LEADER 08429nam 2200709Ia 450 001 9910962019103321 005 20251017110058.0 010 $a9786610192021 010 $a9781280192029 010 $a128019202X 010 $a9780309589659 010 $a0309589657 010 $a9780585154640 010 $a0585154643 035 $a(CKB)110986584751876 035 $a(SSID)ssj0000236789 035 $a(PQKBManifestationID)11202926 035 $a(PQKBTitleCode)TC0000236789 035 $a(PQKBWorkID)10189003 035 $a(PQKB)11753753 035 $a(MiAaPQ)EBC3376246 035 $a(Au-PeEL)EBL3376246 035 $a(CaPaEBR)ebr10055279 035 $a(CaONFJC)MIL19202 035 $a(OCoLC)923262262 035 $a(Perlego)4740601 035 $a(DNLM)821482 035 $a(BIP)47302688 035 $a(EXLCZ)99110986584751876 100 $a19961106d1996 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aResource sharing in biomedical research /$fCommittee on Resource Sharing in Biomedical Research, Division of Health Sciences Policy, Institute of Medicine ; Kenneth I. Berns, Enriqueta C. Bond, and Frederick J. Manning, editors 205 $a1st ed. 210 $aWashington, D.C. $cNational Academy Press$d1996 215 $aviii, 96 p. $cill 300 $a"Report on a workshop, held in Washington, D.C., January 22-23, 1996"--Pref. 311 08$a9780309055826 311 08$a0309055822 320 $aIncludes bibliographical references. 327 $aIntro -- Copyright -- Preface -- Contents -- Executive Summary -- CASE STUDIES -- The American Type Culture Collection -- The Multinational Coordinated Arabidopsis Thaliana Genome Research Project -- The Jackson Laboratory -- The Washington Regional Primate Research Center -- The Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source -- The Human Genome Center at Lawrence Livermore National Laboratory -- CONCLUSIONS AND RECOMMENDATIONS -- Features of Successful Resource Sharing -- Strong Scientific Leadership in Agencies and the Research Community -- Adequate Core Funding -- Marketing and Advertising -- Clear Guidelines about Ownership and Access -- User Fees -- Clear Policies for Retaining and Discarding Data and Material -- Quality Control -- Well-Defined Policies for Function of Research and Service at the Facility -- Sophisticated Information Retrieval and Transfer Systems -- Issues and Problems -- One Uniform Policy on Resource Sharing is Not Possible -- Incentives and Rewards for Resource Sharing are Not Fully Developed -- Methods for Enforcing Existing Policies on Resource Sharing are Inadequate -- There are Many Private and Public Stakeholders in Any Major Resource Sharing Attempt, Often with Conflicting Goals -- Who Pays and What Do They Pay for? -- Regulatory Requirements and Documentation Can Be Unnecessarily Complex and Burdensome -- Education of Scientists Covers Neither the Ethos of Sharing Nor Intellectual and Tangible Property Issues -- Resource Sharing Can Have National and International Implications -- There is a Gap in Leadership -- Partnerships in Resource Sharing May Be Unequal -- Monopolies Can Be Good or Bad -- RECOMMENDATIONS -- 1 Introduction -- COMPETITION FOR FUNDS -- INCENTIVES FOR SCIENTISTS -- NATIONALISM -- METHODS AND GOALS OF THIS STUDY -- A Member Survey -- The Committee. 327 $aThe Workshop -- The Report and Its Recommendations -- REFERENCES -- 2 The American Type Culture Collection -- GENERAL FACILITIES -- PROGRAMS -- Collection, Research, and Services Program -- Professional Services Program -- Education Services Program -- Information Services Program -- OWNERSHIP AND ACCESS ISSUES -- COST ISSUES -- OTHER ISSUES AND PROBLEMS -- 3 The Multinational Coordinated Arabidopsis Thaliana Genome Research Project -- PROJECT ELEMENTS -- OWNERSHIP AND ACCESS ISSUES -- COST ISSUES -- OTHER ISSUES AND PROBLEMS -- 4 The Jackson Laboratory -- ANIMAL RESOURCE PROGRAMS -- Production, Sale, Derivation, and Maintenance of Mice -- Preservation -- Derivation -- Surgery -- Bioinformatics -- OWNERSHIP AND ACCESS ISSUES -- COST ISSUES -- OTHER ISSUES AND PROBLEMS -- 5 The Washington Regional Primate Research Center -- FACILITIES AND PROGRAMS -- OWNERSHIP