$fedited by Mieczyslaw Pokorski 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (VIII, 87 p.) 225 1 $aNeuroscience and Respiration ;$v921 311 $a3-319-42003-8 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aChapter 1. Spirometry or Body Plethysmography for the Assessment of Bronchial Hyperresponsiveness, R. Merget, F. Nensa, E. Heinze, D. Taeger, T. Bruening -- Chapter 2. Clinical Effects, Exhaled Breath Condensate pH and Exhaled Nitric Oxide in Humans after Ethyl Acrylate Exposure, F. Hoffmeyer, J. Bünger, C. Monsé, H. Berresheim, B. Jettkant, A. Beine, T. Brüning, K. Sucker -- Chapter 3. Effectiveness of PCR and Immunofluorescence Techniques for Detecting Human Cytomegalovirus in Blood and Bronchoalveolar Lavage Fluid, A. Ro?y, K. Duk, B. Szumna, P. Jagu?, D. Gawryluk, J. Chorostowska-Wynimko -- Chapter 4. The Role of Ion Channels to Regulate Airway Ciliary Beat Frequency During Allergic Inflammation, M. Joskova, M. Sutovska, P. Durdik, D. Koniar, L. Hargas, P. Banovcin, M. Hrianka, V. Khazaei, L. Pappova, S. Franova -- Chapter 5. Content of Asthmagen Natural Rubber Latex Allergens in Commercial Disposable Gloves, C. Bittner, M. Velasco Garrido, L.H. Krach, V. Harth -- Chapter 6. Thermal Sensitivity and Dimethyl Sulfoxide (DMSO), K. Takeda, M. Pokorski, Y. Okada -- Chapter 7. IgE Reactivity, Work Related Allergic Symptoms, Asthma Severity, and Quality of Life in Bakers with Occupational Asthma, C. Bittner, M. Velasco Garrido, V. Harth, A.M. Preisser -- Chapter 8. Effects of Selective Inhibition of PDE4 by YM976 on Airway Reactivity and Cough in Ovalbumin-Sensitized Guinea Pigs, J. Mokrý, A. Fulmeková, I. Medvedová, M. Kertys, P. Mikolka, P. Kosutová, D. Mokrá -- Chapter 9. Airway Defense Control Mediated via Voltage-Gated Sodium Channels, M. Kocmalova, M. Joskova, S. Franova, P. Banovcin, M. Sutovska -- Chapter 10 -- Virological Characteristics of the 2014/2015 Influenza Season Based on Molecular Analysis of Biological Material Derived from I-MOVE, E. Hallmann-Szeli?ska, K. Bednarska, M. Korczy?ska, I. Paradowska-Stankiewicz, L.B. Brydak. 330 $aAllergy is an increasing health issue. It often targets the respiratory tract and entwines with respiratory ailments, which makes it difficult to discern the cause-effect linkage. Nonetheless, measures to counter the allergic background are a linchpin in preserving respiratory health. This book is an update on current advances in clinical and basic science on allergy and related topics. The diagnostics of allergy requires a multidisciplinary approach, including molecular examinations aimed at unraveling the intracellular control cascades. Chapters give insight into the innovations concerning modern pulmonary function tests, discuss pharmacological paradigms, and tackle the overlapping infectious aspects and clinical symptoms and markers. Environmental and genetic factors elicit a spectrum of inflammatory phenotypes linked to differential body responses to allergic perturbations. The book is intended for healthcare professionals, notably pulmonologists, primary care physicians, and medical researchers. . 410 0$aNeuroscience and Respiration ;$v921 606 $aPharmacology 606 $aAllergy 606 $aCytology 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 606 $aAllergology$3https://scigraph.springernature.com/ontologies/product-market-codes/H11009 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 615 0$aPharmacology. 615 0$aAllergy. 615 0$aCytology. 615 14$aPharmacology/Toxicology. 615 24$aAllergology. 615 24$aCell Biology. 676 $a615 702 $aPokorski$b Mieczyslaw$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253898603321 996 $aAllergy and Respiration$92503137 997 $aUNINA