AND ACCESS ISSUES -- COST ISSUES -- OTHER ISSUES AND PROBLEMS -- 6 The Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source -- USER FACILITIES FOR PROTEIN CRYSTALLOGRAPHY AT SYNCHROTRONS -- THE MACCHESS RESEARCH RESOURCE -- Core Research Projects -- Collaborative Research Projects -- User Research Projects (Service) -- Training and Dissemination -- Workshops and Symposia -- Training Videos -- CHESS Newsletter -- MacCHESS World Wide Web (WWW) Home Page -- OWNERSHIP AND ACCESS ISSUES -- COST ISSUES -- OTHER ISSUES AND PROBLEMS -- 7 The Human Genome Center: Lawrence Livermore National Laboratory -- LAWRENCE LIVERMORE NATIONAL LABORATORY -- HUMAN GENOME CENTER -- Instrumentation and Technology -- Information -- Biological Materials -- Chromosome 19-Specific Cosmids -- Image Consortium cDNA Clones -- OWNERSHIP AND ACCESS ISSUES -- SUMMARY OF ISSUES AND PROBLEMS -- 8 Conclusions and Recommendations -- FEATURES OF SUCCESSFUL RESOURCE SHARING. 327 $aStrong Scientific Leadership in Agencies and the Research Community -- Adequate Core Funding -- Marketing and Advertising -- Clear Guidelines about Ownership and Access -- User Fees -- Clear Policies for Retaining and Discarding Data and Material -- Quality Control -- Well-Defined Policies for Function of Research and Service at the Facility -- Sophisticated Information Retrieval and Transfer Systems -- ISSUES AND PROBLEMS -- One Uniform Policy on Resource Sharing is Not Possible -- Incentives and Rewards for Resource Sharing are Not Fully Developed -- Sharing Requires Incentives, Not Disincentives -- The Importance of Material and Data Assets Changes Over Time -- Technologies and Needs are Evolving Very Rapidly -- New Definitions of "Publication" May Have to Evolve to Keep Pace with the New Electronic Information Systems -- Methods for Enforcing Existing Policies on Sharing are Inadequate -- There are Many Private and Public Stakeholders in any Major Resource Sharing Attempt, Often With Conflicting Goals -- Who Pays and What Do They Pay for? -- Regulatory Requirements and Documentation Can Be Unnecessarily Complex and Burdensome -- Education of Scientists Covers Neither the Ethos of Sharing Nor Intellectual and Tangible Property Issues -- Resource Sharing Can Have National and International Implications -- There is a Gap in Leadership -- Partnerships in Sharing Resources May Be Unequal -- Monopolies Can Be Good or Bad -- RECOMMENDATIONS -- Appendix A Workshop on Resource Sharing in Biomedical Research -- Appendix B Acronyms. 330 $aThe United States is entering an era when, more than ever, the sharing of resources and information might be critical to scientific progress. Every dollar saved by avoiding duplication of efforts and by producing economies of scale will become increasingly important as federal funding enters an era of fiscal restraint. This book focuses on six diverse case studies that share materials or equipment with the scientific community at large: the American Type Culture Collection, the multinational coordinated Arabidopsis thaliana Genome Research Project, the Jackson Laboratory, the Washington Regional Primate Research Center, the Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source, and the Human Genome Center at Lawrence Livermore National Laboratory. The book also identifies common strengths and problems faced in the six cases, and presents a series of recommendations aimed at facilitating resource sharing in biomedical research. 606 $aMedicine$xResearch$zUnited States 606 $aMedical research personnel$zUnited States 615 0$aMedicine$xResearch 615 0$aMedical research personnel 676 $a610/.7/2073 701 $aBerns$b Kenneth I.$f1938-$01806436 701 $aBond$b Enriqueta C$01806437 701 $aManning$b Frederick J$01806438 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910962019103321 996 $aResource sharing in biomedical research$94355617 997 $aUNINA